| Full name: alpha 1,4-galactosyltransferase (P blood group) | Alias Symbol: A14GALT|Gb3S|P(k) | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 53947 | HGNC ID: HGNC:18149 | Ensembl Gene: ENSG00000128274 | OMIM ID: 607922 |
| Drug and gene relationship at DGIdb | |||
Expression of A4GALT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | A4GALT | 53947 | 219488_at | 0.2779 | 0.2503 | |
| GSE20347 | A4GALT | 53947 | 219488_at | 0.0191 | 0.8675 | |
| GSE23400 | A4GALT | 53947 | 219488_at | -0.0178 | 0.7565 | |
| GSE26886 | A4GALT | 53947 | 219488_at | 0.6016 | 0.0000 | |
| GSE29001 | A4GALT | 53947 | 219488_at | 0.0261 | 0.9284 | |
| GSE38129 | A4GALT | 53947 | 219488_at | 0.0163 | 0.8823 | |
| GSE45670 | A4GALT | 53947 | 219488_at | 0.0998 | 0.5695 | |
| GSE53622 | A4GALT | 53947 | 7238 | 0.1353 | 0.1192 | |
| GSE53624 | A4GALT | 53947 | 7238 | 0.3967 | 0.0000 | |
| GSE63941 | A4GALT | 53947 | 219488_at | 0.0430 | 0.8805 | |
| GSE77861 | A4GALT | 53947 | 219488_at | 0.0809 | 0.7287 | |
| GSE97050 | A4GALT | 53947 | A_33_P3294002 | 0.1583 | 0.5385 | |
| SRP007169 | A4GALT | 53947 | RNAseq | 1.0428 | 0.1050 | |
| SRP008496 | A4GALT | 53947 | RNAseq | 0.7374 | 0.0914 | |
| SRP064894 | A4GALT | 53947 | RNAseq | 0.2484 | 0.3456 | |
| SRP133303 | A4GALT | 53947 | RNAseq | 0.3013 | 0.0626 | |
| SRP159526 | A4GALT | 53947 | RNAseq | 1.0056 | 0.0455 | |
| SRP193095 | A4GALT | 53947 | RNAseq | 0.6965 | 0.0000 | |
| SRP219564 | A4GALT | 53947 | RNAseq | 0.4729 | 0.0579 | |
| TCGA | A4GALT | 53947 | RNAseq | 0.1210 | 0.2826 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by A4GALT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of A4GALT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | A4GALT | 53947 | 6 | 6 | 18 | |
| GSE20123 | A4GALT | 53947 | 6 | 5 | 19 | |
| GSE43470 | A4GALT | 53947 | 4 | 6 | 33 | |
| GSE46452 | A4GALT | 53947 | 31 | 2 | 26 | |
| GSE47630 | A4GALT | 53947 | 9 | 4 | 27 | |
| GSE54993 | A4GALT | 53947 | 3 | 6 | 61 | |
| GSE54994 | A4GALT | 53947 | 11 | 8 | 34 | |
| GSE60625 | A4GALT | 53947 | 5 | 0 | 6 | |
| GSE74703 | A4GALT | 53947 | 4 | 4 | 28 | |
| GSE74704 | A4GALT | 53947 | 3 | 3 | 14 | |
| TCGA | A4GALT | 53947 | 27 | 14 | 55 |
Total number of gains: 109; Total number of losses: 58; Total Number of normals: 321.
Somatic mutations of A4GALT:
Generating mutation plots.
Highly correlated genes for A4GALT:
Showing top 20/481 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| A4GALT | ITGA3 | 0.832884 | 3 | 0 | 3 |
| A4GALT | MAP4K2 | 0.815922 | 4 | 0 | 4 |
| A4GALT | CHST12 | 0.804764 | 3 | 0 | 3 |
| A4GALT | DDX54 | 0.80263 | 3 | 0 | 3 |
| A4GALT | RSRC1 | 0.795103 | 3 | 0 | 3 |
| A4GALT | GOLIM4 | 0.789549 | 3 | 0 | 3 |
| A4GALT | CPSF3 | 0.787709 | 3 | 0 | 3 |
| A4GALT | EIF5A2 | 0.782455 | 3 | 0 | 3 |
| A4GALT | WDR54 | 0.778693 | 3 | 0 | 3 |
| A4GALT | DGUOK | 0.778438 | 3 | 0 | 3 |
| A4GALT | MYO5A | 0.778352 | 3 | 0 | 3 |
| A4GALT | FAM169A | 0.77755 | 3 | 0 | 3 |
| A4GALT | C11orf24 | 0.776636 | 3 | 0 | 3 |
| A4GALT | LARP6 | 0.775666 | 3 | 0 | 3 |
| A4GALT | RRAS2 | 0.772843 | 3 | 0 | 3 |
| A4GALT | PPFIA1 | 0.767764 | 3 | 0 | 3 |
| A4GALT | PTPN2 | 0.765215 | 3 | 0 | 3 |
| A4GALT | NGF | 0.763416 | 3 | 0 | 3 |
| A4GALT | LCLAT1 | 0.762099 | 3 | 0 | 3 |
| A4GALT | BRCA1 | 0.761295 | 3 | 0 | 3 |
For details and further investigation, click here
