| Full name: consortin, connexin sorting protein | Alias Symbol: FLJ32001|PPP1R64 | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 163882 | HGNC ID: HGNC:26486 | Ensembl Gene: ENSG00000162852 | OMIM ID: 613439 |
| Drug and gene relationship at DGIdb | |||
Expression of CNST:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNST | 163882 | 225551_at | -0.3438 | 0.5818 | |
| GSE26886 | CNST | 163882 | 225551_at | -2.0860 | 0.0001 | |
| GSE45670 | CNST | 163882 | 225550_at | -0.6196 | 0.0008 | |
| GSE53622 | CNST | 163882 | 58921 | -0.5352 | 0.0000 | |
| GSE53624 | CNST | 163882 | 58921 | -0.7373 | 0.0000 | |
| GSE63941 | CNST | 163882 | 225550_at | -0.6981 | 0.0541 | |
| GSE77861 | CNST | 163882 | 225550_at | -0.3826 | 0.2296 | |
| GSE97050 | CNST | 163882 | A_33_P3376379 | -0.3543 | 0.1818 | |
| SRP007169 | CNST | 163882 | RNAseq | -1.6025 | 0.0008 | |
| SRP008496 | CNST | 163882 | RNAseq | -1.4848 | 0.0000 | |
| SRP064894 | CNST | 163882 | RNAseq | -1.3569 | 0.0000 | |
| SRP133303 | CNST | 163882 | RNAseq | -0.6418 | 0.0000 | |
| SRP159526 | CNST | 163882 | RNAseq | -0.0693 | 0.8547 | |
| SRP193095 | CNST | 163882 | RNAseq | -1.0980 | 0.0000 | |
| SRP219564 | CNST | 163882 | RNAseq | -0.6566 | 0.1371 | |
| TCGA | CNST | 163882 | RNAseq | -0.2289 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CNST expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNST:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNST | 163882 | 7 | 1 | 22 | |
| GSE20123 | CNST | 163882 | 7 | 1 | 22 | |
| GSE43470 | CNST | 163882 | 5 | 3 | 35 | |
| GSE46452 | CNST | 163882 | 4 | 2 | 53 | |
| GSE47630 | CNST | 163882 | 15 | 1 | 24 | |
| GSE54993 | CNST | 163882 | 0 | 6 | 64 | |
| GSE54994 | CNST | 163882 | 17 | 2 | 34 | |
| GSE60625 | CNST | 163882 | 0 | 0 | 11 | |
| GSE74703 | CNST | 163882 | 5 | 1 | 30 | |
| GSE74704 | CNST | 163882 | 2 | 0 | 18 | |
| TCGA | CNST | 163882 | 46 | 5 | 45 |
Total number of gains: 108; Total number of losses: 22; Total Number of normals: 358.
Somatic mutations of CNST:
Generating mutation plots.
Highly correlated genes for CNST:
Showing top 20/739 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNST | ZDHHC17 | 0.832474 | 3 | 0 | 3 |
| CNST | EPG5 | 0.81148 | 4 | 0 | 4 |
| CNST | GBA2 | 0.800415 | 3 | 0 | 3 |
| CNST | EPC1 | 0.79651 | 3 | 0 | 3 |
| CNST | TRIM23 | 0.792372 | 3 | 0 | 3 |
| CNST | BTD | 0.769755 | 3 | 0 | 3 |
| CNST | ALDH6A1 | 0.760343 | 3 | 0 | 3 |
| CNST | ATRX | 0.760204 | 3 | 0 | 3 |
| CNST | TP53BP2 | 0.759005 | 4 | 0 | 4 |
| CNST | RGMB | 0.750299 | 3 | 0 | 3 |
| CNST | IGIP | 0.747639 | 3 | 0 | 3 |
| CNST | KLF2 | 0.746757 | 4 | 0 | 4 |
| CNST | NDUFA13 | 0.74405 | 3 | 0 | 3 |
| CNST | AFF3 | 0.742843 | 3 | 0 | 3 |
| CNST | FAM200B | 0.742792 | 3 | 0 | 3 |
| CNST | LSM14A | 0.742023 | 3 | 0 | 3 |
| CNST | APOB | 0.740754 | 3 | 0 | 3 |
| CNST | CDC42BPA | 0.739729 | 3 | 0 | 3 |
| CNST | DNALI1 | 0.736277 | 3 | 0 | 3 |
| CNST | MCFD2 | 0.734796 | 3 | 0 | 3 |
For details and further investigation, click here
