| Full name: ecotropic viral integration site 2A | Alias Symbol: EVDA | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 2123 | HGNC ID: HGNC:3499 | Ensembl Gene: ENSG00000126860 | OMIM ID: 158380 |
| Drug and gene relationship at DGIdb | |||
Expression of EVI2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EVI2A | 2123 | 204774_at | 0.3268 | 0.8491 | |
| GSE20347 | EVI2A | 2123 | 204774_at | -0.1235 | 0.6351 | |
| GSE23400 | EVI2A | 2123 | 204774_at | 0.2259 | 0.0072 | |
| GSE26886 | EVI2A | 2123 | 204774_at | -0.3533 | 0.3141 | |
| GSE29001 | EVI2A | 2123 | 204774_at | 0.2105 | 0.7062 | |
| GSE38129 | EVI2A | 2123 | 204774_at | -0.1079 | 0.7016 | |
| GSE45670 | EVI2A | 2123 | 204774_at | -0.6780 | 0.0548 | |
| GSE63941 | EVI2A | 2123 | 204774_at | -0.4725 | 0.1376 | |
| GSE77861 | EVI2A | 2123 | 204774_at | -0.0585 | 0.6934 | |
| GSE97050 | EVI2A | 2123 | A_23_P78092 | 0.6815 | 0.1502 | |
| SRP007169 | EVI2A | 2123 | RNAseq | 1.2329 | 0.0488 | |
| SRP008496 | EVI2A | 2123 | RNAseq | 1.0482 | 0.0230 | |
| SRP064894 | EVI2A | 2123 | RNAseq | 0.8554 | 0.0176 | |
| SRP133303 | EVI2A | 2123 | RNAseq | 0.4306 | 0.0479 | |
| SRP159526 | EVI2A | 2123 | RNAseq | -0.0464 | 0.9582 | |
| SRP193095 | EVI2A | 2123 | RNAseq | 0.0677 | 0.7444 | |
| SRP219564 | EVI2A | 2123 | RNAseq | 1.1102 | 0.0079 | |
| TCGA | EVI2A | 2123 | RNAseq | -0.0077 | 0.9605 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by EVI2A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of EVI2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EVI2A | 2123 | 7 | 3 | 20 | |
| GSE20123 | EVI2A | 2123 | 8 | 3 | 19 | |
| GSE43470 | EVI2A | 2123 | 0 | 1 | 42 | |
| GSE46452 | EVI2A | 2123 | 33 | 1 | 25 | |
| GSE47630 | EVI2A | 2123 | 7 | 1 | 32 | |
| GSE54993 | EVI2A | 2123 | 2 | 3 | 65 | |
| GSE54994 | EVI2A | 2123 | 7 | 6 | 40 | |
| GSE60625 | EVI2A | 2123 | 4 | 0 | 7 | |
| GSE74703 | EVI2A | 2123 | 0 | 1 | 35 | |
| GSE74704 | EVI2A | 2123 | 6 | 2 | 12 | |
| TCGA | EVI2A | 2123 | 20 | 10 | 66 |
Total number of gains: 94; Total number of losses: 31; Total Number of normals: 363.
Somatic mutations of EVI2A:
Generating mutation plots.
Highly correlated genes for EVI2A:
Showing top 20/280 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EVI2A | EVI2B | 0.811652 | 10 | 0 | 10 |
| EVI2A | PTPRC | 0.790135 | 9 | 0 | 9 |
| EVI2A | CD28 | 0.789635 | 3 | 0 | 3 |
| EVI2A | CYTIP | 0.78788 | 9 | 0 | 8 |
| EVI2A | CD53 | 0.781749 | 9 | 0 | 9 |
| EVI2A | CD1D | 0.760453 | 5 | 0 | 5 |
| EVI2A | GIMAP4 | 0.750125 | 8 | 0 | 8 |
| EVI2A | GIMAP2 | 0.738179 | 6 | 0 | 6 |
| EVI2A | NLRC3 | 0.734157 | 4 | 0 | 4 |
| EVI2A | SRGN | 0.728929 | 8 | 0 | 8 |
| EVI2A | FLI1 | 0.728436 | 6 | 0 | 5 |
| EVI2A | SIGLEC10 | 0.727435 | 5 | 0 | 5 |
| EVI2A | RNASE6 | 0.724035 | 10 | 0 | 9 |
| EVI2A | GIMAP6 | 0.723805 | 8 | 0 | 8 |
| EVI2A | PRKCB | 0.721455 | 6 | 0 | 5 |
| EVI2A | DOCK2 | 0.721328 | 10 | 0 | 9 |
| EVI2A | CTSS | 0.718272 | 9 | 0 | 9 |
| EVI2A | SAMSN1 | 0.716075 | 10 | 0 | 9 |
| EVI2A | C16orf54 | 0.713007 | 4 | 0 | 3 |
| EVI2A | IL10RA | 0.710238 | 10 | 0 | 9 |
For details and further investigation, click here
