| Full name: calpain small subunit 1 | Alias Symbol: CANP|CANPS|30K|CDPS | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 826 | HGNC ID: HGNC:1481 | Ensembl Gene: ENSG00000126247 | OMIM ID: 114170 |
| Drug and gene relationship at DGIdb | |||
Expression of CAPNS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPNS1 | 826 | 200001_at | -0.6186 | 0.1221 | |
| GSE20347 | CAPNS1 | 826 | 200001_at | -1.2403 | 0.0000 | |
| GSE23400 | CAPNS1 | 826 | 200001_at | -0.6322 | 0.0000 | |
| GSE26886 | CAPNS1 | 826 | 200001_at | -1.5416 | 0.0001 | |
| GSE29001 | CAPNS1 | 826 | 200001_at | -1.2846 | 0.0016 | |
| GSE38129 | CAPNS1 | 826 | 200001_at | -0.7768 | 0.0000 | |
| GSE45670 | CAPNS1 | 826 | 200001_at | -0.6325 | 0.0014 | |
| GSE53622 | CAPNS1 | 826 | 153620 | -0.8239 | 0.0000 | |
| GSE53624 | CAPNS1 | 826 | 153620 | -0.7388 | 0.0000 | |
| GSE63941 | CAPNS1 | 826 | 200001_at | 1.2563 | 0.0349 | |
| GSE77861 | CAPNS1 | 826 | 200001_at | -0.4862 | 0.0659 | |
| GSE97050 | CAPNS1 | 826 | A_23_P67648 | -0.1939 | 0.6088 | |
| SRP007169 | CAPNS1 | 826 | RNAseq | -1.3331 | 0.0063 | |
| SRP008496 | CAPNS1 | 826 | RNAseq | -1.8621 | 0.0000 | |
| SRP064894 | CAPNS1 | 826 | RNAseq | -0.3641 | 0.1871 | |
| SRP133303 | CAPNS1 | 826 | RNAseq | -0.6609 | 0.0047 | |
| SRP159526 | CAPNS1 | 826 | RNAseq | -0.9318 | 0.0013 | |
| SRP193095 | CAPNS1 | 826 | RNAseq | -1.0675 | 0.0000 | |
| SRP219564 | CAPNS1 | 826 | RNAseq | -1.0024 | 0.0055 | |
| TCGA | CAPNS1 | 826 | RNAseq | 0.0347 | 0.4622 |
Upregulated datasets: 1; Downregulated datasets: 7.
Survival by CAPNS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAPNS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPNS1 | 826 | 8 | 4 | 18 | |
| GSE20123 | CAPNS1 | 826 | 8 | 3 | 19 | |
| GSE43470 | CAPNS1 | 826 | 3 | 7 | 33 | |
| GSE46452 | CAPNS1 | 826 | 48 | 1 | 10 | |
| GSE47630 | CAPNS1 | 826 | 9 | 5 | 26 | |
| GSE54993 | CAPNS1 | 826 | 17 | 3 | 50 | |
| GSE54994 | CAPNS1 | 826 | 6 | 9 | 38 | |
| GSE60625 | CAPNS1 | 826 | 9 | 0 | 2 | |
| GSE74703 | CAPNS1 | 826 | 3 | 4 | 29 | |
| GSE74704 | CAPNS1 | 826 | 7 | 1 | 12 | |
| TCGA | CAPNS1 | 826 | 22 | 10 | 64 |
Total number of gains: 140; Total number of losses: 47; Total Number of normals: 301.
Somatic mutations of CAPNS1:
Generating mutation plots.
Highly correlated genes for CAPNS1:
Showing top 20/1388 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPNS1 | MFSD5 | 0.763472 | 11 | 0 | 11 |
| CAPNS1 | NAGK | 0.760611 | 11 | 0 | 11 |
| CAPNS1 | ANXA11 | 0.742929 | 11 | 0 | 11 |
| CAPNS1 | PITX1 | 0.742529 | 10 | 0 | 10 |
| CAPNS1 | PCBP3 | 0.735618 | 3 | 0 | 3 |
| CAPNS1 | PLEKHM1 | 0.735514 | 11 | 0 | 11 |
| CAPNS1 | TSPO | 0.733573 | 11 | 0 | 11 |
| CAPNS1 | SNORA68 | 0.733079 | 4 | 0 | 4 |
| CAPNS1 | EVPL | 0.732397 | 11 | 0 | 11 |
| CAPNS1 | SH3GL1 | 0.729173 | 11 | 0 | 11 |
| CAPNS1 | TSG101 | 0.726561 | 10 | 0 | 10 |
| CAPNS1 | MALL | 0.725508 | 10 | 0 | 10 |
| CAPNS1 | MAPK3 | 0.723051 | 10 | 0 | 10 |
| CAPNS1 | DOCK9 | 0.71894 | 11 | 0 | 11 |
| CAPNS1 | RNF135 | 0.718184 | 6 | 0 | 6 |
| CAPNS1 | MGST2 | 0.715546 | 11 | 0 | 11 |
| CAPNS1 | SH3GLB2 | 0.715402 | 8 | 0 | 8 |
| CAPNS1 | TOM1 | 0.715111 | 11 | 0 | 11 |
| CAPNS1 | SCAMP2 | 0.713216 | 11 | 0 | 10 |
| CAPNS1 | GRN | 0.709705 | 10 | 0 | 10 |
For details and further investigation, click here
