| Full name: family with sequence similarity 111 member A | Alias Symbol: FLJ22794|KIAA1895 | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 63901 | HGNC ID: HGNC:24725 | Ensembl Gene: ENSG00000166801 | OMIM ID: 615292 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM111A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM111A | 63901 | 218248_at | 0.7050 | 0.1131 | |
| GSE20347 | FAM111A | 63901 | 218248_at | 0.5483 | 0.0253 | |
| GSE23400 | FAM111A | 63901 | 218248_at | 0.3981 | 0.0000 | |
| GSE26886 | FAM111A | 63901 | 218248_at | 0.2085 | 0.3986 | |
| GSE29001 | FAM111A | 63901 | 218248_at | 0.7369 | 0.0057 | |
| GSE38129 | FAM111A | 63901 | 218248_at | 0.4513 | 0.0219 | |
| GSE45670 | FAM111A | 63901 | 218248_at | 0.3735 | 0.0754 | |
| GSE53622 | FAM111A | 63901 | 65038 | 0.6725 | 0.0000 | |
| GSE53624 | FAM111A | 63901 | 65038 | 0.5899 | 0.0000 | |
| GSE63941 | FAM111A | 63901 | 218248_at | -0.1722 | 0.8559 | |
| GSE77861 | FAM111A | 63901 | 218248_at | 0.1789 | 0.5943 | |
| GSE97050 | FAM111A | 63901 | A_24_P141629 | 0.1486 | 0.6609 | |
| SRP007169 | FAM111A | 63901 | RNAseq | 1.3618 | 0.0156 | |
| SRP008496 | FAM111A | 63901 | RNAseq | 1.1625 | 0.0010 | |
| SRP064894 | FAM111A | 63901 | RNAseq | 0.5432 | 0.0009 | |
| SRP133303 | FAM111A | 63901 | RNAseq | 0.6205 | 0.0016 | |
| SRP159526 | FAM111A | 63901 | RNAseq | 0.6720 | 0.1193 | |
| SRP193095 | FAM111A | 63901 | RNAseq | 0.4910 | 0.0003 | |
| SRP219564 | FAM111A | 63901 | RNAseq | 0.6690 | 0.0238 | |
| TCGA | FAM111A | 63901 | RNAseq | 0.0500 | 0.5007 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FAM111A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM111A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM111A | 63901 | 1 | 5 | 24 | |
| GSE20123 | FAM111A | 63901 | 1 | 5 | 24 | |
| GSE43470 | FAM111A | 63901 | 1 | 5 | 37 | |
| GSE46452 | FAM111A | 63901 | 10 | 4 | 45 | |
| GSE47630 | FAM111A | 63901 | 3 | 8 | 29 | |
| GSE54993 | FAM111A | 63901 | 3 | 0 | 67 | |
| GSE54994 | FAM111A | 63901 | 5 | 6 | 42 | |
| GSE60625 | FAM111A | 63901 | 0 | 3 | 8 | |
| GSE74703 | FAM111A | 63901 | 1 | 3 | 32 | |
| GSE74704 | FAM111A | 63901 | 1 | 4 | 15 | |
| TCGA | FAM111A | 63901 | 14 | 10 | 72 |
Total number of gains: 40; Total number of losses: 53; Total Number of normals: 395.
Somatic mutations of FAM111A:
Generating mutation plots.
Highly correlated genes for FAM111A:
Showing top 20/677 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM111A | MCOLN1 | 0.74048 | 3 | 0 | 3 |
| FAM111A | NUMA1 | 0.73769 | 3 | 0 | 3 |
| FAM111A | C12orf73 | 0.731995 | 3 | 0 | 3 |
| FAM111A | CHMP7 | 0.72986 | 3 | 0 | 3 |
| FAM111A | DPP9 | 0.729357 | 3 | 0 | 3 |
| FAM111A | ESCO1 | 0.7283 | 3 | 0 | 3 |
| FAM111A | SETD1A | 0.721621 | 3 | 0 | 3 |
| FAM111A | RSBN1L | 0.698672 | 3 | 0 | 3 |
| FAM111A | ZNF322 | 0.683997 | 3 | 0 | 3 |
| FAM111A | TGFBRAP1 | 0.680014 | 3 | 0 | 3 |
| FAM111A | ADI1 | 0.678785 | 3 | 0 | 3 |
| FAM111A | TMEM176A | 0.677599 | 3 | 0 | 3 |
| FAM111A | BCL6 | 0.67727 | 3 | 0 | 3 |
| FAM111A | COMMD7 | 0.675454 | 4 | 0 | 3 |
| FAM111A | MMS22L | 0.672877 | 3 | 0 | 3 |
| FAM111A | C1orf35 | 0.667208 | 4 | 0 | 3 |
| FAM111A | CEP170 | 0.664849 | 3 | 0 | 3 |
| FAM111A | XRN1 | 0.664642 | 4 | 0 | 3 |
| FAM111A | WDR54 | 0.661934 | 3 | 0 | 3 |
| FAM111A | GNG10 | 0.660085 | 3 | 0 | 3 |
For details and further investigation, click here
