| Full name: SET domain containing 1A, histone lysine methyltransferase | Alias Symbol: KIAA0339|Set1|KMT2F | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 9739 | HGNC ID: HGNC:29010 | Ensembl Gene: ENSG00000099381 | OMIM ID: 611052 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SETD1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SETD1A | 9739 | 213202_at | 0.4456 | 0.1418 | |
| GSE20347 | SETD1A | 9739 | 213202_at | 0.2038 | 0.0338 | |
| GSE23400 | SETD1A | 9739 | 213202_at | 0.0400 | 0.3901 | |
| GSE26886 | SETD1A | 9739 | 213202_at | 0.7839 | 0.0000 | |
| GSE29001 | SETD1A | 9739 | 213202_at | 0.0069 | 0.9722 | |
| GSE38129 | SETD1A | 9739 | 213202_at | 0.1681 | 0.0516 | |
| GSE45670 | SETD1A | 9739 | 213202_at | 0.0583 | 0.4490 | |
| GSE53622 | SETD1A | 9739 | 48089 | 0.4708 | 0.0000 | |
| GSE53624 | SETD1A | 9739 | 48089 | 0.8884 | 0.0000 | |
| GSE63941 | SETD1A | 9739 | 213202_at | 0.3423 | 0.0347 | |
| GSE77861 | SETD1A | 9739 | 213202_at | 0.2003 | 0.4366 | |
| GSE97050 | SETD1A | 9739 | A_33_P3234103 | 0.3115 | 0.2429 | |
| SRP007169 | SETD1A | 9739 | RNAseq | 1.0937 | 0.0704 | |
| SRP064894 | SETD1A | 9739 | RNAseq | 0.4155 | 0.0117 | |
| SRP133303 | SETD1A | 9739 | RNAseq | 0.3180 | 0.0314 | |
| SRP159526 | SETD1A | 9739 | RNAseq | 0.5916 | 0.0305 | |
| SRP193095 | SETD1A | 9739 | RNAseq | 0.6829 | 0.0000 | |
| SRP219564 | SETD1A | 9739 | RNAseq | 0.2398 | 0.3216 | |
| TCGA | SETD1A | 9739 | RNAseq | 0.0867 | 0.0567 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SETD1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SETD1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SETD1A | 9739 | 5 | 5 | 20 | |
| GSE20123 | SETD1A | 9739 | 5 | 4 | 21 | |
| GSE43470 | SETD1A | 9739 | 3 | 3 | 37 | |
| GSE46452 | SETD1A | 9739 | 38 | 1 | 20 | |
| GSE47630 | SETD1A | 9739 | 11 | 7 | 22 | |
| GSE54993 | SETD1A | 9739 | 2 | 5 | 63 | |
| GSE54994 | SETD1A | 9739 | 5 | 9 | 39 | |
| GSE60625 | SETD1A | 9739 | 4 | 0 | 7 | |
| GSE74703 | SETD1A | 9739 | 3 | 2 | 31 | |
| GSE74704 | SETD1A | 9739 | 3 | 2 | 15 | |
| TCGA | SETD1A | 9739 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of SETD1A:
Generating mutation plots.
Highly correlated genes for SETD1A:
Showing top 20/1313 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SETD1A | ANKIB1 | 0.772712 | 3 | 0 | 3 |
| SETD1A | PRR12 | 0.765902 | 4 | 0 | 4 |
| SETD1A | LRRC58 | 0.765534 | 3 | 0 | 3 |
| SETD1A | SCNM1 | 0.764438 | 3 | 0 | 3 |
| SETD1A | RIOK1 | 0.757371 | 4 | 0 | 4 |
| SETD1A | ACY1 | 0.755339 | 3 | 0 | 3 |
| SETD1A | RHOBTB2 | 0.755187 | 3 | 0 | 3 |
| SETD1A | MED26 | 0.743225 | 3 | 0 | 3 |
| SETD1A | ROMO1 | 0.740894 | 3 | 0 | 3 |
| SETD1A | PLCB2 | 0.738959 | 4 | 0 | 3 |
| SETD1A | B3GALT6 | 0.735561 | 5 | 0 | 5 |
| SETD1A | HAUS7 | 0.735341 | 3 | 0 | 3 |
| SETD1A | KEAP1 | 0.728394 | 3 | 0 | 3 |
| SETD1A | FTO | 0.727912 | 4 | 0 | 4 |
| SETD1A | G2E3 | 0.726829 | 3 | 0 | 3 |
| SETD1A | ABCF1 | 0.726126 | 4 | 0 | 3 |
| SETD1A | SOX13 | 0.72568 | 4 | 0 | 4 |
| SETD1A | C1orf122 | 0.724769 | 3 | 0 | 3 |
| SETD1A | DNTTIP1 | 0.724257 | 5 | 0 | 5 |
| SETD1A | PTCD1 | 0.724019 | 3 | 0 | 3 |
For details and further investigation, click here
