| Full name: CD48 molecule | Alias Symbol: BLAST|mCD48|hCD48|SLAMF2 | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 962 | HGNC ID: HGNC:1683 | Ensembl Gene: ENSG00000117091 | OMIM ID: 109530 |
| Drug and gene relationship at DGIdb | |||
CD48 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity |
Expression of CD48:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD48 | 962 | 204118_at | 0.0112 | 0.9957 | |
| GSE20347 | CD48 | 962 | 204118_at | -0.4898 | 0.0323 | |
| GSE23400 | CD48 | 962 | 204118_at | -0.1717 | 0.0074 | |
| GSE26886 | CD48 | 962 | 204118_at | -0.5730 | 0.0500 | |
| GSE29001 | CD48 | 962 | 204118_at | -0.1595 | 0.4884 | |
| GSE38129 | CD48 | 962 | 204118_at | -0.3743 | 0.1796 | |
| GSE45670 | CD48 | 962 | 204118_at | -0.5583 | 0.0783 | |
| GSE53622 | CD48 | 962 | 5684 | -0.3306 | 0.0676 | |
| GSE53624 | CD48 | 962 | 5684 | -0.9134 | 0.0000 | |
| GSE63941 | CD48 | 962 | 204118_at | 0.0136 | 0.9419 | |
| GSE77861 | CD48 | 962 | 204118_at | -0.2861 | 0.1887 | |
| GSE97050 | CD48 | 962 | A_32_P175934 | 0.9447 | 0.1756 | |
| SRP007169 | CD48 | 962 | RNAseq | 0.2544 | 0.7444 | |
| SRP064894 | CD48 | 962 | RNAseq | 0.0109 | 0.9724 | |
| SRP133303 | CD48 | 962 | RNAseq | -0.6625 | 0.0323 | |
| SRP159526 | CD48 | 962 | RNAseq | -1.2978 | 0.1718 | |
| SRP193095 | CD48 | 962 | RNAseq | -0.4152 | 0.1453 | |
| SRP219564 | CD48 | 962 | RNAseq | 0.0833 | 0.8881 | |
| TCGA | CD48 | 962 | RNAseq | -0.1208 | 0.5342 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD48 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD48:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD48 | 962 | 10 | 0 | 20 | |
| GSE20123 | CD48 | 962 | 10 | 0 | 20 | |
| GSE43470 | CD48 | 962 | 7 | 2 | 34 | |
| GSE46452 | CD48 | 962 | 2 | 1 | 56 | |
| GSE47630 | CD48 | 962 | 14 | 0 | 26 | |
| GSE54993 | CD48 | 962 | 0 | 6 | 64 | |
| GSE54994 | CD48 | 962 | 16 | 0 | 37 | |
| GSE60625 | CD48 | 962 | 0 | 0 | 11 | |
| GSE74703 | CD48 | 962 | 7 | 2 | 27 | |
| GSE74704 | CD48 | 962 | 4 | 0 | 16 | |
| TCGA | CD48 | 962 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.
Somatic mutations of CD48:
Generating mutation plots.
Highly correlated genes for CD48:
Showing top 20/337 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD48 | EVI2B | 0.802709 | 11 | 0 | 10 |
| CD48 | CORO1A | 0.797807 | 11 | 0 | 10 |
| CD48 | CD2 | 0.797302 | 11 | 0 | 11 |
| CD48 | CD3D | 0.784232 | 12 | 0 | 11 |
| CD48 | TBC1D10C | 0.773387 | 7 | 0 | 7 |
| CD48 | SLAMF6 | 0.766925 | 5 | 0 | 4 |
| CD48 | C16orf54 | 0.764546 | 5 | 0 | 4 |
| CD48 | DOCK10 | 0.764271 | 7 | 0 | 7 |
| CD48 | BTLA | 0.764252 | 5 | 0 | 5 |
| CD48 | CD37 | 0.76387 | 9 | 0 | 8 |
| CD48 | SNX20 | 0.7631 | 6 | 0 | 6 |
| CD48 | IL10RA | 0.757543 | 12 | 0 | 12 |
| CD48 | TRAT1 | 0.756586 | 9 | 0 | 8 |
| CD48 | SPOCK2 | 0.755267 | 6 | 0 | 6 |
| CD48 | LINC01215 | 0.754461 | 5 | 0 | 5 |
| CD48 | CD53 | 0.749444 | 9 | 0 | 8 |
| CD48 | PPP1R16B | 0.749412 | 8 | 0 | 8 |
| CD48 | CYTIP | 0.745873 | 10 | 0 | 9 |
| CD48 | ARHGDIB | 0.744846 | 9 | 0 | 9 |
| CD48 | PTPRC | 0.744194 | 11 | 0 | 11 |
For details and further investigation, click here
