| Full name: adaptor related protein complex 3 subunit beta 2 | Alias Symbol: NAPTB | ||
| Type: protein-coding gene | Cytoband: 15q25.2 | ||
| Entrez ID: 8120 | HGNC ID: HGNC:567 | Ensembl Gene: ENSG00000103723 | OMIM ID: 602166 |
| Drug and gene relationship at DGIdb | |||
Expression of AP3B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AP3B2 | 8120 | 205678_at | 0.3994 | 0.5617 | |
| GSE20347 | AP3B2 | 8120 | 205678_at | 0.1378 | 0.1927 | |
| GSE23400 | AP3B2 | 8120 | 205678_at | -0.0002 | 0.9965 | |
| GSE26886 | AP3B2 | 8120 | 205678_at | 0.2409 | 0.2185 | |
| GSE29001 | AP3B2 | 8120 | 205678_at | 0.0192 | 0.8976 | |
| GSE38129 | AP3B2 | 8120 | 205678_at | 0.2280 | 0.0369 | |
| GSE45670 | AP3B2 | 8120 | 205678_at | 0.1058 | 0.4830 | |
| GSE53622 | AP3B2 | 8120 | 13271 | 0.3751 | 0.0138 | |
| GSE53624 | AP3B2 | 8120 | 13271 | 0.3161 | 0.0141 | |
| GSE63941 | AP3B2 | 8120 | 205678_at | 0.2707 | 0.7284 | |
| GSE77861 | AP3B2 | 8120 | 205678_at | 0.1012 | 0.4374 | |
| GSE97050 | AP3B2 | 8120 | A_23_P77304 | 0.0731 | 0.7858 | |
| SRP007169 | AP3B2 | 8120 | RNAseq | -1.3579 | 0.0062 | |
| SRP008496 | AP3B2 | 8120 | RNAseq | -0.7751 | 0.0424 | |
| SRP064894 | AP3B2 | 8120 | RNAseq | 1.0222 | 0.0036 | |
| SRP133303 | AP3B2 | 8120 | RNAseq | 0.1687 | 0.1664 | |
| SRP159526 | AP3B2 | 8120 | RNAseq | 1.3558 | 0.0016 | |
| SRP193095 | AP3B2 | 8120 | RNAseq | 0.2277 | 0.0935 | |
| TCGA | AP3B2 | 8120 | RNAseq | 0.2999 | 0.4571 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by AP3B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AP3B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AP3B2 | 8120 | 7 | 1 | 22 | |
| GSE20123 | AP3B2 | 8120 | 7 | 1 | 22 | |
| GSE43470 | AP3B2 | 8120 | 4 | 4 | 35 | |
| GSE46452 | AP3B2 | 8120 | 3 | 7 | 49 | |
| GSE47630 | AP3B2 | 8120 | 8 | 10 | 22 | |
| GSE54993 | AP3B2 | 8120 | 5 | 6 | 59 | |
| GSE54994 | AP3B2 | 8120 | 5 | 7 | 41 | |
| GSE60625 | AP3B2 | 8120 | 4 | 0 | 7 | |
| GSE74703 | AP3B2 | 8120 | 4 | 2 | 30 | |
| GSE74704 | AP3B2 | 8120 | 3 | 1 | 16 | |
| TCGA | AP3B2 | 8120 | 15 | 14 | 67 |
Total number of gains: 65; Total number of losses: 53; Total Number of normals: 370.
Somatic mutations of AP3B2:
Generating mutation plots.
Highly correlated genes for AP3B2:
Showing top 20/264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AP3B2 | C17orf67 | 0.862385 | 3 | 0 | 3 |
| AP3B2 | EVL | 0.836188 | 3 | 0 | 3 |
| AP3B2 | GOSR1 | 0.741013 | 3 | 0 | 3 |
| AP3B2 | USP42 | 0.740701 | 3 | 0 | 3 |
| AP3B2 | TMTC4 | 0.739919 | 3 | 0 | 3 |
| AP3B2 | PRICKLE1 | 0.739538 | 3 | 0 | 3 |
| AP3B2 | DEGS1 | 0.737594 | 3 | 0 | 3 |
| AP3B2 | GXYLT2 | 0.735494 | 3 | 0 | 3 |
| AP3B2 | MIA3 | 0.720595 | 3 | 0 | 3 |
| AP3B2 | PAMR1 | 0.714218 | 3 | 0 | 3 |
| AP3B2 | TATDN2 | 0.711433 | 3 | 0 | 3 |
| AP3B2 | CAPN12 | 0.706347 | 4 | 0 | 3 |
| AP3B2 | FBLN5 | 0.70297 | 4 | 0 | 3 |
| AP3B2 | SYNGR3 | 0.701655 | 3 | 0 | 3 |
| AP3B2 | OAF | 0.699943 | 3 | 0 | 3 |
| AP3B2 | GAS6 | 0.69932 | 5 | 0 | 4 |
| AP3B2 | SCAF4 | 0.688162 | 3 | 0 | 3 |
| AP3B2 | TMEM173 | 0.684345 | 3 | 0 | 3 |
| AP3B2 | INPP5E | 0.679363 | 5 | 0 | 4 |
| AP3B2 | DENND1A | 0.676527 | 3 | 0 | 3 |
For details and further investigation, click here
