| Full name: periaxin | Alias Symbol: KIAA1620 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 57716 | HGNC ID: HGNC:13797 | Ensembl Gene: ENSG00000105227 | OMIM ID: 605725 |
| Drug and gene relationship at DGIdb | |||
Expression of PRX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRX | 57716 | 220024_s_at | -0.0946 | 0.7812 | |
| GSE20347 | PRX | 57716 | 220024_s_at | -0.0387 | 0.6507 | |
| GSE23400 | PRX | 57716 | 220024_s_at | -0.1637 | 0.0001 | |
| GSE26886 | PRX | 57716 | 220024_s_at | 0.3593 | 0.0050 | |
| GSE29001 | PRX | 57716 | 220024_s_at | -0.0311 | 0.9017 | |
| GSE38129 | PRX | 57716 | 220024_s_at | -0.2230 | 0.0284 | |
| GSE45670 | PRX | 57716 | 220024_s_at | -0.0692 | 0.4026 | |
| GSE53622 | PRX | 57716 | 2320 | -0.7267 | 0.0000 | |
| GSE53624 | PRX | 57716 | 2320 | -0.1537 | 0.1938 | |
| GSE63941 | PRX | 57716 | 220024_s_at | 0.0528 | 0.7446 | |
| GSE77861 | PRX | 57716 | 220024_s_at | -0.0727 | 0.7052 | |
| SRP064894 | PRX | 57716 | RNAseq | 0.5592 | 0.0868 | |
| SRP133303 | PRX | 57716 | RNAseq | -0.5472 | 0.0668 | |
| SRP159526 | PRX | 57716 | RNAseq | -0.1828 | 0.6005 | |
| SRP193095 | PRX | 57716 | RNAseq | -0.1473 | 0.4164 | |
| SRP219564 | PRX | 57716 | RNAseq | -0.3551 | 0.5414 | |
| TCGA | PRX | 57716 | RNAseq | -0.7028 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRX | 57716 | 6 | 5 | 19 | |
| GSE20123 | PRX | 57716 | 6 | 4 | 20 | |
| GSE43470 | PRX | 57716 | 3 | 9 | 31 | |
| GSE46452 | PRX | 57716 | 48 | 1 | 10 | |
| GSE47630 | PRX | 57716 | 9 | 5 | 26 | |
| GSE54993 | PRX | 57716 | 17 | 3 | 50 | |
| GSE54994 | PRX | 57716 | 8 | 9 | 36 | |
| GSE60625 | PRX | 57716 | 9 | 0 | 2 | |
| GSE74703 | PRX | 57716 | 3 | 6 | 27 | |
| GSE74704 | PRX | 57716 | 6 | 2 | 12 | |
| TCGA | PRX | 57716 | 14 | 16 | 66 |
Total number of gains: 129; Total number of losses: 60; Total Number of normals: 299.
Somatic mutations of PRX:
Generating mutation plots.
Highly correlated genes for PRX:
Showing top 20/758 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRX | ZNF574 | 0.742918 | 3 | 0 | 3 |
| PRX | OR10H1 | 0.714169 | 4 | 0 | 4 |
| PRX | NOX1 | 0.714032 | 5 | 0 | 5 |
| PRX | PRR34 | 0.706375 | 4 | 0 | 4 |
| PRX | BCAS4 | 0.701367 | 3 | 0 | 3 |
| PRX | COL26A1 | 0.697959 | 3 | 0 | 3 |
| PRX | FAM99B | 0.696037 | 3 | 0 | 3 |
| PRX | MAST1 | 0.69491 | 3 | 0 | 3 |
| PRX | KLK14 | 0.692701 | 4 | 0 | 3 |
| PRX | CELF3 | 0.690473 | 7 | 0 | 7 |
| PRX | INHA | 0.688961 | 3 | 0 | 3 |
| PRX | SMR3B | 0.68803 | 3 | 0 | 3 |
| PRX | KCNC4 | 0.684271 | 5 | 0 | 5 |
| PRX | LINC00598 | 0.683963 | 3 | 0 | 3 |
| PRX | NSMF | 0.68373 | 3 | 0 | 3 |
| PRX | TRMT61A | 0.682921 | 3 | 0 | 3 |
| PRX | DAB1 | 0.681409 | 3 | 0 | 3 |
| PRX | KLC1 | 0.68028 | 3 | 0 | 3 |
| PRX | SHARPIN | 0.679732 | 3 | 0 | 3 |
| PRX | ZNF771 | 0.676625 | 4 | 0 | 3 |
For details and further investigation, click here
