| Full name: cytohesin 1 interacting protein | Alias Symbol: B3-1|HE|CYBR|CASP|CYTHIP | ||
| Type: protein-coding gene | Cytoband: 2q24.1 | ||
| Entrez ID: 9595 | HGNC ID: HGNC:9506 | Ensembl Gene: ENSG00000115165 | OMIM ID: 604448 |
| Drug and gene relationship at DGIdb | |||
Expression of CYTIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYTIP | 9595 | 209606_at | 0.3653 | 0.8239 | |
| GSE20347 | CYTIP | 9595 | 209606_at | 0.0169 | 0.9574 | |
| GSE23400 | CYTIP | 9595 | 209606_at | 0.1976 | 0.0101 | |
| GSE26886 | CYTIP | 9595 | 209606_at | 0.4007 | 0.4377 | |
| GSE29001 | CYTIP | 9595 | 209606_at | 0.1576 | 0.7129 | |
| GSE38129 | CYTIP | 9595 | 209606_at | 0.0449 | 0.9070 | |
| GSE45670 | CYTIP | 9595 | 209606_at | -0.2162 | 0.5988 | |
| GSE53622 | CYTIP | 9595 | 32387 | 0.0727 | 0.6475 | |
| GSE53624 | CYTIP | 9595 | 32387 | -0.2917 | 0.0639 | |
| GSE63941 | CYTIP | 9595 | 209606_at | -0.0144 | 0.9196 | |
| GSE77861 | CYTIP | 9595 | 209606_at | 0.1892 | 0.2407 | |
| GSE97050 | CYTIP | 9595 | A_23_P90626 | 0.8417 | 0.1748 | |
| SRP007169 | CYTIP | 9595 | RNAseq | 0.3817 | 0.6019 | |
| SRP008496 | CYTIP | 9595 | RNAseq | -0.0987 | 0.8391 | |
| SRP064894 | CYTIP | 9595 | RNAseq | 0.5940 | 0.0483 | |
| SRP133303 | CYTIP | 9595 | RNAseq | 0.2789 | 0.3418 | |
| SRP159526 | CYTIP | 9595 | RNAseq | -0.2354 | 0.8055 | |
| SRP193095 | CYTIP | 9595 | RNAseq | -0.0885 | 0.7964 | |
| SRP219564 | CYTIP | 9595 | RNAseq | 1.0212 | 0.0297 | |
| TCGA | CYTIP | 9595 | RNAseq | -0.5053 | 0.0013 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CYTIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYTIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYTIP | 9595 | 4 | 1 | 25 | |
| GSE20123 | CYTIP | 9595 | 4 | 1 | 25 | |
| GSE43470 | CYTIP | 9595 | 4 | 1 | 38 | |
| GSE46452 | CYTIP | 9595 | 1 | 4 | 54 | |
| GSE47630 | CYTIP | 9595 | 5 | 3 | 32 | |
| GSE54993 | CYTIP | 9595 | 0 | 4 | 66 | |
| GSE54994 | CYTIP | 9595 | 11 | 2 | 40 | |
| GSE60625 | CYTIP | 9595 | 0 | 3 | 8 | |
| GSE74703 | CYTIP | 9595 | 3 | 1 | 32 | |
| GSE74704 | CYTIP | 9595 | 3 | 0 | 17 | |
| TCGA | CYTIP | 9595 | 22 | 10 | 64 |
Total number of gains: 57; Total number of losses: 30; Total Number of normals: 401.
Somatic mutations of CYTIP:
Generating mutation plots.
Highly correlated genes for CYTIP:
Showing top 20/386 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYTIP | EVI2B | 0.813717 | 10 | 0 | 10 |
| CYTIP | CD53 | 0.807151 | 9 | 0 | 9 |
| CYTIP | LAPTM5 | 0.788894 | 9 | 0 | 9 |
| CYTIP | EVI2A | 0.78788 | 9 | 0 | 8 |
| CYTIP | SAMSN1 | 0.786763 | 11 | 0 | 11 |
| CYTIP | GMFG | 0.781389 | 10 | 0 | 10 |
| CYTIP | CD28 | 0.772996 | 3 | 0 | 3 |
| CYTIP | IL2RG | 0.76371 | 7 | 0 | 7 |
| CYTIP | PARVG | 0.761273 | 5 | 0 | 5 |
| CYTIP | FAM78A | 0.755981 | 3 | 0 | 3 |
| CYTIP | SNX20 | 0.752391 | 5 | 0 | 5 |
| CYTIP | RNASE6 | 0.747173 | 8 | 0 | 7 |
| CYTIP | ARHGAP9 | 0.746244 | 6 | 0 | 6 |
| CYTIP | CD48 | 0.745873 | 10 | 0 | 9 |
| CYTIP | DOCK2 | 0.743819 | 10 | 0 | 10 |
| CYTIP | SASH3 | 0.741475 | 10 | 0 | 9 |
| CYTIP | IL10RA | 0.740939 | 10 | 0 | 9 |
| CYTIP | SLA | 0.737524 | 11 | 0 | 10 |
| CYTIP | SIGLEC10 | 0.733454 | 5 | 0 | 5 |
| CYTIP | IL2RB | 0.732496 | 10 | 0 | 9 |
For details and further investigation, click here
