| Full name: out at first homolog | Alias Symbol: MGC52117 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 220323 | HGNC ID: HGNC:28752 | Ensembl Gene: ENSG00000184232 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of OAF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OAF | 220323 | 225510_at | 0.3652 | 0.1316 | |
| GSE26886 | OAF | 220323 | 225510_at | 0.1010 | 0.5303 | |
| GSE45670 | OAF | 220323 | 225510_at | -0.0919 | 0.5202 | |
| GSE53622 | OAF | 220323 | 118812 | 0.3870 | 0.0010 | |
| GSE53624 | OAF | 220323 | 118812 | 0.7106 | 0.0000 | |
| GSE63941 | OAF | 220323 | 225510_at | -0.3636 | 0.2394 | |
| GSE77861 | OAF | 220323 | 225510_at | 0.2088 | 0.1420 | |
| GSE97050 | OAF | 220323 | A_24_P391586 | 0.5920 | 0.1834 | |
| SRP007169 | OAF | 220323 | RNAseq | 0.6575 | 0.2614 | |
| SRP008496 | OAF | 220323 | RNAseq | 1.0525 | 0.0078 | |
| SRP064894 | OAF | 220323 | RNAseq | 0.7422 | 0.0262 | |
| SRP133303 | OAF | 220323 | RNAseq | -0.0037 | 0.9851 | |
| SRP159526 | OAF | 220323 | RNAseq | 0.1034 | 0.7638 | |
| SRP193095 | OAF | 220323 | RNAseq | 0.9040 | 0.0027 | |
| SRP219564 | OAF | 220323 | RNAseq | 1.1338 | 0.0574 | |
| TCGA | OAF | 220323 | RNAseq | -0.0475 | 0.5176 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by OAF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OAF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OAF | 220323 | 1 | 12 | 17 | |
| GSE20123 | OAF | 220323 | 1 | 12 | 17 | |
| GSE43470 | OAF | 220323 | 2 | 8 | 33 | |
| GSE46452 | OAF | 220323 | 3 | 26 | 30 | |
| GSE47630 | OAF | 220323 | 2 | 19 | 19 | |
| GSE54993 | OAF | 220323 | 10 | 0 | 60 | |
| GSE54994 | OAF | 220323 | 5 | 19 | 29 | |
| GSE60625 | OAF | 220323 | 0 | 3 | 8 | |
| GSE74703 | OAF | 220323 | 1 | 5 | 30 | |
| GSE74704 | OAF | 220323 | 0 | 8 | 12 | |
| TCGA | OAF | 220323 | 5 | 50 | 41 |
Total number of gains: 30; Total number of losses: 162; Total Number of normals: 296.
Somatic mutations of OAF:
Generating mutation plots.
Highly correlated genes for OAF:
Showing top 20/756 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OAF | ARTN | 0.853354 | 3 | 0 | 3 |
| OAF | RBM14 | 0.81314 | 3 | 0 | 3 |
| OAF | TNFAIP1 | 0.799441 | 3 | 0 | 3 |
| OAF | TMEM132A | 0.797062 | 3 | 0 | 3 |
| OAF | EVL | 0.796009 | 3 | 0 | 3 |
| OAF | ZBED1 | 0.784301 | 3 | 0 | 3 |
| OAF | ADCY3 | 0.781918 | 3 | 0 | 3 |
| OAF | NRSN2 | 0.773312 | 3 | 0 | 3 |
| OAF | LRRC8C | 0.769187 | 3 | 0 | 3 |
| OAF | CIC | 0.768236 | 3 | 0 | 3 |
| OAF | MIER2 | 0.760442 | 3 | 0 | 3 |
| OAF | TRIM35 | 0.752599 | 3 | 0 | 3 |
| OAF | SSBP4 | 0.751501 | 3 | 0 | 3 |
| OAF | LMNB2 | 0.751125 | 3 | 0 | 3 |
| OAF | SLC38A10 | 0.751108 | 4 | 0 | 3 |
| OAF | ZCCHC3 | 0.748997 | 3 | 0 | 3 |
| OAF | SCAMP3 | 0.748108 | 3 | 0 | 3 |
| OAF | TGFB1 | 0.740608 | 3 | 0 | 3 |
| OAF | SNAPC2 | 0.737011 | 3 | 0 | 3 |
| OAF | TMEM158 | 0.734232 | 3 | 0 | 3 |
For details and further investigation, click here
