| Full name: actin filament associated protein 1 like 2 | Alias Symbol: FLJ14564|Em:AC005383.4|XB130 | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 84632 | HGNC ID: HGNC:25901 | Ensembl Gene: ENSG00000169129 | OMIM ID: 612420 |
| Drug and gene relationship at DGIdb | |||
Expression of AFAP1L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AFAP1L2 | 84632 | 226829_at | -0.1553 | 0.9135 | |
| GSE26886 | AFAP1L2 | 84632 | 226829_at | 0.0006 | 0.9993 | |
| GSE45670 | AFAP1L2 | 84632 | 226829_at | 0.3122 | 0.3482 | |
| GSE53622 | AFAP1L2 | 84632 | 96537 | 0.1548 | 0.2600 | |
| GSE53624 | AFAP1L2 | 84632 | 96537 | -0.3525 | 0.0060 | |
| GSE63941 | AFAP1L2 | 84632 | 226829_at | 1.9200 | 0.1284 | |
| GSE77861 | AFAP1L2 | 84632 | 226829_at | 0.6427 | 0.1556 | |
| GSE97050 | AFAP1L2 | 84632 | A_23_P406341 | 0.3952 | 0.3279 | |
| SRP007169 | AFAP1L2 | 84632 | RNAseq | 0.5926 | 0.3923 | |
| SRP008496 | AFAP1L2 | 84632 | RNAseq | 0.1842 | 0.6861 | |
| SRP064894 | AFAP1L2 | 84632 | RNAseq | -0.0020 | 0.9931 | |
| SRP133303 | AFAP1L2 | 84632 | RNAseq | 1.0243 | 0.0097 | |
| SRP159526 | AFAP1L2 | 84632 | RNAseq | -0.5346 | 0.1991 | |
| SRP193095 | AFAP1L2 | 84632 | RNAseq | 0.2881 | 0.2312 | |
| SRP219564 | AFAP1L2 | 84632 | RNAseq | -0.0217 | 0.9702 | |
| TCGA | AFAP1L2 | 84632 | RNAseq | 0.2711 | 0.0279 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by AFAP1L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AFAP1L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AFAP1L2 | 84632 | 2 | 8 | 20 | |
| GSE20123 | AFAP1L2 | 84632 | 2 | 7 | 21 | |
| GSE43470 | AFAP1L2 | 84632 | 0 | 9 | 34 | |
| GSE46452 | AFAP1L2 | 84632 | 0 | 11 | 48 | |
| GSE47630 | AFAP1L2 | 84632 | 2 | 14 | 24 | |
| GSE54993 | AFAP1L2 | 84632 | 8 | 0 | 62 | |
| GSE54994 | AFAP1L2 | 84632 | 1 | 9 | 43 | |
| GSE60625 | AFAP1L2 | 84632 | 0 | 0 | 11 | |
| GSE74703 | AFAP1L2 | 84632 | 0 | 6 | 30 | |
| GSE74704 | AFAP1L2 | 84632 | 1 | 3 | 16 | |
| TCGA | AFAP1L2 | 84632 | 4 | 28 | 64 |
Total number of gains: 20; Total number of losses: 95; Total Number of normals: 373.
Somatic mutations of AFAP1L2:
Generating mutation plots.
Highly correlated genes for AFAP1L2:
Showing top 20/307 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AFAP1L2 | PLEKHA8 | 0.849483 | 3 | 0 | 3 |
| AFAP1L2 | TMEM60 | 0.79626 | 3 | 0 | 3 |
| AFAP1L2 | AHR | 0.76628 | 3 | 0 | 3 |
| AFAP1L2 | FAM169A | 0.762531 | 3 | 0 | 3 |
| AFAP1L2 | ELF4 | 0.74437 | 3 | 0 | 3 |
| AFAP1L2 | PHF14 | 0.743286 | 3 | 0 | 3 |
| AFAP1L2 | LRRC8A | 0.740775 | 3 | 0 | 3 |
| AFAP1L2 | MCM6 | 0.739834 | 3 | 0 | 3 |
| AFAP1L2 | ACYP1 | 0.737278 | 4 | 0 | 3 |
| AFAP1L2 | TWSG1 | 0.733893 | 3 | 0 | 3 |
| AFAP1L2 | TTC4 | 0.730279 | 3 | 0 | 3 |
| AFAP1L2 | CHD2 | 0.728322 | 3 | 0 | 3 |
| AFAP1L2 | NCAPD2 | 0.724227 | 3 | 0 | 3 |
| AFAP1L2 | SNRPA1 | 0.720625 | 3 | 0 | 3 |
| AFAP1L2 | SCAMP1 | 0.718238 | 3 | 0 | 3 |
| AFAP1L2 | RFC3 | 0.716136 | 3 | 0 | 3 |
| AFAP1L2 | DUSP6 | 0.716129 | 4 | 0 | 4 |
| AFAP1L2 | ARL6IP6 | 0.713805 | 4 | 0 | 4 |
| AFAP1L2 | MPZL1 | 0.7092 | 3 | 0 | 3 |
| AFAP1L2 | MRPL32 | 0.70751 | 3 | 0 | 3 |
For details and further investigation, click here
