| Full name: GLIS family zinc finger 2 | Alias Symbol: NPHP7 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 84662 | HGNC ID: HGNC:29450 | Ensembl Gene: ENSG00000126603 | OMIM ID: 608539 |
| Drug and gene relationship at DGIdb | |||
Expression of GLIS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLIS2 | 84662 | 223378_at | 0.5520 | 0.4388 | |
| GSE26886 | GLIS2 | 84662 | 223378_at | 2.1829 | 0.0000 | |
| GSE45670 | GLIS2 | 84662 | 223378_at | -0.3142 | 0.4385 | |
| GSE53622 | GLIS2 | 84662 | 143998 | 0.7472 | 0.0000 | |
| GSE53624 | GLIS2 | 84662 | 143998 | 1.0494 | 0.0000 | |
| GSE63941 | GLIS2 | 84662 | 223378_at | -1.1248 | 0.0427 | |
| GSE77861 | GLIS2 | 84662 | 223378_at | 0.2629 | 0.0779 | |
| GSE97050 | GLIS2 | 84662 | A_33_P3333224 | 0.3932 | 0.2928 | |
| SRP007169 | GLIS2 | 84662 | RNAseq | 3.3865 | 0.0001 | |
| SRP008496 | GLIS2 | 84662 | RNAseq | 3.9298 | 0.0000 | |
| SRP064894 | GLIS2 | 84662 | RNAseq | 1.0598 | 0.0008 | |
| SRP133303 | GLIS2 | 84662 | RNAseq | 1.3506 | 0.0000 | |
| SRP159526 | GLIS2 | 84662 | RNAseq | 1.0534 | 0.0000 | |
| SRP193095 | GLIS2 | 84662 | RNAseq | 1.7486 | 0.0000 | |
| SRP219564 | GLIS2 | 84662 | RNAseq | 0.6366 | 0.3583 | |
| TCGA | GLIS2 | 84662 | RNAseq | -0.0502 | 0.6277 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by GLIS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLIS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLIS2 | 84662 | 5 | 5 | 20 | |
| GSE20123 | GLIS2 | 84662 | 5 | 4 | 21 | |
| GSE43470 | GLIS2 | 84662 | 5 | 6 | 32 | |
| GSE46452 | GLIS2 | 84662 | 38 | 1 | 20 | |
| GSE47630 | GLIS2 | 84662 | 13 | 6 | 21 | |
| GSE54993 | GLIS2 | 84662 | 3 | 5 | 62 | |
| GSE54994 | GLIS2 | 84662 | 5 | 9 | 39 | |
| GSE60625 | GLIS2 | 84662 | 4 | 0 | 7 | |
| GSE74703 | GLIS2 | 84662 | 5 | 4 | 27 | |
| GSE74704 | GLIS2 | 84662 | 3 | 2 | 15 | |
| TCGA | GLIS2 | 84662 | 19 | 13 | 64 |
Total number of gains: 105; Total number of losses: 55; Total Number of normals: 328.
Somatic mutations of GLIS2:
Generating mutation plots.
Highly correlated genes for GLIS2:
Showing top 20/1221 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLIS2 | SLC38A10 | 0.824058 | 3 | 0 | 3 |
| GLIS2 | KHSRP | 0.813583 | 3 | 0 | 3 |
| GLIS2 | RAB34 | 0.793072 | 3 | 0 | 3 |
| GLIS2 | TRIM47 | 0.788772 | 3 | 0 | 3 |
| GLIS2 | SLC39A13 | 0.781492 | 7 | 0 | 7 |
| GLIS2 | EIF5A2 | 0.772259 | 6 | 0 | 6 |
| GLIS2 | TMEM132A | 0.759663 | 3 | 0 | 3 |
| GLIS2 | MAK16 | 0.758882 | 3 | 0 | 3 |
| GLIS2 | MMD | 0.751287 | 8 | 0 | 8 |
| GLIS2 | CHST15 | 0.747293 | 7 | 0 | 6 |
| GLIS2 | MTCH1 | 0.739643 | 3 | 0 | 3 |
| GLIS2 | PDGFC | 0.739459 | 6 | 0 | 6 |
| GLIS2 | KRTCAP2 | 0.737324 | 3 | 0 | 3 |
| GLIS2 | CEBPB | 0.737321 | 6 | 0 | 6 |
| GLIS2 | EFEMP2 | 0.732975 | 8 | 0 | 7 |
| GLIS2 | ALDH1L2 | 0.730545 | 4 | 0 | 3 |
| GLIS2 | RAB31 | 0.730334 | 5 | 0 | 5 |
| GLIS2 | CDC42EP4 | 0.728998 | 4 | 0 | 4 |
| GLIS2 | IGFBP7 | 0.72859 | 7 | 0 | 7 |
| GLIS2 | SRRT | 0.728231 | 4 | 0 | 3 |
For details and further investigation, click here
