| Full name: prefoldin subunit 5 | Alias Symbol: PFD5|MM-1 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 5204 | HGNC ID: HGNC:8869 | Ensembl Gene: ENSG00000123349 | OMIM ID: 604899 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PFDN5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PFDN5 | 5204 | 207132_x_at | -0.5220 | 0.0553 | |
| GSE20347 | PFDN5 | 5204 | 207132_x_at | -0.4401 | 0.0001 | |
| GSE23400 | PFDN5 | 5204 | 207132_x_at | -0.3241 | 0.0000 | |
| GSE26886 | PFDN5 | 5204 | 207132_x_at | 0.2601 | 0.2774 | |
| GSE29001 | PFDN5 | 5204 | 210908_s_at | -0.5087 | 0.0679 | |
| GSE38129 | PFDN5 | 5204 | 207132_x_at | -0.4685 | 0.0001 | |
| GSE45670 | PFDN5 | 5204 | 207132_x_at | -0.4704 | 0.0000 | |
| GSE53622 | PFDN5 | 5204 | 40912 | -0.6831 | 0.0000 | |
| GSE53624 | PFDN5 | 5204 | 118981 | -0.3791 | 0.0000 | |
| GSE63941 | PFDN5 | 5204 | 210908_s_at | -0.5315 | 0.2816 | |
| GSE77861 | PFDN5 | 5204 | 207132_x_at | -0.3014 | 0.0814 | |
| GSE97050 | PFDN5 | 5204 | A_24_P181120 | -0.5956 | 0.0891 | |
| SRP007169 | PFDN5 | 5204 | RNAseq | -1.1574 | 0.0004 | |
| SRP008496 | PFDN5 | 5204 | RNAseq | -0.9627 | 0.0000 | |
| SRP064894 | PFDN5 | 5204 | RNAseq | -0.5296 | 0.0780 | |
| SRP133303 | PFDN5 | 5204 | RNAseq | -0.2806 | 0.0016 | |
| SRP159526 | PFDN5 | 5204 | RNAseq | -0.5893 | 0.0068 | |
| SRP193095 | PFDN5 | 5204 | RNAseq | -0.8529 | 0.0000 | |
| SRP219564 | PFDN5 | 5204 | RNAseq | -0.3467 | 0.2632 | |
| TCGA | PFDN5 | 5204 | RNAseq | -0.0817 | 0.0692 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PFDN5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PFDN5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PFDN5 | 5204 | 7 | 1 | 22 | |
| GSE20123 | PFDN5 | 5204 | 7 | 1 | 22 | |
| GSE43470 | PFDN5 | 5204 | 3 | 0 | 40 | |
| GSE46452 | PFDN5 | 5204 | 7 | 1 | 51 | |
| GSE47630 | PFDN5 | 5204 | 10 | 2 | 28 | |
| GSE54993 | PFDN5 | 5204 | 0 | 5 | 65 | |
| GSE54994 | PFDN5 | 5204 | 4 | 1 | 48 | |
| GSE60625 | PFDN5 | 5204 | 0 | 0 | 11 | |
| GSE74703 | PFDN5 | 5204 | 3 | 0 | 33 | |
| GSE74704 | PFDN5 | 5204 | 5 | 1 | 14 | |
| TCGA | PFDN5 | 5204 | 14 | 11 | 71 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of PFDN5:
Generating mutation plots.
Highly correlated genes for PFDN5:
Showing top 20/1289 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PFDN5 | SLTM | 0.82335 | 4 | 0 | 4 |
| PFDN5 | RSRC2 | 0.805291 | 3 | 0 | 3 |
| PFDN5 | MACROD2 | 0.784612 | 3 | 0 | 3 |
| PFDN5 | ANGPTL1 | 0.772552 | 5 | 0 | 5 |
| PFDN5 | ZNF436 | 0.770279 | 3 | 0 | 3 |
| PFDN5 | CHCHD1 | 0.767034 | 3 | 0 | 3 |
| PFDN5 | EIF4E3 | 0.760959 | 6 | 0 | 6 |
| PFDN5 | CLEC3B | 0.755781 | 3 | 0 | 3 |
| PFDN5 | BRK1 | 0.75444 | 6 | 0 | 6 |
| PFDN5 | FAM122A | 0.752369 | 3 | 0 | 3 |
| PFDN5 | LYRM7 | 0.751883 | 3 | 0 | 3 |
| PFDN5 | ZNF268 | 0.744859 | 3 | 0 | 3 |
| PFDN5 | PANK1 | 0.736095 | 3 | 0 | 3 |
| PFDN5 | RAB9B | 0.734023 | 5 | 0 | 5 |
| PFDN5 | RPS9 | 0.72851 | 10 | 0 | 9 |
| PFDN5 | SORCS1 | 0.724776 | 4 | 0 | 4 |
| PFDN5 | ICA1L | 0.723796 | 4 | 0 | 3 |
| PFDN5 | FIBIN | 0.721942 | 3 | 0 | 3 |
| PFDN5 | MRPS11 | 0.721556 | 3 | 0 | 3 |
| PFDN5 | FBXO8 | 0.718317 | 5 | 0 | 5 |
For details and further investigation, click here
