| Full name: cysteine and glycine rich protein 1 | Alias Symbol: CSRP|D1S181E | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 1465 | HGNC ID: HGNC:2469 | Ensembl Gene: ENSG00000159176 | OMIM ID: 123876 |
| Drug and gene relationship at DGIdb | |||
Expression of CSRP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSRP1 | 1465 | 200621_at | -1.3433 | 0.1513 | |
| GSE20347 | CSRP1 | 1465 | 200621_at | -0.4122 | 0.0654 | |
| GSE23400 | CSRP1 | 1465 | 200621_at | -0.8325 | 0.0000 | |
| GSE26886 | CSRP1 | 1465 | 200621_at | -0.0756 | 0.7796 | |
| GSE29001 | CSRP1 | 1465 | 200621_at | -0.4118 | 0.2033 | |
| GSE38129 | CSRP1 | 1465 | 200621_at | -0.8158 | 0.0161 | |
| GSE45670 | CSRP1 | 1465 | 200621_at | -1.3597 | 0.0000 | |
| GSE53622 | CSRP1 | 1465 | 22920 | -1.3843 | 0.0000 | |
| GSE53624 | CSRP1 | 1465 | 22920 | -1.1584 | 0.0000 | |
| GSE63941 | CSRP1 | 1465 | 200621_at | -0.5413 | 0.5116 | |
| GSE77861 | CSRP1 | 1465 | 200621_at | 0.3500 | 0.1215 | |
| GSE97050 | CSRP1 | 1465 | A_23_P74359 | -1.7012 | 0.0897 | |
| SRP007169 | CSRP1 | 1465 | RNAseq | 0.3074 | 0.4718 | |
| SRP008496 | CSRP1 | 1465 | RNAseq | 1.0250 | 0.0011 | |
| SRP064894 | CSRP1 | 1465 | RNAseq | -0.5262 | 0.2001 | |
| SRP133303 | CSRP1 | 1465 | RNAseq | -0.6213 | 0.2101 | |
| SRP159526 | CSRP1 | 1465 | RNAseq | -1.1302 | 0.0165 | |
| SRP193095 | CSRP1 | 1465 | RNAseq | -0.2900 | 0.0739 | |
| SRP219564 | CSRP1 | 1465 | RNAseq | -1.2783 | 0.1726 | |
| TCGA | CSRP1 | 1465 | RNAseq | -0.2827 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by CSRP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSRP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSRP1 | 1465 | 11 | 0 | 19 | |
| GSE20123 | CSRP1 | 1465 | 11 | 0 | 19 | |
| GSE43470 | CSRP1 | 1465 | 6 | 0 | 37 | |
| GSE46452 | CSRP1 | 1465 | 3 | 1 | 55 | |
| GSE47630 | CSRP1 | 1465 | 14 | 0 | 26 | |
| GSE54993 | CSRP1 | 1465 | 0 | 6 | 64 | |
| GSE54994 | CSRP1 | 1465 | 15 | 0 | 38 | |
| GSE60625 | CSRP1 | 1465 | 0 | 0 | 11 | |
| GSE74703 | CSRP1 | 1465 | 6 | 0 | 30 | |
| GSE74704 | CSRP1 | 1465 | 5 | 0 | 15 | |
| TCGA | CSRP1 | 1465 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of CSRP1:
Generating mutation plots.
Highly correlated genes for CSRP1:
Showing top 20/787 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSRP1 | ACTBL2 | 0.848645 | 3 | 0 | 3 |
| CSRP1 | ASB5 | 0.810599 | 5 | 0 | 5 |
| CSRP1 | MYOCD | 0.793598 | 6 | 0 | 6 |
| CSRP1 | ARHGAP6 | 0.78258 | 9 | 0 | 9 |
| CSRP1 | ANGPTL1 | 0.776734 | 6 | 0 | 6 |
| CSRP1 | BHMT2 | 0.769949 | 9 | 0 | 9 |
| CSRP1 | LINC01082 | 0.769062 | 4 | 0 | 4 |
| CSRP1 | AOC3 | 0.768587 | 12 | 0 | 11 |
| CSRP1 | MYL5 | 0.767241 | 4 | 0 | 3 |
| CSRP1 | LMOD1 | 0.766201 | 12 | 0 | 11 |
| CSRP1 | SYNPO2 | 0.765678 | 7 | 0 | 7 |
| CSRP1 | PYGM | 0.763004 | 9 | 0 | 8 |
| CSRP1 | PDE5A | 0.760396 | 9 | 0 | 8 |
| CSRP1 | SCN7A | 0.760343 | 8 | 0 | 8 |
| CSRP1 | PPP1R12A | 0.76028 | 8 | 0 | 8 |
| CSRP1 | MYOC | 0.759863 | 8 | 0 | 8 |
| CSRP1 | KCNMB1 | 0.759763 | 12 | 0 | 12 |
| CSRP1 | LIMS2 | 0.75919 | 9 | 0 | 8 |
| CSRP1 | MAMDC2 | 0.756095 | 6 | 0 | 6 |
| CSRP1 | CHRDL1 | 0.752511 | 10 | 0 | 9 |
For details and further investigation, click here
