| Full name: keratin associated protein 1-1 | Alias Symbol: KAP1.1B|HB2A|KAP1.1|KAP1.1A | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 81851 | HGNC ID: HGNC:16772 | Ensembl Gene: ENSG00000188581 | OMIM ID: 608819 |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP1-1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRTAP1-1 | 81851 | 220976_s_at | -0.0028 | 0.9930 | |
| GSE20347 | KRTAP1-1 | 81851 | 220976_s_at | -0.0438 | 0.4841 | |
| GSE23400 | KRTAP1-1 | 81851 | 220976_s_at | -0.0183 | 0.5826 | |
| GSE26886 | KRTAP1-1 | 81851 | 220976_s_at | 0.2447 | 0.4256 | |
| GSE29001 | KRTAP1-1 | 81851 | 220976_s_at | -0.1484 | 0.5450 | |
| GSE38129 | KRTAP1-1 | 81851 | 220976_s_at | -0.0928 | 0.1028 | |
| GSE45670 | KRTAP1-1 | 81851 | 220976_s_at | -0.0285 | 0.8017 | |
| GSE53622 | KRTAP1-1 | 81851 | 101358 | -0.4771 | 0.0006 | |
| GSE53624 | KRTAP1-1 | 81851 | 101358 | -0.5122 | 0.0000 | |
| GSE63941 | KRTAP1-1 | 81851 | 220976_s_at | -0.3939 | 0.1714 | |
| GSE77861 | KRTAP1-1 | 81851 | 220976_s_at | -0.0482 | 0.6163 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP1-1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP1-1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP1-1 | 81851 | 7 | 1 | 22 | |
| GSE20123 | KRTAP1-1 | 81851 | 7 | 1 | 22 | |
| GSE43470 | KRTAP1-1 | 81851 | 1 | 2 | 40 | |
| GSE46452 | KRTAP1-1 | 81851 | 34 | 0 | 25 | |
| GSE47630 | KRTAP1-1 | 81851 | 8 | 1 | 31 | |
| GSE54993 | KRTAP1-1 | 81851 | 3 | 4 | 63 | |
| GSE54994 | KRTAP1-1 | 81851 | 8 | 5 | 40 | |
| GSE60625 | KRTAP1-1 | 81851 | 4 | 0 | 7 | |
| GSE74703 | KRTAP1-1 | 81851 | 1 | 1 | 34 | |
| GSE74704 | KRTAP1-1 | 81851 | 4 | 1 | 15 |
Total number of gains: 77; Total number of losses: 16; Total Number of normals: 299.
Somatic mutations of KRTAP1-1:
Generating mutation plots.
Highly correlated genes for KRTAP1-1:
Showing top 20/414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP1-1 | PAQR9 | 0.743698 | 3 | 0 | 3 |
| KRTAP1-1 | LINC00475 | 0.715039 | 3 | 0 | 3 |
| KRTAP1-1 | FAM186A | 0.699056 | 3 | 0 | 3 |
| KRTAP1-1 | GATA3-AS1 | 0.697113 | 3 | 0 | 3 |
| KRTAP1-1 | OR2H2 | 0.689166 | 5 | 0 | 5 |
| KRTAP1-1 | B3GALT1 | 0.684082 | 3 | 0 | 3 |
| KRTAP1-1 | ZFHX4-AS1 | 0.676302 | 3 | 0 | 3 |
| KRTAP1-1 | FOXN3-AS2 | 0.675463 | 6 | 0 | 6 |
| KRTAP1-1 | C4BPB | 0.663916 | 5 | 0 | 5 |
| KRTAP1-1 | OR5I1 | 0.663835 | 5 | 0 | 5 |
| KRTAP1-1 | EDA2R | 0.652352 | 5 | 0 | 5 |
| KRTAP1-1 | NOS1 | 0.647863 | 5 | 0 | 4 |
| KRTAP1-1 | CDC25C | 0.647306 | 3 | 0 | 3 |
| KRTAP1-1 | ARHGEF38 | 0.647146 | 6 | 0 | 5 |
| KRTAP1-1 | SLCO1C1 | 0.64166 | 4 | 0 | 4 |
| KRTAP1-1 | CETP | 0.636171 | 5 | 0 | 5 |
| KRTAP1-1 | FN3K | 0.63397 | 5 | 0 | 5 |
| KRTAP1-1 | PPM1E | 0.632831 | 3 | 0 | 3 |
| KRTAP1-1 | HAO1 | 0.631126 | 4 | 0 | 4 |
| KRTAP1-1 | ASPA | 0.626569 | 3 | 0 | 3 |
For details and further investigation, click here
