| Full name: BTB domain containing 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 55643 | HGNC ID: HGNC:15504 | Ensembl Gene: ENSG00000133243 | OMIM ID: 608531 |
| Drug and gene relationship at DGIdb | |||
Expression of BTBD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTBD2 | 55643 | 207722_s_at | 0.3405 | 0.2889 | |
| GSE20347 | BTBD2 | 55643 | 207722_s_at | 0.1739 | 0.3038 | |
| GSE23400 | BTBD2 | 55643 | 207722_s_at | 0.2032 | 0.0072 | |
| GSE26886 | BTBD2 | 55643 | 207722_s_at | 0.0423 | 0.8642 | |
| GSE29001 | BTBD2 | 55643 | 207722_s_at | 0.1369 | 0.5044 | |
| GSE38129 | BTBD2 | 55643 | 207722_s_at | 0.2127 | 0.0945 | |
| GSE45670 | BTBD2 | 55643 | 207722_s_at | 0.0971 | 0.2701 | |
| GSE53622 | BTBD2 | 55643 | 42791 | 0.3430 | 0.0000 | |
| GSE53624 | BTBD2 | 55643 | 42791 | 0.5926 | 0.0000 | |
| GSE63941 | BTBD2 | 55643 | 207722_s_at | 1.5508 | 0.0005 | |
| GSE77861 | BTBD2 | 55643 | 207722_s_at | 0.2781 | 0.1411 | |
| GSE97050 | BTBD2 | 55643 | A_33_P3303066 | 0.2524 | 0.3796 | |
| SRP007169 | BTBD2 | 55643 | RNAseq | -0.1927 | 0.5844 | |
| SRP008496 | BTBD2 | 55643 | RNAseq | -0.3565 | 0.1317 | |
| SRP064894 | BTBD2 | 55643 | RNAseq | 0.3676 | 0.1117 | |
| SRP133303 | BTBD2 | 55643 | RNAseq | 0.0876 | 0.6338 | |
| SRP159526 | BTBD2 | 55643 | RNAseq | 0.6433 | 0.0931 | |
| SRP193095 | BTBD2 | 55643 | RNAseq | 0.1246 | 0.2765 | |
| SRP219564 | BTBD2 | 55643 | RNAseq | 0.2134 | 0.5659 | |
| TCGA | BTBD2 | 55643 | RNAseq | 0.1049 | 0.0189 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by BTBD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTBD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTBD2 | 55643 | 4 | 6 | 20 | |
| GSE20123 | BTBD2 | 55643 | 4 | 5 | 21 | |
| GSE43470 | BTBD2 | 55643 | 1 | 10 | 32 | |
| GSE46452 | BTBD2 | 55643 | 47 | 1 | 11 | |
| GSE47630 | BTBD2 | 55643 | 5 | 7 | 28 | |
| GSE54993 | BTBD2 | 55643 | 16 | 3 | 51 | |
| GSE54994 | BTBD2 | 55643 | 8 | 15 | 30 | |
| GSE60625 | BTBD2 | 55643 | 9 | 0 | 2 | |
| GSE74703 | BTBD2 | 55643 | 1 | 7 | 28 | |
| GSE74704 | BTBD2 | 55643 | 3 | 3 | 14 | |
| TCGA | BTBD2 | 55643 | 6 | 24 | 66 |
Total number of gains: 104; Total number of losses: 81; Total Number of normals: 303.
Somatic mutations of BTBD2:
Generating mutation plots.
Highly correlated genes for BTBD2:
Showing top 20/918 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTBD2 | EPS15L1 | 0.785249 | 3 | 0 | 3 |
| BTBD2 | DNAJC19 | 0.751713 | 3 | 0 | 3 |
| BTBD2 | CTF1 | 0.75083 | 3 | 0 | 3 |
| BTBD2 | PPP2R1A | 0.73711 | 3 | 0 | 3 |
| BTBD2 | ZBED1 | 0.731954 | 3 | 0 | 3 |
| BTBD2 | ADO | 0.731641 | 3 | 0 | 3 |
| BTBD2 | ZNF414 | 0.725227 | 3 | 0 | 3 |
| BTBD2 | SH2B2 | 0.721019 | 3 | 0 | 3 |
| BTBD2 | HEATR6 | 0.72064 | 3 | 0 | 3 |
| BTBD2 | LILRA4 | 0.719275 | 3 | 0 | 3 |
| BTBD2 | IRF2BPL | 0.718329 | 3 | 0 | 3 |
| BTBD2 | MED24 | 0.716294 | 3 | 0 | 3 |
| BTBD2 | CRYBA1 | 0.71531 | 3 | 0 | 3 |
| BTBD2 | RAVER1 | 0.715165 | 5 | 0 | 5 |
| BTBD2 | FAM86C1 | 0.712583 | 5 | 0 | 4 |
| BTBD2 | DENND3 | 0.711677 | 3 | 0 | 3 |
| BTBD2 | TBC1D25 | 0.71142 | 3 | 0 | 3 |
| BTBD2 | FAM89B | 0.710581 | 6 | 0 | 6 |
| BTBD2 | CRTC2 | 0.701995 | 4 | 0 | 4 |
| BTBD2 | NACC1 | 0.701158 | 4 | 0 | 4 |
For details and further investigation, click here
