| Full name: mex-3 RNA binding family member B | Alias Symbol: DKFZp434J0617|RNF195 | ||
| Type: protein-coding gene | Cytoband: 15q25.2 | ||
| Entrez ID: 84206 | HGNC ID: HGNC:25297 | Ensembl Gene: ENSG00000183496 | OMIM ID: 611008 |
| Drug and gene relationship at DGIdb | |||
Expression of MEX3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEX3B | 84206 | 223627_at | 0.3883 | 0.2429 | |
| GSE26886 | MEX3B | 84206 | 223627_at | 0.1269 | 0.1737 | |
| GSE45670 | MEX3B | 84206 | 223627_at | 0.1591 | 0.5464 | |
| GSE53622 | MEX3B | 84206 | 30678 | 1.7163 | 0.0000 | |
| GSE53624 | MEX3B | 84206 | 30678 | 1.7334 | 0.0000 | |
| GSE63941 | MEX3B | 84206 | 223627_at | -1.3581 | 0.0290 | |
| GSE77861 | MEX3B | 84206 | 223627_at | -0.0392 | 0.7159 | |
| GSE97050 | MEX3B | 84206 | A_24_P65060 | 0.2441 | 0.3581 | |
| SRP007169 | MEX3B | 84206 | RNAseq | 1.7743 | 0.0208 | |
| SRP008496 | MEX3B | 84206 | RNAseq | 2.2537 | 0.0000 | |
| SRP133303 | MEX3B | 84206 | RNAseq | 1.8062 | 0.0000 | |
| SRP159526 | MEX3B | 84206 | RNAseq | 1.4090 | 0.0099 | |
| SRP219564 | MEX3B | 84206 | RNAseq | 0.6158 | 0.0580 | |
| TCGA | MEX3B | 84206 | RNAseq | 0.6764 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 1.
Survival by MEX3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEX3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEX3B | 84206 | 7 | 1 | 22 | |
| GSE20123 | MEX3B | 84206 | 7 | 1 | 22 | |
| GSE43470 | MEX3B | 84206 | 4 | 4 | 35 | |
| GSE46452 | MEX3B | 84206 | 3 | 7 | 49 | |
| GSE47630 | MEX3B | 84206 | 8 | 10 | 22 | |
| GSE54993 | MEX3B | 84206 | 5 | 6 | 59 | |
| GSE54994 | MEX3B | 84206 | 5 | 7 | 41 | |
| GSE60625 | MEX3B | 84206 | 4 | 0 | 7 | |
| GSE74703 | MEX3B | 84206 | 4 | 2 | 30 | |
| GSE74704 | MEX3B | 84206 | 3 | 1 | 16 | |
| TCGA | MEX3B | 84206 | 15 | 14 | 67 |
Total number of gains: 65; Total number of losses: 53; Total Number of normals: 370.
Somatic mutations of MEX3B:
Generating mutation plots.
Highly correlated genes for MEX3B:
Showing top 20/795 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEX3B | DHX38 | 0.808042 | 3 | 0 | 3 |
| MEX3B | CENPL | 0.77605 | 3 | 0 | 3 |
| MEX3B | GNPDA1 | 0.766086 | 4 | 0 | 4 |
| MEX3B | RAB34 | 0.76555 | 3 | 0 | 3 |
| MEX3B | CNIH3 | 0.763851 | 4 | 0 | 4 |
| MEX3B | PRSS36 | 0.753268 | 3 | 0 | 3 |
| MEX3B | BCL2A1 | 0.751864 | 4 | 0 | 4 |
| MEX3B | CEP170 | 0.748726 | 3 | 0 | 3 |
| MEX3B | ENC1 | 0.739975 | 3 | 0 | 3 |
| MEX3B | FCGR3A | 0.734698 | 3 | 0 | 3 |
| MEX3B | LAPTM4B | 0.734292 | 4 | 0 | 4 |
| MEX3B | FADS1 | 0.72955 | 3 | 0 | 3 |
| MEX3B | EXTL3 | 0.72833 | 4 | 0 | 4 |
| MEX3B | PAIP1 | 0.725391 | 3 | 0 | 3 |
| MEX3B | RHEB | 0.724925 | 3 | 0 | 3 |
| MEX3B | LRRC8C | 0.724055 | 3 | 0 | 3 |
| MEX3B | ZBTB2 | 0.722705 | 3 | 0 | 3 |
| MEX3B | SLBP | 0.720134 | 3 | 0 | 3 |
| MEX3B | ZC3H7B | 0.7199 | 3 | 0 | 3 |
| MEX3B | TDO2 | 0.719778 | 4 | 0 | 4 |
For details and further investigation, click here
