Full name: esterase D	Alias Symbol:
Type: protein-coding gene	Cytoband: 13q14.2
Entrez ID: 2098	HGNC ID: HGNC:3465	Ensembl Gene: ENSG00000139684	OMIM ID: 133280
Drug and gene relationship at DGIdb
Screen Evidence: Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

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Expression of ESD:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	ESD	2098	209009_at	-0.3706	0.3093	Show
GSE20347	ESD	2098	215096_s_at	-0.2999	0.0275	Show
GSE23400	ESD	2098	209009_at	-0.1100	0.2209	Show
GSE26886	ESD	2098	215096_s_at	0.4768	0.0426	Show
GSE29001	ESD	2098	215096_s_at	-0.2006	0.4166	Show
GSE38129	ESD	2098	215096_s_at	-0.3688	0.0013	Show
GSE45670	ESD	2098	215096_s_at	-0.4434	0.0024	Show
GSE53622	ESD	2098	49321	-0.1145	0.1743	Show
GSE53624	ESD	2098	49321	-0.1299	0.1377	Show
GSE63941	ESD	2098	209009_at	-0.3280	0.3939	Show
GSE77861	ESD	2098	209009_at	-0.1615	0.6628	Show
GSE97050	ESD	2098	A_23_P87964	-0.3293	0.3531	Show
SRP007169	ESD	2098	RNAseq	-0.2989	0.4282	Show
SRP008496	ESD	2098	RNAseq	-0.1875	0.4453	Show
SRP064894	ESD	2098	RNAseq	-0.1168	0.4905	Show
SRP133303	ESD	2098	RNAseq	-0.5024	0.0040	Show
SRP159526	ESD	2098	RNAseq	-0.6549	0.0202	Show
SRP193095	ESD	2098	RNAseq	-0.4992	0.0045	Show
SRP219564	ESD	2098	RNAseq	-0.5326	0.1326	Show
TCGA	ESD	2098	RNAseq	-0.0165	0.7307	Show

Upregulated datasets: 0; Downregulated datasets: 0.  Download Data

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Survival by ESD expression:

 

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Copy number change of ESD:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	ESD	2098	0	14	16	Show
GSE20123	ESD	2098	0	13	17	Show
GSE43470	ESD	2098	3	13	27	Show
GSE46452	ESD	2098	0	33	26	Show
GSE47630	ESD	2098	2	27	11	Show
GSE54993	ESD	2098	12	2	56	Show
GSE54994	ESD	2098	1	16	36	Show
GSE60625	ESD	2098	0	3	8	Show
GSE74703	ESD	2098	3	10	23	Show
GSE74704	ESD	2098	0	10	10	Show
TCGA	ESD	2098	8	37	51	Show

Total number of gains: 29; Total number of losses: 178; Total Number of normals: 281.  Download Data

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Somatic mutations of ESD:

 

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Highly correlated genes for ESD:

 

Showing top 20/319 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
ESD	RIMKLB	0.739305	3	0	3
ESD	AUH	0.707162	3	0	3
ESD	EEF2	0.701416	3	0	3
ESD	GOLGA5	0.682978	3	0	3
ESD	EIF3K	0.677741	3	0	3
ESD	DNAJC18	0.677668	3	0	3
ESD	ZNF383	0.675702	3	0	3
ESD	PFKP	0.668951	4	0	3
ESD	COG3	0.666809	3	0	3
ESD	AGGF1	0.664641	4	0	3
ESD	PTPN21	0.656719	5	0	4
ESD	ZSCAN12	0.655213	3	0	3
ESD	KPNA5	0.65294	4	0	3
ESD	H6PD	0.651312	3	0	3
ESD	ST6GALNAC6	0.650181	4	0	3
ESD	EIF3E	0.647312	4	0	3
ESD	NAP1L1	0.646942	3	0	3
ESD	RPS27A	0.646181	3	0	3
ESD	LYRM7	0.641038	4	0	3
ESD	LRRC47	0.640427	4	0	3

For details and further investigation, click here