| Full name: sorting nexin 20 | Alias Symbol: SLIC-1|SLIC1 | ||
| Type: protein-coding gene | Cytoband: 16q12.1 | ||
| Entrez ID: 124460 | HGNC ID: HGNC:30390 | Ensembl Gene: ENSG00000167208 | OMIM ID: 613281 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX20 | 124460 | 228869_at | 0.6818 | 0.5098 | |
| GSE26886 | SNX20 | 124460 | 228869_at | -1.1581 | 0.0007 | |
| GSE45670 | SNX20 | 124460 | 228869_at | 0.0802 | 0.8008 | |
| GSE53622 | SNX20 | 124460 | 101077 | -0.0153 | 0.9369 | |
| GSE53624 | SNX20 | 124460 | 101077 | -0.1458 | 0.3551 | |
| GSE63941 | SNX20 | 124460 | 1563641_a_at | -0.0566 | 0.7332 | |
| GSE77861 | SNX20 | 124460 | 228869_at | -0.0983 | 0.5033 | |
| GSE97050 | SNX20 | 124460 | A_24_P13831 | 0.5483 | 0.1898 | |
| SRP007169 | SNX20 | 124460 | RNAseq | 1.4268 | 0.1198 | |
| SRP064894 | SNX20 | 124460 | RNAseq | 0.5488 | 0.0224 | |
| SRP133303 | SNX20 | 124460 | RNAseq | -0.1480 | 0.4855 | |
| SRP159526 | SNX20 | 124460 | RNAseq | -0.7942 | 0.2544 | |
| SRP193095 | SNX20 | 124460 | RNAseq | 0.0211 | 0.8920 | |
| SRP219564 | SNX20 | 124460 | RNAseq | 0.1825 | 0.7425 | |
| TCGA | SNX20 | 124460 | RNAseq | 0.3216 | 0.1536 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SNX20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX20 | 124460 | 3 | 1 | 26 | |
| GSE20123 | SNX20 | 124460 | 3 | 1 | 26 | |
| GSE43470 | SNX20 | 124460 | 2 | 7 | 34 | |
| GSE46452 | SNX20 | 124460 | 38 | 1 | 20 | |
| GSE47630 | SNX20 | 124460 | 11 | 7 | 22 | |
| GSE54993 | SNX20 | 124460 | 2 | 5 | 63 | |
| GSE54994 | SNX20 | 124460 | 6 | 10 | 37 | |
| GSE60625 | SNX20 | 124460 | 4 | 0 | 7 | |
| GSE74703 | SNX20 | 124460 | 2 | 4 | 30 | |
| GSE74704 | SNX20 | 124460 | 3 | 1 | 16 | |
| TCGA | SNX20 | 124460 | 25 | 12 | 59 |
Total number of gains: 99; Total number of losses: 49; Total Number of normals: 340.
Somatic mutations of SNX20:
Generating mutation plots.
Highly correlated genes for SNX20:
Showing top 20/508 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX20 | BIN2 | 0.876605 | 5 | 0 | 5 |
| SNX20 | ACAP1 | 0.851966 | 4 | 0 | 4 |
| SNX20 | PREX1 | 0.827664 | 3 | 0 | 3 |
| SNX20 | GPR65 | 0.825188 | 5 | 0 | 5 |
| SNX20 | TNFAIP8L2 | 0.823804 | 5 | 0 | 5 |
| SNX20 | NCKAP1L | 0.819186 | 6 | 0 | 5 |
| SNX20 | GRAPL | 0.81744 | 3 | 0 | 3 |
| SNX20 | PLCB2 | 0.816321 | 4 | 0 | 4 |
| SNX20 | CST7 | 0.811742 | 6 | 0 | 6 |
| SNX20 | HAVCR2 | 0.809929 | 3 | 0 | 3 |
| SNX20 | C19orf38 | 0.807921 | 3 | 0 | 3 |
| SNX20 | TNFSF8 | 0.806221 | 4 | 0 | 4 |
| SNX20 | ARHGAP9 | 0.801079 | 6 | 0 | 5 |
| SNX20 | CORO1A | 0.797304 | 7 | 0 | 6 |
| SNX20 | ST8SIA4 | 0.789766 | 6 | 0 | 6 |
| SNX20 | LCP2 | 0.788256 | 6 | 0 | 6 |
| SNX20 | EVI2B | 0.787073 | 7 | 0 | 7 |
| SNX20 | SLAMF6 | 0.784702 | 4 | 0 | 4 |
| SNX20 | INPP5D | 0.781832 | 6 | 0 | 6 |
| SNX20 | PIK3CG | 0.7805 | 5 | 0 | 4 |
For details and further investigation, click here
