| Full name: centrosomal protein 85 | Alias Symbol: DKFZP434L0117 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 64793 | HGNC ID: HGNC:25309 | Ensembl Gene: ENSG00000130695 | OMIM ID: |
Screen Evidence:
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Expression of CEP85:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEP85 | 64793 | 227818_at | 0.7104 | 0.0148 | |
| GSE20347 | CEP85 | 64793 | 219611_s_at | 0.3622 | 0.0000 | |
| GSE23400 | CEP85 | 64793 | 219611_s_at | 0.2532 | 0.0000 | |
| GSE26886 | CEP85 | 64793 | 227818_at | -0.3860 | 0.0900 | |
| GSE29001 | CEP85 | 64793 | 219611_s_at | 0.0940 | 0.6357 | |
| GSE38129 | CEP85 | 64793 | 219611_s_at | 0.4042 | 0.0000 | |
| GSE45670 | CEP85 | 64793 | 227818_at | 0.6912 | 0.0001 | |
| GSE53622 | CEP85 | 64793 | 37978 | 1.0632 | 0.0000 | |
| GSE53624 | CEP85 | 64793 | 37978 | 1.1354 | 0.0000 | |
| GSE63941 | CEP85 | 64793 | 219611_s_at | 1.5579 | 0.0002 | |
| GSE77861 | CEP85 | 64793 | 219611_s_at | 0.1022 | 0.4834 | |
| GSE97050 | CEP85 | 64793 | A_23_P200874 | 0.6104 | 0.1399 | |
| SRP007169 | CEP85 | 64793 | RNAseq | 1.5272 | 0.0007 | |
| SRP008496 | CEP85 | 64793 | RNAseq | 0.9936 | 0.0017 | |
| SRP064894 | CEP85 | 64793 | RNAseq | 0.7681 | 0.0049 | |
| SRP133303 | CEP85 | 64793 | RNAseq | 0.8595 | 0.0000 | |
| SRP159526 | CEP85 | 64793 | RNAseq | 1.0066 | 0.0005 | |
| SRP193095 | CEP85 | 64793 | RNAseq | 0.4985 | 0.0001 | |
| SRP219564 | CEP85 | 64793 | RNAseq | 0.5701 | 0.2242 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by CEP85 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CEP85:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEP85 | 64793 | 0 | 6 | 24 | |
| GSE20123 | CEP85 | 64793 | 0 | 5 | 25 | |
| GSE43470 | CEP85 | 64793 | 2 | 6 | 35 | |
| GSE46452 | CEP85 | 64793 | 5 | 1 | 53 | |
| GSE47630 | CEP85 | 64793 | 8 | 3 | 29 | |
| GSE54993 | CEP85 | 64793 | 2 | 1 | 67 | |
| GSE54994 | CEP85 | 64793 | 10 | 4 | 39 | |
| GSE60625 | CEP85 | 64793 | 0 | 0 | 11 | |
| GSE74703 | CEP85 | 64793 | 1 | 4 | 31 | |
| GSE74704 | CEP85 | 64793 | 0 | 0 | 20 | |
| TCGA | CEP85 | 64793 | 9 | 24 | 63 |
Total number of gains: 37; Total number of losses: 54; Total Number of normals: 397.
Somatic mutations of CEP85:
Generating mutation plots.
Highly correlated genes for CEP85:
Showing top 20/966 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEP85 | MARS2 | 0.82936 | 3 | 0 | 3 |
| CEP85 | ESCO2 | 0.79795 | 5 | 0 | 5 |
| CEP85 | IQGAP3 | 0.786832 | 5 | 0 | 5 |
| CEP85 | DKC1 | 0.782971 | 3 | 0 | 3 |
| CEP85 | EBNA1BP2 | 0.753331 | 3 | 0 | 3 |
| CEP85 | UBE2T | 0.751227 | 7 | 0 | 7 |
| CEP85 | ANAPC1 | 0.750186 | 3 | 0 | 3 |
| CEP85 | DEPDC1 | 0.748372 | 8 | 0 | 8 |
| CEP85 | NUF2 | 0.737177 | 7 | 0 | 7 |
| CEP85 | MTHFD1L | 0.733118 | 3 | 0 | 3 |
| CEP85 | SCNM1 | 0.731062 | 3 | 0 | 3 |
| CEP85 | PPP1R9B | 0.727484 | 3 | 0 | 3 |
| CEP85 | ZNF707 | 0.724242 | 3 | 0 | 3 |
| CEP85 | CISD2 | 0.722864 | 3 | 0 | 3 |
| CEP85 | EPS15L1 | 0.722312 | 3 | 0 | 3 |
| CEP85 | TMEM189 | 0.722236 | 3 | 0 | 3 |
| CEP85 | MTBP | 0.721494 | 6 | 0 | 6 |
| CEP85 | HJURP | 0.71796 | 10 | 0 | 10 |
| CEP85 | MRPL41 | 0.717485 | 3 | 0 | 3 |
| CEP85 | PMS2 | 0.71687 | 3 | 0 | 3 |
For details and further investigation, click here
