| Full name: sperm associated antigen 16 | Alias Symbol: PF20|FLJ22724|DKFZp666P1710|WDR29 | ||
| Type: protein-coding gene | Cytoband: 2q34 | ||
| Entrez ID: 79582 | HGNC ID: HGNC:23225 | Ensembl Gene: ENSG00000144451 | OMIM ID: 612173 |
| Drug and gene relationship at DGIdb | |||
Expression of SPAG16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPAG16 | 79582 | 219109_at | -1.7923 | 0.0220 | |
| GSE20347 | SPAG16 | 79582 | 219109_at | -2.0318 | 0.0000 | |
| GSE23400 | SPAG16 | 79582 | 219109_at | -0.9429 | 0.0000 | |
| GSE26886 | SPAG16 | 79582 | 219109_at | -1.4743 | 0.0000 | |
| GSE29001 | SPAG16 | 79582 | 219109_at | -1.5608 | 0.0003 | |
| GSE38129 | SPAG16 | 79582 | 219109_at | -1.5709 | 0.0000 | |
| GSE45670 | SPAG16 | 79582 | 219109_at | -1.1895 | 0.0001 | |
| GSE53622 | SPAG16 | 79582 | 143458 | -1.0394 | 0.0000 | |
| GSE53624 | SPAG16 | 79582 | 143458 | -1.5435 | 0.0000 | |
| GSE63941 | SPAG16 | 79582 | 219109_at | -0.1615 | 0.8941 | |
| GSE77861 | SPAG16 | 79582 | 219109_at | -1.8041 | 0.0060 | |
| GSE97050 | SPAG16 | 79582 | A_23_P67785 | -0.9245 | 0.0826 | |
| SRP007169 | SPAG16 | 79582 | RNAseq | -2.8730 | 0.0000 | |
| SRP008496 | SPAG16 | 79582 | RNAseq | -2.1896 | 0.0000 | |
| SRP064894 | SPAG16 | 79582 | RNAseq | -1.6943 | 0.0000 | |
| SRP133303 | SPAG16 | 79582 | RNAseq | -1.0497 | 0.0000 | |
| SRP159526 | SPAG16 | 79582 | RNAseq | -1.1655 | 0.0000 | |
| SRP193095 | SPAG16 | 79582 | RNAseq | -1.8333 | 0.0000 | |
| SRP219564 | SPAG16 | 79582 | RNAseq | -1.2013 | 0.0081 | |
| TCGA | SPAG16 | 79582 | RNAseq | -0.2970 | 0.0510 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by SPAG16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPAG16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPAG16 | 79582 | 1 | 13 | 16 | |
| GSE20123 | SPAG16 | 79582 | 1 | 13 | 16 | |
| GSE43470 | SPAG16 | 79582 | 1 | 6 | 36 | |
| GSE46452 | SPAG16 | 79582 | 0 | 5 | 54 | |
| GSE47630 | SPAG16 | 79582 | 4 | 5 | 31 | |
| GSE54993 | SPAG16 | 79582 | 0 | 3 | 67 | |
| GSE54994 | SPAG16 | 79582 | 8 | 9 | 36 | |
| GSE60625 | SPAG16 | 79582 | 0 | 3 | 8 | |
| GSE74703 | SPAG16 | 79582 | 1 | 5 | 30 | |
| GSE74704 | SPAG16 | 79582 | 1 | 7 | 12 | |
| TCGA | SPAG16 | 79582 | 13 | 27 | 56 |
Total number of gains: 30; Total number of losses: 96; Total Number of normals: 362.
Somatic mutations of SPAG16:
Generating mutation plots.
Highly correlated genes for SPAG16:
Showing top 20/1928 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPAG16 | FAM122A | 0.88007 | 3 | 0 | 3 |
| SPAG16 | GBP6 | 0.835252 | 4 | 0 | 4 |
| SPAG16 | SNORA68 | 0.8351 | 4 | 0 | 4 |
| SPAG16 | CCNYL1 | 0.807242 | 5 | 0 | 5 |
| SPAG16 | FBXO3 | 0.793873 | 10 | 0 | 10 |
| SPAG16 | IMPACT | 0.789684 | 3 | 0 | 3 |
| SPAG16 | RBM20 | 0.780748 | 4 | 0 | 4 |
| SPAG16 | RAB21 | 0.776696 | 3 | 0 | 3 |
| SPAG16 | MPP7 | 0.77477 | 7 | 0 | 6 |
| SPAG16 | HDHD2 | 0.774027 | 5 | 0 | 5 |
| SPAG16 | GPD1L | 0.773744 | 11 | 0 | 11 |
| SPAG16 | HPGD | 0.772943 | 11 | 0 | 11 |
| SPAG16 | ATF7 | 0.772229 | 3 | 0 | 3 |
| SPAG16 | SFTA2 | 0.771803 | 4 | 0 | 4 |
| SPAG16 | EPB41L4A | 0.768216 | 8 | 0 | 8 |
| SPAG16 | FCHO2 | 0.766869 | 7 | 0 | 6 |
| SPAG16 | HBP1 | 0.763348 | 9 | 0 | 9 |
| SPAG16 | GALNT12 | 0.763297 | 11 | 0 | 11 |
| SPAG16 | ZNF585A | 0.762508 | 4 | 0 | 4 |
| SPAG16 | ACOX3 | 0.759814 | 10 | 0 | 10 |
For details and further investigation, click here
