| Full name: cordon-bleu WH2 repeat protein like 1 | Alias Symbol: KIAA0977 | ||
| Type: protein-coding gene | Cytoband: 2q24.3 | ||
| Entrez ID: 22837 | HGNC ID: HGNC:23571 | Ensembl Gene: ENSG00000082438 | OMIM ID: 610318 |
| Drug and gene relationship at DGIdb | |||
Expression of COBLL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COBLL1 | 22837 | 203642_s_at | -0.7618 | 0.2879 | |
| GSE20347 | COBLL1 | 22837 | 203642_s_at | -1.4056 | 0.0000 | |
| GSE23400 | COBLL1 | 22837 | 203642_s_at | -1.0407 | 0.0000 | |
| GSE26886 | COBLL1 | 22837 | 203642_s_at | -2.3020 | 0.0000 | |
| GSE29001 | COBLL1 | 22837 | 203642_s_at | -0.8598 | 0.1080 | |
| GSE38129 | COBLL1 | 22837 | 203642_s_at | -1.2162 | 0.0000 | |
| GSE45670 | COBLL1 | 22837 | 203642_s_at | -0.5517 | 0.0528 | |
| GSE53622 | COBLL1 | 22837 | 94561 | -1.1133 | 0.0000 | |
| GSE53624 | COBLL1 | 22837 | 85089 | -1.4410 | 0.0000 | |
| GSE63941 | COBLL1 | 22837 | 203642_s_at | -0.7131 | 0.2620 | |
| GSE77861 | COBLL1 | 22837 | 203642_s_at | -1.5119 | 0.0065 | |
| GSE97050 | COBLL1 | 22837 | A_33_P3238215 | -0.8030 | 0.0781 | |
| SRP007169 | COBLL1 | 22837 | RNAseq | -2.0982 | 0.0003 | |
| SRP008496 | COBLL1 | 22837 | RNAseq | -1.8647 | 0.0000 | |
| SRP064894 | COBLL1 | 22837 | RNAseq | -1.8565 | 0.0000 | |
| SRP133303 | COBLL1 | 22837 | RNAseq | -0.4880 | 0.0323 | |
| SRP159526 | COBLL1 | 22837 | RNAseq | -1.2599 | 0.0145 | |
| SRP193095 | COBLL1 | 22837 | RNAseq | -1.0178 | 0.0000 | |
| SRP219564 | COBLL1 | 22837 | RNAseq | -1.3014 | 0.0127 | |
| TCGA | COBLL1 | 22837 | RNAseq | -0.3772 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by COBLL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COBLL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COBLL1 | 22837 | 6 | 1 | 23 | |
| GSE20123 | COBLL1 | 22837 | 6 | 1 | 23 | |
| GSE43470 | COBLL1 | 22837 | 7 | 1 | 35 | |
| GSE46452 | COBLL1 | 22837 | 1 | 4 | 54 | |
| GSE47630 | COBLL1 | 22837 | 5 | 3 | 32 | |
| GSE54993 | COBLL1 | 22837 | 0 | 5 | 65 | |
| GSE54994 | COBLL1 | 22837 | 11 | 2 | 40 | |
| GSE60625 | COBLL1 | 22837 | 0 | 3 | 8 | |
| GSE74703 | COBLL1 | 22837 | 5 | 1 | 30 | |
| GSE74704 | COBLL1 | 22837 | 3 | 0 | 17 | |
| TCGA | COBLL1 | 22837 | 25 | 8 | 63 |
Total number of gains: 69; Total number of losses: 29; Total Number of normals: 390.
Somatic mutations of COBLL1:
Generating mutation plots.
Highly correlated genes for COBLL1:
Showing top 20/1711 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COBLL1 | HDHD2 | 0.819079 | 4 | 0 | 4 |
| COBLL1 | VSIG10L | 0.808306 | 6 | 0 | 6 |
| COBLL1 | CCNYL1 | 0.800218 | 5 | 0 | 5 |
| COBLL1 | MUC15 | 0.795825 | 6 | 0 | 6 |
| COBLL1 | TAB3 | 0.791221 | 6 | 0 | 6 |
| COBLL1 | CYSRT1 | 0.788627 | 6 | 0 | 6 |
| COBLL1 | TYSND1 | 0.781164 | 3 | 0 | 3 |
| COBLL1 | TP53INP2 | 0.779735 | 5 | 0 | 5 |
| COBLL1 | HPGD | 0.777537 | 10 | 0 | 10 |
| COBLL1 | FAM174A | 0.77337 | 7 | 0 | 7 |
| COBLL1 | TMPRSS11B | 0.773039 | 6 | 0 | 6 |
| COBLL1 | COG6 | 0.772115 | 3 | 0 | 3 |
| COBLL1 | C5orf66-AS1 | 0.770051 | 5 | 0 | 5 |
| COBLL1 | ZNF416 | 0.767633 | 4 | 0 | 4 |
| COBLL1 | FAM3B | 0.76741 | 5 | 0 | 5 |
| COBLL1 | LMO4 | 0.762762 | 3 | 0 | 3 |
| COBLL1 | EMP1 | 0.760951 | 10 | 0 | 10 |
| COBLL1 | TMPRSS11E | 0.760872 | 10 | 0 | 10 |
| COBLL1 | EIF3J | 0.760828 | 3 | 0 | 3 |
| COBLL1 | SPINK5 | 0.760327 | 10 | 0 | 10 |
For details and further investigation, click here
