| Full name: RAB35, member RAS oncogene family | Alias Symbol: H-ray | ||
| Type: protein-coding gene | Cytoband: 12q24.23 | ||
| Entrez ID: 11021 | HGNC ID: HGNC:9774 | Ensembl Gene: ENSG00000111737 | OMIM ID: 604199 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RAB35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB35 | 11021 | 225620_at | 0.0148 | 0.9779 | |
| GSE20347 | RAB35 | 11021 | 221819_at | -0.3067 | 0.0000 | |
| GSE23400 | RAB35 | 11021 | 221819_at | -0.1625 | 0.0001 | |
| GSE26886 | RAB35 | 11021 | 221819_at | -0.0038 | 0.9812 | |
| GSE29001 | RAB35 | 11021 | 221819_at | -0.2633 | 0.3300 | |
| GSE38129 | RAB35 | 11021 | 221819_at | -0.2295 | 0.0155 | |
| GSE45670 | RAB35 | 11021 | 221819_at | -0.1937 | 0.0223 | |
| GSE53622 | RAB35 | 11021 | 21965 | -0.1910 | 0.0000 | |
| GSE53624 | RAB35 | 11021 | 21965 | -0.1606 | 0.0040 | |
| GSE63941 | RAB35 | 11021 | 221819_at | 0.2632 | 0.1585 | |
| GSE77861 | RAB35 | 11021 | 221819_at | -0.0121 | 0.9399 | |
| GSE97050 | RAB35 | 11021 | A_23_P204484 | -0.0241 | 0.9445 | |
| SRP007169 | RAB35 | 11021 | RNAseq | -1.1933 | 0.0008 | |
| SRP008496 | RAB35 | 11021 | RNAseq | -1.1081 | 0.0000 | |
| SRP064894 | RAB35 | 11021 | RNAseq | -0.3121 | 0.0035 | |
| SRP133303 | RAB35 | 11021 | RNAseq | -0.0611 | 0.6676 | |
| SRP159526 | RAB35 | 11021 | RNAseq | -0.4682 | 0.0464 | |
| SRP193095 | RAB35 | 11021 | RNAseq | -0.2799 | 0.0111 | |
| SRP219564 | RAB35 | 11021 | RNAseq | -0.5456 | 0.0042 | |
| TCGA | RAB35 | 11021 | RNAseq | 0.0488 | 0.3022 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RAB35 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB35 | 11021 | 6 | 2 | 22 | |
| GSE20123 | RAB35 | 11021 | 6 | 2 | 22 | |
| GSE43470 | RAB35 | 11021 | 2 | 2 | 39 | |
| GSE46452 | RAB35 | 11021 | 9 | 1 | 49 | |
| GSE47630 | RAB35 | 11021 | 9 | 3 | 28 | |
| GSE54993 | RAB35 | 11021 | 0 | 5 | 65 | |
| GSE54994 | RAB35 | 11021 | 7 | 6 | 40 | |
| GSE60625 | RAB35 | 11021 | 0 | 0 | 11 | |
| GSE74703 | RAB35 | 11021 | 2 | 1 | 33 | |
| GSE74704 | RAB35 | 11021 | 3 | 2 | 15 | |
| TCGA | RAB35 | 11021 | 20 | 11 | 65 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of RAB35:
Generating mutation plots.
Highly correlated genes for RAB35:
Showing top 20/386 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB35 | EPS15L1 | 0.818051 | 4 | 0 | 4 |
| RAB35 | TRAFD1 | 0.788215 | 3 | 0 | 3 |
| RAB35 | CCIN | 0.758487 | 3 | 0 | 3 |
| RAB35 | FAM89B | 0.756285 | 3 | 0 | 3 |
| RAB35 | GLUD1 | 0.75421 | 3 | 0 | 3 |
| RAB35 | CSNK1D | 0.740246 | 3 | 0 | 3 |
| RAB35 | VCP | 0.739679 | 3 | 0 | 3 |
| RAB35 | VWA5A | 0.721271 | 3 | 0 | 3 |
| RAB35 | GEMIN7 | 0.721125 | 3 | 0 | 3 |
| RAB35 | EMCN | 0.719534 | 3 | 0 | 3 |
| RAB35 | FAM149B1 | 0.713027 | 3 | 0 | 3 |
| RAB35 | ROR1 | 0.710416 | 3 | 0 | 3 |
| RAB35 | CD6 | 0.710321 | 3 | 0 | 3 |
| RAB35 | ADAD2 | 0.706624 | 3 | 0 | 3 |
| RAB35 | RRAGC | 0.70616 | 3 | 0 | 3 |
| RAB35 | DEXI | 0.70563 | 3 | 0 | 3 |
| RAB35 | TBC1D22A | 0.704655 | 4 | 0 | 3 |
| RAB35 | MED26 | 0.702124 | 3 | 0 | 3 |
| RAB35 | ARF3 | 0.700117 | 3 | 0 | 3 |
| RAB35 | PACSIN3 | 0.699869 | 4 | 0 | 3 |
For details and further investigation, click here
