| Full name: LBH regulator of WNT signaling pathway | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p23.1 | ||
| Entrez ID: 81606 | HGNC ID: HGNC:29532 | Ensembl Gene: ENSG00000213626 | OMIM ID: 611763 |
| Drug and gene relationship at DGIdb | |||
Expression of LBH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LBH | 81606 | 221011_s_at | 0.5956 | 0.3274 | |
| GSE20347 | LBH | 81606 | 221011_s_at | 1.4824 | 0.0000 | |
| GSE23400 | LBH | 81606 | 221011_s_at | 0.7629 | 0.0000 | |
| GSE26886 | LBH | 81606 | 221011_s_at | 1.3495 | 0.0048 | |
| GSE29001 | LBH | 81606 | 221011_s_at | 1.6074 | 0.0003 | |
| GSE38129 | LBH | 81606 | 221011_s_at | 0.9843 | 0.0167 | |
| GSE45670 | LBH | 81606 | 221011_s_at | 0.1249 | 0.7506 | |
| GSE53622 | LBH | 81606 | 55904 | 0.7060 | 0.0000 | |
| GSE53624 | LBH | 81606 | 50081 | 1.0633 | 0.0000 | |
| GSE63941 | LBH | 81606 | 221011_s_at | -4.1664 | 0.0128 | |
| GSE77861 | LBH | 81606 | 221011_s_at | 1.9777 | 0.0003 | |
| GSE97050 | LBH | 81606 | A_33_P3364263 | 0.4838 | 0.4226 | |
| SRP007169 | LBH | 81606 | RNAseq | 3.1926 | 0.0000 | |
| SRP008496 | LBH | 81606 | RNAseq | 3.5293 | 0.0000 | |
| SRP064894 | LBH | 81606 | RNAseq | 0.9110 | 0.0007 | |
| SRP133303 | LBH | 81606 | RNAseq | 0.8364 | 0.0000 | |
| SRP159526 | LBH | 81606 | RNAseq | 0.9726 | 0.0003 | |
| SRP193095 | LBH | 81606 | RNAseq | 1.5022 | 0.0000 | |
| SRP219564 | LBH | 81606 | RNAseq | 0.2053 | 0.8007 | |
| TCGA | LBH | 81606 | RNAseq | 0.2339 | 0.0095 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by LBH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LBH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LBH | 81606 | 11 | 1 | 18 | |
| GSE20123 | LBH | 81606 | 9 | 1 | 20 | |
| GSE43470 | LBH | 81606 | 2 | 1 | 40 | |
| GSE46452 | LBH | 81606 | 2 | 4 | 53 | |
| GSE47630 | LBH | 81606 | 8 | 0 | 32 | |
| GSE54993 | LBH | 81606 | 0 | 6 | 64 | |
| GSE54994 | LBH | 81606 | 10 | 0 | 43 | |
| GSE60625 | LBH | 81606 | 0 | 3 | 8 | |
| GSE74703 | LBH | 81606 | 2 | 0 | 34 | |
| GSE74704 | LBH | 81606 | 9 | 1 | 10 | |
| TCGA | LBH | 81606 | 36 | 2 | 58 |
Total number of gains: 89; Total number of losses: 19; Total Number of normals: 380.
Somatic mutations of LBH:
Generating mutation plots.
Highly correlated genes for LBH:
Showing top 20/1426 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LBH | FSTL1 | 0.762361 | 13 | 0 | 13 |
| LBH | PXDN | 0.749486 | 12 | 0 | 12 |
| LBH | COL4A2 | 0.748218 | 12 | 0 | 11 |
| LBH | LGALS1 | 0.744068 | 11 | 0 | 11 |
| LBH | CALU | 0.743424 | 12 | 0 | 11 |
| LBH | CDK14 | 0.738808 | 10 | 0 | 10 |
| LBH | TMEM263 | 0.73625 | 7 | 0 | 7 |
| LBH | WDR81 | 0.735056 | 3 | 0 | 3 |
| LBH | TRAM2 | 0.73049 | 11 | 0 | 10 |
| LBH | FKBP7 | 0.725418 | 7 | 0 | 7 |
| LBH | VCAN | 0.723689 | 13 | 0 | 12 |
| LBH | LINC00888 | 0.720698 | 4 | 0 | 3 |
| LBH | FARP1 | 0.712459 | 12 | 0 | 12 |
| LBH | MMD | 0.712448 | 13 | 0 | 12 |
| LBH | ITGB1 | 0.71073 | 11 | 0 | 10 |
| LBH | IGFBP7 | 0.709637 | 12 | 0 | 10 |
| LBH | RAI14 | 0.704013 | 12 | 0 | 12 |
| LBH | XXYLT1 | 0.70315 | 3 | 0 | 3 |
| LBH | LAMC1 | 0.702911 | 13 | 0 | 11 |
| LBH | SPARC | 0.701896 | 13 | 0 | 12 |
For details and further investigation, click here
