| Full name: ETS variant transcription factor 5 | Alias Symbol: ERM | ||
| Type: protein-coding gene | Cytoband: 3q27.2 | ||
| Entrez ID: 2119 | HGNC ID: HGNC:3494 | Ensembl Gene: ENSG00000244405 | OMIM ID: 601600 |
| Drug and gene relationship at DGIdb | |||
Expression of ETV5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETV5 | 2119 | 203349_s_at | 0.4932 | 0.5383 | |
| GSE20347 | ETV5 | 2119 | 203349_s_at | 1.2486 | 0.0010 | |
| GSE23400 | ETV5 | 2119 | 203349_s_at | 0.6746 | 0.0000 | |
| GSE26886 | ETV5 | 2119 | 203349_s_at | 1.1835 | 0.0006 | |
| GSE29001 | ETV5 | 2119 | 203349_s_at | 0.9163 | 0.0608 | |
| GSE38129 | ETV5 | 2119 | 203349_s_at | 1.4467 | 0.0000 | |
| GSE45670 | ETV5 | 2119 | 203349_s_at | 0.3765 | 0.4285 | |
| GSE53622 | ETV5 | 2119 | 6836 | 1.4288 | 0.0000 | |
| GSE53624 | ETV5 | 2119 | 6836 | 1.3577 | 0.0000 | |
| GSE63941 | ETV5 | 2119 | 203349_s_at | -0.8750 | 0.4527 | |
| GSE77861 | ETV5 | 2119 | 203349_s_at | 1.6215 | 0.0014 | |
| GSE97050 | ETV5 | 2119 | A_32_P30649 | 0.6933 | 0.0903 | |
| SRP007169 | ETV5 | 2119 | RNAseq | 3.5542 | 0.0000 | |
| SRP008496 | ETV5 | 2119 | RNAseq | 3.4941 | 0.0000 | |
| SRP064894 | ETV5 | 2119 | RNAseq | 1.3383 | 0.0000 | |
| SRP133303 | ETV5 | 2119 | RNAseq | 1.1928 | 0.0000 | |
| SRP193095 | ETV5 | 2119 | RNAseq | 0.9619 | 0.0002 | |
| SRP219564 | ETV5 | 2119 | RNAseq | 1.5770 | 0.0031 | |
| TCGA | ETV5 | 2119 | RNAseq | 0.0829 | 0.5277 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by ETV5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETV5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETV5 | 2119 | 25 | 0 | 5 | |
| GSE20123 | ETV5 | 2119 | 25 | 0 | 5 | |
| GSE43470 | ETV5 | 2119 | 23 | 0 | 20 | |
| GSE46452 | ETV5 | 2119 | 19 | 1 | 39 | |
| GSE47630 | ETV5 | 2119 | 27 | 2 | 11 | |
| GSE54993 | ETV5 | 2119 | 1 | 19 | 50 | |
| GSE54994 | ETV5 | 2119 | 40 | 0 | 13 | |
| GSE60625 | ETV5 | 2119 | 0 | 6 | 5 | |
| GSE74703 | ETV5 | 2119 | 20 | 0 | 16 | |
| GSE74704 | ETV5 | 2119 | 17 | 0 | 3 | |
| TCGA | ETV5 | 2119 | 77 | 0 | 19 |
Total number of gains: 274; Total number of losses: 28; Total Number of normals: 186.
Somatic mutations of ETV5:
Generating mutation plots.
Highly correlated genes for ETV5:
Showing top 20/1407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETV5 | ALKBH6 | 0.756576 | 3 | 0 | 3 |
| ETV5 | HAS3 | 0.751276 | 4 | 0 | 3 |
| ETV5 | UHMK1 | 0.738679 | 3 | 0 | 3 |
| ETV5 | HEY1 | 0.73744 | 12 | 0 | 11 |
| ETV5 | BMP1 | 0.73413 | 3 | 0 | 3 |
| ETV5 | IDS | 0.727871 | 3 | 0 | 3 |
| ETV5 | CXCL3 | 0.722575 | 4 | 0 | 4 |
| ETV5 | ITGAM | 0.717847 | 4 | 0 | 3 |
| ETV5 | DHX33 | 0.713418 | 5 | 0 | 5 |
| ETV5 | HAUS2 | 0.711632 | 3 | 0 | 3 |
| ETV5 | RPGR | 0.708515 | 3 | 0 | 3 |
| ETV5 | NEDD1 | 0.70457 | 4 | 0 | 4 |
| ETV5 | ZNF496 | 0.701804 | 5 | 0 | 5 |
| ETV5 | NFKBID | 0.700536 | 3 | 0 | 3 |
| ETV5 | SLC41A1 | 0.699767 | 5 | 0 | 4 |
| ETV5 | SSBP4 | 0.697637 | 4 | 0 | 4 |
| ETV5 | DHRSX | 0.695606 | 3 | 0 | 3 |
| ETV5 | MCM3AP | 0.694665 | 3 | 0 | 3 |
| ETV5 | WDR81 | 0.691997 | 4 | 0 | 4 |
| ETV5 | IRAK3 | 0.689751 | 3 | 0 | 3 |
For details and further investigation, click here
