| Full name: homeodomain interacting protein kinase 1 | Alias Symbol: KIAA0630|Myak|MGC26642|Nbak2|MGC33446|MGC33548 | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 204851 | HGNC ID: HGNC:19006 | Ensembl Gene: ENSG00000163349 | OMIM ID: 608003 |
| Drug and gene relationship at DGIdb | |||
Expression of HIPK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HIPK1 | 204851 | 212293_at | -0.5239 | 0.3431 | |
| GSE20347 | HIPK1 | 204851 | 212293_at | -0.8868 | 0.0000 | |
| GSE23400 | HIPK1 | 204851 | 212293_at | -0.5285 | 0.0000 | |
| GSE26886 | HIPK1 | 204851 | 212293_at | -1.3968 | 0.0000 | |
| GSE29001 | HIPK1 | 204851 | 212293_at | -0.5895 | 0.0100 | |
| GSE38129 | HIPK1 | 204851 | 212293_at | -0.7361 | 0.0000 | |
| GSE45670 | HIPK1 | 204851 | 212293_at | -0.6463 | 0.0001 | |
| GSE53622 | HIPK1 | 204851 | 33572 | -0.6004 | 0.0000 | |
| GSE53624 | HIPK1 | 204851 | 2177 | -0.8090 | 0.0000 | |
| GSE63941 | HIPK1 | 204851 | 212293_at | -0.5227 | 0.3456 | |
| GSE77861 | HIPK1 | 204851 | 212293_at | -0.8925 | 0.0016 | |
| GSE97050 | HIPK1 | 204851 | A_24_P385336 | -0.2674 | 0.2079 | |
| SRP007169 | HIPK1 | 204851 | RNAseq | -1.2666 | 0.0002 | |
| SRP008496 | HIPK1 | 204851 | RNAseq | -1.4344 | 0.0000 | |
| SRP064894 | HIPK1 | 204851 | RNAseq | -0.7774 | 0.0050 | |
| SRP133303 | HIPK1 | 204851 | RNAseq | -0.4501 | 0.0001 | |
| SRP159526 | HIPK1 | 204851 | RNAseq | -1.1155 | 0.0000 | |
| SRP193095 | HIPK1 | 204851 | RNAseq | -0.6778 | 0.0000 | |
| SRP219564 | HIPK1 | 204851 | RNAseq | -0.6053 | 0.2317 | |
| TCGA | HIPK1 | 204851 | RNAseq | -0.1887 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by HIPK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HIPK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HIPK1 | 204851 | 0 | 9 | 21 | |
| GSE20123 | HIPK1 | 204851 | 0 | 9 | 21 | |
| GSE43470 | HIPK1 | 204851 | 0 | 8 | 35 | |
| GSE46452 | HIPK1 | 204851 | 2 | 1 | 56 | |
| GSE47630 | HIPK1 | 204851 | 9 | 5 | 26 | |
| GSE54993 | HIPK1 | 204851 | 0 | 1 | 69 | |
| GSE54994 | HIPK1 | 204851 | 7 | 3 | 43 | |
| GSE60625 | HIPK1 | 204851 | 0 | 0 | 11 | |
| GSE74703 | HIPK1 | 204851 | 0 | 7 | 29 | |
| GSE74704 | HIPK1 | 204851 | 0 | 5 | 15 | |
| TCGA | HIPK1 | 204851 | 11 | 30 | 55 |
Total number of gains: 29; Total number of losses: 78; Total Number of normals: 381.
Somatic mutations of HIPK1:
Generating mutation plots.
Highly correlated genes for HIPK1:
Showing top 20/1639 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HIPK1 | C16orf72 | 0.813124 | 3 | 0 | 3 |
| HIPK1 | SEC23IP | 0.798052 | 3 | 0 | 3 |
| HIPK1 | MPP7 | 0.772156 | 7 | 0 | 7 |
| HIPK1 | FIS1 | 0.769442 | 3 | 0 | 3 |
| HIPK1 | ZNF416 | 0.769262 | 5 | 0 | 5 |
| HIPK1 | SOCS5 | 0.758428 | 3 | 0 | 3 |
| HIPK1 | ESYT2 | 0.757074 | 5 | 0 | 5 |
| HIPK1 | PDIK1L | 0.756009 | 4 | 0 | 3 |
| HIPK1 | C2CD2 | 0.755117 | 3 | 0 | 3 |
| HIPK1 | EAF1 | 0.754927 | 3 | 0 | 3 |
| HIPK1 | NFIA | 0.7471 | 5 | 0 | 5 |
| HIPK1 | CSDE1 | 0.746769 | 10 | 0 | 9 |
| HIPK1 | MRPL46 | 0.746392 | 3 | 0 | 3 |
| HIPK1 | UQCRC2 | 0.74604 | 4 | 0 | 4 |
| HIPK1 | LRRFIP2 | 0.74095 | 9 | 0 | 9 |
| HIPK1 | SH3GLB1 | 0.740666 | 9 | 0 | 8 |
| HIPK1 | SORT1 | 0.739569 | 12 | 0 | 11 |
| HIPK1 | DCAF10 | 0.736374 | 5 | 0 | 5 |
| HIPK1 | MTMR10 | 0.735349 | 7 | 0 | 6 |
| HIPK1 | ATXN10 | 0.733922 | 3 | 0 | 3 |
For details and further investigation, click here
