SERPINH1

 

Full name: serpin family H member 1 Alias Symbol: HSP47|colligen
Type: protein-coding gene Cytoband: 11q13.5
Entrez ID: 871 HGNC ID: HGNC:1546 Ensembl Gene: ENSG00000149257 OMIM ID: 600943
Drug and gene relationship at DGIdb

 

Expression of SERPINH1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SERPINH1 871 207714_s_at 2.2967 0.0086
GSE20347 SERPINH1 871 207714_s_at 1.9145 0.0000
GSE23400 SERPINH1 871 207714_s_at 1.6301 0.0000
GSE26886 SERPINH1 871 207714_s_at 1.4831 0.0000
GSE29001 SERPINH1 871 207714_s_at 1.7838 0.0003
GSE38129 SERPINH1 871 207714_s_at 1.8566 0.0000
GSE45670 SERPINH1 871 207714_s_at 1.6668 0.0002
GSE53622 SERPINH1 871 120383 2.0756 0.0000
GSE53624 SERPINH1 871 120383 2.1287 0.0000
GSE63941 SERPINH1 871 207714_s_at -0.6298 0.2708
GSE77861 SERPINH1 871 207714_s_at 1.5464 0.0024
GSE97050 SERPINH1 871 A_33_P3269203 0.8556 0.0620
SRP007169 SERPINH1 871 RNAseq 2.8933 0.0000
SRP008496 SERPINH1 871 RNAseq 3.1906 0.0000
SRP064894 SERPINH1 871 RNAseq 2.9517 0.0000
SRP133303 SERPINH1 871 RNAseq 2.5199 0.0000
SRP159526 SERPINH1 871 RNAseq 2.1549 0.0000
SRP193095 SERPINH1 871 RNAseq 2.5399 0.0000
SRP219564 SERPINH1 871 RNAseq 1.5852 0.0814
TCGA SERPINH1 871 RNAseq 0.4589 0.0000

Upregulated datasets: 16; Downregulated datasets: 0.  

 

Survival by SERPINH1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SERPINH1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SERPINH1 871 6 8 16
GSE20123 SERPINH1 871 6 7 17
GSE43470 SERPINH1 871 4 4 35
GSE46452 SERPINH1 871 7 22 30
GSE47630 SERPINH1 871 6 14 20
GSE54993 SERPINH1 871 8 2 60
GSE54994 SERPINH1 871 7 16 30
GSE60625 SERPINH1 871 4 3 4
GSE74703 SERPINH1 871 3 3 30
GSE74704 SERPINH1 871 4 3 13
TCGA SERPINH1 871 21 31 44

Total number of gains: 76; Total number of losses: 113; Total Number of normals: 299.  

 

Somatic mutations of SERPINH1:

 

Generating mutation plots.

 

Highly correlated genes for SERPINH1:

 

Showing top 20/1792 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SERPINH1LPCAT10.83879910010
SERPINH1FMNL20.821606606
SERPINH1ENAH0.80868310010
SERPINH1COLGALT10.8084610010
SERPINH1ARPC1B0.80720610010
SERPINH1INHBA0.7948212011
SERPINH1TP53I130.790608505
SERPINH1HOMER30.7897911011
SERPINH1PFDN20.7875110010
SERPINH1LAPTM4B0.78416110010
SERPINH1PLOD30.77850811010
SERPINH1YWHAG0.776978404
SERPINH1CDC25B0.77464310010
SERPINH1TMEM184B0.77290610010
SERPINH1TGFBI0.77261612012
SERPINH1SPP10.76921211011
SERPINH1HOXC90.768438404
SERPINH1ERH0.768223909
SERPINH1MFAP20.76756113011
SERPINH1HSP90AB10.76706210010

For details and further investigation, click here