| Full name: ETS2 repressor factor | Alias Symbol: PE-2|PE2 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 2077 | HGNC ID: HGNC:3444 | Ensembl Gene: ENSG00000105722 | OMIM ID: 611888 |
| Drug and gene relationship at DGIdb | |||
Expression of ERF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERF | 2077 | 203643_at | 0.8305 | 0.0726 | |
| GSE20347 | ERF | 2077 | 203643_at | 0.8298 | 0.0000 | |
| GSE23400 | ERF | 2077 | 203643_at | 0.3881 | 0.0000 | |
| GSE26886 | ERF | 2077 | 230368_at | 0.2192 | 0.2288 | |
| GSE29001 | ERF | 2077 | 203643_at | 0.3115 | 0.3116 | |
| GSE38129 | ERF | 2077 | 203643_at | 0.7234 | 0.0002 | |
| GSE45670 | ERF | 2077 | 203643_at | 0.3807 | 0.0594 | |
| GSE53622 | ERF | 2077 | 66918 | 0.7503 | 0.0000 | |
| GSE53624 | ERF | 2077 | 66918 | 1.1185 | 0.0000 | |
| GSE63941 | ERF | 2077 | 203643_at | 0.8523 | 0.0461 | |
| GSE77861 | ERF | 2077 | 203643_at | 0.6851 | 0.0044 | |
| GSE97050 | ERF | 2077 | A_23_P4679 | -0.2920 | 0.4541 | |
| SRP007169 | ERF | 2077 | RNAseq | 2.1027 | 0.0000 | |
| SRP008496 | ERF | 2077 | RNAseq | 1.8453 | 0.0000 | |
| SRP064894 | ERF | 2077 | RNAseq | 0.4412 | 0.0555 | |
| SRP133303 | ERF | 2077 | RNAseq | 0.7597 | 0.0049 | |
| SRP159526 | ERF | 2077 | RNAseq | 1.3808 | 0.0032 | |
| SRP193095 | ERF | 2077 | RNAseq | 1.1498 | 0.0000 | |
| SRP219564 | ERF | 2077 | RNAseq | -0.1643 | 0.6959 | |
| TCGA | ERF | 2077 | RNAseq | 0.1599 | 0.0100 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by ERF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERF | 2077 | 4 | 4 | 22 | |
| GSE20123 | ERF | 2077 | 4 | 3 | 23 | |
| GSE43470 | ERF | 2077 | 4 | 11 | 28 | |
| GSE46452 | ERF | 2077 | 47 | 1 | 11 | |
| GSE47630 | ERF | 2077 | 8 | 6 | 26 | |
| GSE54993 | ERF | 2077 | 17 | 4 | 49 | |
| GSE54994 | ERF | 2077 | 7 | 12 | 34 | |
| GSE60625 | ERF | 2077 | 9 | 0 | 2 | |
| GSE74703 | ERF | 2077 | 4 | 7 | 25 | |
| GSE74704 | ERF | 2077 | 4 | 1 | 15 | |
| TCGA | ERF | 2077 | 13 | 16 | 67 |
Total number of gains: 121; Total number of losses: 65; Total Number of normals: 302.
Somatic mutations of ERF:
Generating mutation plots.
Highly correlated genes for ERF:
Showing top 20/1438 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERF | BCL9 | 0.82013 | 3 | 0 | 3 |
| ERF | RILPL1 | 0.760852 | 4 | 0 | 4 |
| ERF | RAB34 | 0.742106 | 3 | 0 | 3 |
| ERF | FADS1 | 0.738053 | 3 | 0 | 3 |
| ERF | PRSS36 | 0.724507 | 3 | 0 | 3 |
| ERF | MEX3B | 0.712218 | 3 | 0 | 3 |
| ERF | TEAD2 | 0.712138 | 5 | 0 | 5 |
| ERF | TUBA1B | 0.706744 | 7 | 0 | 7 |
| ERF | SERPINH1 | 0.705062 | 8 | 0 | 8 |
| ERF | PCYT1B | 0.692644 | 3 | 0 | 3 |
| ERF | NFATC4 | 0.686191 | 3 | 0 | 3 |
| ERF | YWHAG | 0.683199 | 5 | 0 | 4 |
| ERF | BCL9L | 0.681179 | 4 | 0 | 3 |
| ERF | SLC25A32 | 0.679268 | 9 | 0 | 9 |
| ERF | SOGA1 | 0.67878 | 4 | 0 | 3 |
| ERF | TTBK2 | 0.677218 | 4 | 0 | 4 |
| ERF | SLC41A1 | 0.676653 | 6 | 0 | 6 |
| ERF | CEP170 | 0.676371 | 3 | 0 | 3 |
| ERF | GOLM1 | 0.676201 | 3 | 0 | 3 |
| ERF | ZNF114 | 0.675042 | 4 | 0 | 4 |
For details and further investigation, click here
