| Full name: family with sequence similarity 169 member A | Alias Symbol: KIAA0888|SLAP75 | ||
| Type: protein-coding gene | Cytoband: 5q13.3 | ||
| Entrez ID: 26049 | HGNC ID: HGNC:29138 | Ensembl Gene: ENSG00000198780 | OMIM ID: 615769 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM169A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM169A | 26049 | 235048_at | 1.1703 | 0.2761 | |
| GSE20347 | FAM169A | 26049 | 213954_at | 0.7063 | 0.0006 | |
| GSE23400 | FAM169A | 26049 | 213954_at | 0.1023 | 0.0006 | |
| GSE26886 | FAM169A | 26049 | 235048_at | 1.6007 | 0.0032 | |
| GSE29001 | FAM169A | 26049 | 213954_at | 0.7434 | 0.1021 | |
| GSE38129 | FAM169A | 26049 | 213954_at | 0.7148 | 0.0014 | |
| GSE45670 | FAM169A | 26049 | 235048_at | 1.0863 | 0.0094 | |
| GSE53622 | FAM169A | 26049 | 6014 | 0.9302 | 0.0000 | |
| GSE53624 | FAM169A | 26049 | 6014 | 0.9963 | 0.0000 | |
| GSE63941 | FAM169A | 26049 | 235048_at | 2.9092 | 0.0120 | |
| GSE77861 | FAM169A | 26049 | 235048_at | 1.1282 | 0.0109 | |
| GSE97050 | FAM169A | 26049 | A_23_P423074 | 0.3326 | 0.3357 | |
| SRP007169 | FAM169A | 26049 | RNAseq | 2.9370 | 0.0000 | |
| SRP133303 | FAM169A | 26049 | RNAseq | 1.2475 | 0.0019 | |
| SRP159526 | FAM169A | 26049 | RNAseq | 2.6847 | 0.0000 | |
| SRP193095 | FAM169A | 26049 | RNAseq | 1.2307 | 0.0000 | |
| TCGA | FAM169A | 26049 | RNAseq | 0.2033 | 0.2194 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by FAM169A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM169A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM169A | 26049 | 1 | 13 | 16 | |
| GSE20123 | FAM169A | 26049 | 1 | 13 | 16 | |
| GSE43470 | FAM169A | 26049 | 1 | 13 | 29 | |
| GSE46452 | FAM169A | 26049 | 0 | 28 | 31 | |
| GSE47630 | FAM169A | 26049 | 1 | 19 | 20 | |
| GSE54993 | FAM169A | 26049 | 8 | 1 | 61 | |
| GSE54994 | FAM169A | 26049 | 1 | 19 | 33 | |
| GSE60625 | FAM169A | 26049 | 0 | 0 | 11 | |
| GSE74703 | FAM169A | 26049 | 1 | 9 | 26 | |
| GSE74704 | FAM169A | 26049 | 1 | 6 | 13 | |
| TCGA | FAM169A | 26049 | 4 | 50 | 42 |
Total number of gains: 19; Total number of losses: 171; Total Number of normals: 298.
Somatic mutations of FAM169A:
Generating mutation plots.
Highly correlated genes for FAM169A:
Showing top 20/1277 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM169A | ZFHX3 | 0.787216 | 3 | 0 | 3 |
| FAM169A | TMEM60 | 0.784099 | 3 | 0 | 3 |
| FAM169A | EXOSC6 | 0.778249 | 3 | 0 | 3 |
| FAM169A | A4GALT | 0.77755 | 3 | 0 | 3 |
| FAM169A | AFAP1L2 | 0.762531 | 3 | 0 | 3 |
| FAM169A | ERVW-1 | 0.759917 | 3 | 0 | 3 |
| FAM169A | SESN3 | 0.750195 | 3 | 0 | 3 |
| FAM169A | SLC30A6 | 0.735283 | 4 | 0 | 4 |
| FAM169A | SYNE2 | 0.730377 | 3 | 0 | 3 |
| FAM169A | RNF26 | 0.730157 | 3 | 0 | 3 |
| FAM169A | YWHAG | 0.728986 | 4 | 0 | 4 |
| FAM169A | CWF19L2 | 0.727984 | 3 | 0 | 3 |
| FAM169A | GATAD2B | 0.721912 | 3 | 0 | 3 |
| FAM169A | NGF | 0.721473 | 3 | 0 | 3 |
| FAM169A | NOL9 | 0.716267 | 3 | 0 | 3 |
| FAM169A | DPM1 | 0.712348 | 3 | 0 | 3 |
| FAM169A | CEP120 | 0.709182 | 3 | 0 | 3 |
| FAM169A | SRXN1 | 0.708648 | 4 | 0 | 4 |
| FAM169A | FOXN2 | 0.708435 | 6 | 0 | 5 |
| FAM169A | BLACAT1 | 0.706451 | 4 | 0 | 4 |
For details and further investigation, click here
