| Full name: FERM, ARH/RhoGEF and pleckstrin domain protein 1 | Alias Symbol: CDEP|PLEKHC2|MGC87400|PPP1R75 | ||
| Type: protein-coding gene | Cytoband: 13q32.2 | ||
| Entrez ID: 10160 | HGNC ID: HGNC:3591 | Ensembl Gene: ENSG00000152767 | OMIM ID: 602654 |
| Drug and gene relationship at DGIdb | |||
Expression of FARP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FARP1 | 10160 | 201910_at | 0.5833 | 0.2437 | |
| GSE20347 | FARP1 | 10160 | 201910_at | 0.9047 | 0.0001 | |
| GSE23400 | FARP1 | 10160 | 201910_at | 0.3881 | 0.0003 | |
| GSE26886 | FARP1 | 10160 | 201910_at | 1.6318 | 0.0001 | |
| GSE29001 | FARP1 | 10160 | 201910_at | 1.0218 | 0.0492 | |
| GSE38129 | FARP1 | 10160 | 201910_at | 0.6476 | 0.0135 | |
| GSE45670 | FARP1 | 10160 | 201910_at | 0.3400 | 0.2433 | |
| GSE53622 | FARP1 | 10160 | 40705 | 1.3674 | 0.0000 | |
| GSE53624 | FARP1 | 10160 | 40705 | 1.7809 | 0.0000 | |
| GSE63941 | FARP1 | 10160 | 201911_s_at | -1.6839 | 0.1067 | |
| GSE77861 | FARP1 | 10160 | 201910_at | 0.6561 | 0.0099 | |
| GSE97050 | FARP1 | 10160 | A_23_P204998 | 0.0314 | 0.9445 | |
| SRP007169 | FARP1 | 10160 | RNAseq | 2.8315 | 0.0001 | |
| SRP008496 | FARP1 | 10160 | RNAseq | 2.8938 | 0.0000 | |
| SRP064894 | FARP1 | 10160 | RNAseq | 0.7694 | 0.0000 | |
| SRP133303 | FARP1 | 10160 | RNAseq | 0.9405 | 0.0001 | |
| SRP159526 | FARP1 | 10160 | RNAseq | 1.9292 | 0.0000 | |
| SRP193095 | FARP1 | 10160 | RNAseq | 0.7188 | 0.0003 | |
| SRP219564 | FARP1 | 10160 | RNAseq | 0.7423 | 0.1729 | |
| TCGA | FARP1 | 10160 | RNAseq | -0.1175 | 0.2478 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by FARP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FARP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FARP1 | 10160 | 4 | 9 | 17 | |
| GSE20123 | FARP1 | 10160 | 4 | 9 | 17 | |
| GSE43470 | FARP1 | 10160 | 4 | 12 | 27 | |
| GSE46452 | FARP1 | 10160 | 0 | 32 | 27 | |
| GSE47630 | FARP1 | 10160 | 3 | 26 | 11 | |
| GSE54993 | FARP1 | 10160 | 11 | 4 | 55 | |
| GSE54994 | FARP1 | 10160 | 3 | 12 | 38 | |
| GSE60625 | FARP1 | 10160 | 0 | 3 | 8 | |
| GSE74703 | FARP1 | 10160 | 3 | 10 | 23 | |
| GSE74704 | FARP1 | 10160 | 2 | 8 | 10 | |
| TCGA | FARP1 | 10160 | 13 | 34 | 49 |
Total number of gains: 47; Total number of losses: 159; Total Number of normals: 282.
Somatic mutations of FARP1:
Generating mutation plots.
Highly correlated genes for FARP1:
Showing top 20/1663 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FARP1 | FADS1 | 0.803972 | 3 | 0 | 3 |
| FARP1 | RAB34 | 0.797238 | 3 | 0 | 3 |
| FARP1 | ZBED1 | 0.78467 | 5 | 0 | 5 |
| FARP1 | CCDC127 | 0.778204 | 3 | 0 | 3 |
| FARP1 | DHRSX | 0.760507 | 4 | 0 | 4 |
| FARP1 | WDR81 | 0.754577 | 5 | 0 | 5 |
| FARP1 | GXYLT2 | 0.74886 | 5 | 0 | 5 |
| FARP1 | SLC35B2 | 0.734636 | 3 | 0 | 3 |
| FARP1 | PYCR2 | 0.731816 | 3 | 0 | 3 |
| FARP1 | ZNF275 | 0.727898 | 7 | 0 | 6 |
| FARP1 | SFT2D3 | 0.726877 | 3 | 0 | 3 |
| FARP1 | GLIS2 | 0.725343 | 5 | 0 | 5 |
| FARP1 | MEIS2 | 0.724963 | 3 | 0 | 3 |
| FARP1 | NF1 | 0.719215 | 3 | 0 | 3 |
| FARP1 | LBH | 0.712459 | 12 | 0 | 12 |
| FARP1 | TP53I13 | 0.711568 | 7 | 0 | 6 |
| FARP1 | PATZ1 | 0.711178 | 8 | 0 | 7 |
| FARP1 | SLC39A13 | 0.707519 | 7 | 0 | 6 |
| FARP1 | TRAM2 | 0.70506 | 11 | 0 | 11 |
| FARP1 | SSBP4 | 0.704374 | 6 | 0 | 5 |
For details and further investigation, click here
