Full name: argininosuccinate synthase 1 | Alias Symbol: CTLN1 | ||
Type: protein-coding gene | Cytoband: 9q34.11 | ||
Entrez ID: 445 | HGNC ID: HGNC:758 | Ensembl Gene: ENSG00000130707 | OMIM ID: 603470 |
Drug and gene relationship at DGIdb |
Expression of ASS1:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE17351 | ASS1 | 445 | 207076_s_at | 0.8809 | 0.3886 | |
GSE20347 | ASS1 | 445 | 207076_s_at | 0.4816 | 0.2326 | |
GSE23400 | ASS1 | 445 | 207076_s_at | 0.3065 | 0.0902 | |
GSE26886 | ASS1 | 445 | 207076_s_at | 0.2927 | 0.5450 | |
GSE29001 | ASS1 | 445 | 207076_s_at | 0.1995 | 0.7205 | |
GSE38129 | ASS1 | 445 | 207076_s_at | 0.1110 | 0.7362 | |
GSE45670 | ASS1 | 445 | 207076_s_at | 0.8588 | 0.0158 | |
GSE53622 | ASS1 | 445 | 13284 | 0.4046 | 0.0053 | |
GSE53624 | ASS1 | 445 | 13284 | 0.5058 | 0.0000 | |
GSE63941 | ASS1 | 445 | 207076_s_at | 1.9802 | 0.2261 | |
GSE77861 | ASS1 | 445 | 207076_s_at | -0.1100 | 0.9151 | |
GSE97050 | ASS1 | 445 | A_23_P31921 | -0.0625 | 0.8315 | |
SRP007169 | ASS1 | 445 | RNAseq | -0.2337 | 0.7797 | |
SRP008496 | ASS1 | 445 | RNAseq | 0.1111 | 0.8797 | |
SRP064894 | ASS1 | 445 | RNAseq | 0.5272 | 0.1345 | |
SRP133303 | ASS1 | 445 | RNAseq | 0.8591 | 0.0018 | |
SRP159526 | ASS1 | 445 | RNAseq | 0.2796 | 0.6406 | |
SRP193095 | ASS1 | 445 | RNAseq | 0.6659 | 0.0039 | |
SRP219564 | ASS1 | 445 | RNAseq | 0.6128 | 0.2757 | |
TCGA | ASS1 | 445 | RNAseq | 0.0094 | 0.9478 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASS1 expression:
Note: Click image to view full size file.
Copy number change of ASS1:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | ASS1 | 445 | 6 | 9 | 15 | |
GSE20123 | ASS1 | 445 | 6 | 9 | 15 | |
GSE43470 | ASS1 | 445 | 5 | 7 | 31 | |
GSE46452 | ASS1 | 445 | 6 | 13 | 40 | |
GSE47630 | ASS1 | 445 | 3 | 16 | 21 | |
GSE54993 | ASS1 | 445 | 3 | 3 | 64 | |
GSE54994 | ASS1 | 445 | 12 | 9 | 32 | |
GSE60625 | ASS1 | 445 | 0 | 0 | 11 | |
GSE74703 | ASS1 | 445 | 5 | 5 | 26 | |
GSE74704 | ASS1 | 445 | 3 | 7 | 10 | |
TCGA | ASS1 | 445 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.
Somatic mutations of ASS1:
Generating mutation plots.
Highly correlated genes for ASS1:
Showing top 20/82 corelated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
ASS1 | SDCBP | 0.800735 | 3 | 0 | 3 |
ASS1 | RAB2B | 0.763387 | 3 | 0 | 3 |
ASS1 | BCORL1 | 0.727945 | 3 | 0 | 3 |
ASS1 | CHD8 | 0.72676 | 3 | 0 | 3 |
ASS1 | PHPT1 | 0.717795 | 3 | 0 | 3 |
ASS1 | FAM200B | 0.710264 | 3 | 0 | 3 |
ASS1 | CPLX1 | 0.688713 | 3 | 0 | 3 |
ASS1 | GPX1 | 0.687025 | 3 | 0 | 3 |
ASS1 | PPP1R16A | 0.683592 | 3 | 0 | 3 |
ASS1 | ARL6IP6 | 0.67948 | 3 | 0 | 3 |
ASS1 | HMGN3 | 0.672561 | 4 | 0 | 3 |
ASS1 | SLC6A8 | 0.668429 | 3 | 0 | 3 |
ASS1 | DHRSX | 0.665831 | 3 | 0 | 3 |
ASS1 | TCEA1 | 0.661038 | 4 | 0 | 3 |
ASS1 | PRELID2 | 0.645647 | 4 | 0 | 3 |
ASS1 | MANEA | 0.642989 | 3 | 0 | 3 |
ASS1 | SS18L1 | 0.641333 | 4 | 0 | 3 |
ASS1 | IRF9 | 0.638433 | 4 | 0 | 3 |
ASS1 | GALNT2 | 0.6384 | 3 | 0 | 3 |
ASS1 | DGCR2 | 0.638262 | 3 | 0 | 3 |
For details and further investigation, click here