| Full name: AU RNA binding methylglutaconyl-CoA hydratase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q22.31 | ||
| Entrez ID: 549 | HGNC ID: HGNC:890 | Ensembl Gene: ENSG00000148090 | OMIM ID: 600529 |
| Drug and gene relationship at DGIdb | |||
Expression of AUH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AUH | 549 | 205052_at | -0.5890 | 0.0439 | |
| GSE20347 | AUH | 549 | 205052_at | -0.1462 | 0.3531 | |
| GSE23400 | AUH | 549 | 205052_at | 0.0466 | 0.4721 | |
| GSE26886 | AUH | 549 | 205052_at | -0.3163 | 0.3293 | |
| GSE29001 | AUH | 549 | 205052_at | 0.0413 | 0.9110 | |
| GSE38129 | AUH | 549 | 205052_at | -0.1854 | 0.1734 | |
| GSE45670 | AUH | 549 | 205052_at | -0.3576 | 0.0210 | |
| GSE53622 | AUH | 549 | 8640 | -0.3112 | 0.0003 | |
| GSE53624 | AUH | 549 | 8640 | -0.2349 | 0.0037 | |
| GSE63941 | AUH | 549 | 205052_at | 0.1485 | 0.8130 | |
| GSE77861 | AUH | 549 | 205052_at | 0.1637 | 0.5036 | |
| GSE97050 | AUH | 549 | A_23_P20852 | -0.0332 | 0.9096 | |
| SRP007169 | AUH | 549 | RNAseq | 0.0207 | 0.9656 | |
| SRP064894 | AUH | 549 | RNAseq | -0.0613 | 0.7063 | |
| SRP133303 | AUH | 549 | RNAseq | -0.0980 | 0.4142 | |
| SRP159526 | AUH | 549 | RNAseq | -0.4536 | 0.0412 | |
| SRP193095 | AUH | 549 | RNAseq | -0.0747 | 0.5159 | |
| SRP219564 | AUH | 549 | RNAseq | 0.1007 | 0.8048 | |
| TCGA | AUH | 549 | RNAseq | -0.4293 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AUH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AUH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AUH | 549 | 6 | 9 | 15 | |
| GSE20123 | AUH | 549 | 6 | 9 | 15 | |
| GSE43470 | AUH | 549 | 6 | 3 | 34 | |
| GSE46452 | AUH | 549 | 6 | 14 | 39 | |
| GSE47630 | AUH | 549 | 1 | 18 | 21 | |
| GSE54993 | AUH | 549 | 4 | 2 | 64 | |
| GSE54994 | AUH | 549 | 7 | 11 | 35 | |
| GSE60625 | AUH | 549 | 0 | 0 | 11 | |
| GSE74703 | AUH | 549 | 5 | 3 | 28 | |
| GSE74704 | AUH | 549 | 3 | 7 | 10 | |
| TCGA | AUH | 549 | 22 | 24 | 50 |
Total number of gains: 66; Total number of losses: 100; Total Number of normals: 322.
Somatic mutations of AUH:
Generating mutation plots.
Highly correlated genes for AUH:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AUH | TUBE1 | 0.725953 | 3 | 0 | 3 |
| AUH | PTPN21 | 0.725051 | 3 | 0 | 3 |
| AUH | TMUB2 | 0.713236 | 3 | 0 | 3 |
| AUH | ESD | 0.707162 | 3 | 0 | 3 |
| AUH | HEMK1 | 0.705448 | 3 | 0 | 3 |
| AUH | TSHZ2 | 0.689695 | 3 | 0 | 3 |
| AUH | PINK1 | 0.684083 | 3 | 0 | 3 |
| AUH | ZMAT1 | 0.66501 | 3 | 0 | 3 |
| AUH | PHLPP1 | 0.66468 | 3 | 0 | 3 |
| AUH | PURA | 0.65653 | 4 | 0 | 3 |
| AUH | DCAF6 | 0.655766 | 3 | 0 | 3 |
| AUH | SCUBE2 | 0.655211 | 3 | 0 | 3 |
| AUH | HINT1 | 0.649296 | 3 | 0 | 3 |
| AUH | BRD8 | 0.646214 | 3 | 0 | 3 |
| AUH | SIK2 | 0.64266 | 4 | 0 | 3 |
| AUH | SSBP2 | 0.64116 | 4 | 0 | 3 |
| AUH | UFL1 | 0.640548 | 4 | 0 | 3 |
| AUH | CDKN1C | 0.639729 | 4 | 0 | 3 |
| AUH | FBXL17 | 0.63732 | 4 | 0 | 3 |
| AUH | MRPS27 | 0.635232 | 4 | 0 | 3 |
For details and further investigation, click here
