| Full name: zinc finger protein 114 | Alias Symbol: MGC17986 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 163071 | HGNC ID: HGNC:12894 | Ensembl Gene: ENSG00000178150 | OMIM ID: 603996 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF114:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF114 | 163071 | 1552946_at | 1.3131 | 0.1244 | |
| GSE26886 | ZNF114 | 163071 | 1552946_at | 1.6883 | 0.0001 | |
| GSE45670 | ZNF114 | 163071 | 1552947_x_at | 1.3152 | 0.0038 | |
| GSE63941 | ZNF114 | 163071 | 1552946_at | 2.2458 | 0.0835 | |
| GSE77861 | ZNF114 | 163071 | 1552947_x_at | 0.3439 | 0.0605 | |
| SRP007169 | ZNF114 | 163071 | RNAseq | 1.6840 | 0.0037 | |
| SRP064894 | ZNF114 | 163071 | RNAseq | 2.3611 | 0.0000 | |
| SRP133303 | ZNF114 | 163071 | RNAseq | 1.2442 | 0.0000 | |
| SRP159526 | ZNF114 | 163071 | RNAseq | 1.6607 | 0.0000 | |
| SRP193095 | ZNF114 | 163071 | RNAseq | 1.1670 | 0.0000 | |
| SRP219564 | ZNF114 | 163071 | RNAseq | 2.0852 | 0.0005 | |
| TCGA | ZNF114 | 163071 | RNAseq | 2.9748 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by ZNF114 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZNF114:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF114 | 163071 | 4 | 4 | 22 | |
| GSE20123 | ZNF114 | 163071 | 4 | 3 | 23 | |
| GSE43470 | ZNF114 | 163071 | 3 | 11 | 29 | |
| GSE46452 | ZNF114 | 163071 | 45 | 1 | 13 | |
| GSE47630 | ZNF114 | 163071 | 9 | 6 | 25 | |
| GSE54993 | ZNF114 | 163071 | 17 | 4 | 49 | |
| GSE54994 | ZNF114 | 163071 | 4 | 14 | 35 | |
| GSE60625 | ZNF114 | 163071 | 9 | 0 | 2 | |
| GSE74703 | ZNF114 | 163071 | 3 | 7 | 26 | |
| GSE74704 | ZNF114 | 163071 | 4 | 1 | 15 | |
| TCGA | ZNF114 | 163071 | 15 | 19 | 62 |
Total number of gains: 117; Total number of losses: 70; Total Number of normals: 301.
Somatic mutations of ZNF114:
Generating mutation plots.
Highly correlated genes for ZNF114:
Showing top 20/766 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF114 | PPP4R4 | 0.777898 | 4 | 0 | 4 |
| ZNF114 | CERCAM | 0.762837 | 3 | 0 | 3 |
| ZNF114 | FBLIM1 | 0.760637 | 4 | 0 | 4 |
| ZNF114 | TNFRSF12A | 0.759446 | 4 | 0 | 4 |
| ZNF114 | WDHD1 | 0.759366 | 5 | 0 | 5 |
| ZNF114 | STC2 | 0.756368 | 4 | 0 | 4 |
| ZNF114 | DNMT3B | 0.754734 | 5 | 0 | 4 |
| ZNF114 | CYP27C1 | 0.748856 | 4 | 0 | 4 |
| ZNF114 | FADS2 | 0.747202 | 3 | 0 | 3 |
| ZNF114 | TMEM185B | 0.746342 | 3 | 0 | 3 |
| ZNF114 | VRK1 | 0.743371 | 5 | 0 | 5 |
| ZNF114 | PTHLH | 0.740375 | 4 | 0 | 4 |
| ZNF114 | LPAR3 | 0.73748 | 3 | 0 | 3 |
| ZNF114 | SLC39A1 | 0.736996 | 3 | 0 | 3 |
| ZNF114 | TAGLN2 | 0.734092 | 3 | 0 | 3 |
| ZNF114 | L3HYPDH | 0.731288 | 4 | 0 | 4 |
| ZNF114 | SLC2A1 | 0.725116 | 4 | 0 | 3 |
| ZNF114 | PDPN | 0.724505 | 3 | 0 | 3 |
| ZNF114 | RNMT | 0.723079 | 3 | 0 | 3 |
| ZNF114 | BRMS1 | 0.721201 | 3 | 0 | 3 |
For details and further investigation, click here
