| Full name: family with sequence similarity 200 member B | Alias Symbol: C4orf53 | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 285550 | HGNC ID: HGNC:27740 | Ensembl Gene: ENSG00000237765 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FAM200B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM200B | 285550 | 227466_at | -0.1925 | 0.7178 | |
| GSE26886 | FAM200B | 285550 | 227466_at | 0.5361 | 0.0171 | |
| GSE45670 | FAM200B | 285550 | 227466_at | -0.4668 | 0.0018 | |
| GSE53622 | FAM200B | 285550 | 64766 | -0.3348 | 0.0252 | |
| GSE53624 | FAM200B | 285550 | 64766 | -0.0120 | 0.9342 | |
| GSE63941 | FAM200B | 285550 | 227466_at | -0.3652 | 0.5323 | |
| GSE77861 | FAM200B | 285550 | 227466_at | -0.4794 | 0.3408 | |
| GSE97050 | FAM200B | A_19_P00322856 | -0.3547 | 0.2956 | ||
| SRP007169 | FAM200B | 285550 | RNAseq | 0.1916 | 0.7125 | |
| SRP008496 | FAM200B | 285550 | RNAseq | 0.4883 | 0.0974 | |
| SRP064894 | FAM200B | 285550 | RNAseq | 0.0979 | 0.5361 | |
| SRP133303 | FAM200B | 285550 | RNAseq | 0.0041 | 0.9804 | |
| SRP159526 | FAM200B | 285550 | RNAseq | 0.2449 | 0.2508 | |
| SRP193095 | FAM200B | 285550 | RNAseq | -0.3079 | 0.0058 | |
| SRP219564 | FAM200B | 285550 | RNAseq | -0.5795 | 0.0842 | |
| TCGA | FAM200B | 285550 | RNAseq | -0.0450 | 0.4768 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM200B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM200B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM200B | 285550 | 0 | 18 | 12 | |
| GSE20123 | FAM200B | 285550 | 0 | 18 | 12 | |
| GSE43470 | FAM200B | 285550 | 1 | 15 | 27 | |
| GSE46452 | FAM200B | 285550 | 1 | 36 | 22 | |
| GSE47630 | FAM200B | 285550 | 1 | 19 | 20 | |
| GSE54993 | FAM200B | 285550 | 10 | 0 | 60 | |
| GSE54994 | FAM200B | 285550 | 4 | 12 | 37 | |
| GSE60625 | FAM200B | 285550 | 0 | 0 | 11 | |
| GSE74703 | FAM200B | 285550 | 1 | 13 | 22 | |
| GSE74704 | FAM200B | 285550 | 0 | 11 | 9 | |
| TCGA | FAM200B | 285550 | 9 | 48 | 39 |
Total number of gains: 27; Total number of losses: 190; Total Number of normals: 271.
Somatic mutations of FAM200B:
Generating mutation plots.
Highly correlated genes for FAM200B:
Showing top 20/290 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM200B | DENND1A | 0.793224 | 3 | 0 | 3 |
| FAM200B | NDRG3 | 0.786111 | 3 | 0 | 3 |
| FAM200B | SETMAR | 0.754744 | 3 | 0 | 3 |
| FAM200B | RCOR3 | 0.745138 | 3 | 0 | 3 |
| FAM200B | CNST | 0.742792 | 3 | 0 | 3 |
| FAM200B | UHRF1BP1L | 0.731123 | 3 | 0 | 3 |
| FAM200B | BHLHB9 | 0.721069 | 3 | 0 | 3 |
| FAM200B | UBL7 | 0.719898 | 3 | 0 | 3 |
| FAM200B | MYL6B | 0.712821 | 4 | 0 | 3 |
| FAM200B | ASS1 | 0.710264 | 3 | 0 | 3 |
| FAM200B | PBX1 | 0.709386 | 4 | 0 | 3 |
| FAM200B | THRB | 0.705654 | 3 | 0 | 3 |
| FAM200B | PLXNB1 | 0.696295 | 3 | 0 | 3 |
| FAM200B | FRY | 0.695914 | 3 | 0 | 3 |
| FAM200B | TSNARE1 | 0.69547 | 3 | 0 | 3 |
| FAM200B | NXF1 | 0.695204 | 3 | 0 | 3 |
| FAM200B | ZSCAN21 | 0.694702 | 3 | 0 | 3 |
| FAM200B | SUGP2 | 0.692305 | 3 | 0 | 3 |
| FAM200B | ADHFE1 | 0.692238 | 3 | 0 | 3 |
| FAM200B | EPM2AIP1 | 0.690999 | 3 | 0 | 3 |
For details and further investigation, click here
