| Full name: fibulin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 2199 | HGNC ID: HGNC:3601 | Ensembl Gene: ENSG00000163520 | OMIM ID: 135821 |
| Drug and gene relationship at DGIdb | |||
Expression of FBLN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBLN2 | 2199 | 203886_s_at | -0.2019 | 0.8150 | |
| GSE20347 | FBLN2 | 2199 | 203886_s_at | 0.5371 | 0.0194 | |
| GSE23400 | FBLN2 | 2199 | 203886_s_at | -0.1254 | 0.3097 | |
| GSE26886 | FBLN2 | 2199 | 203886_s_at | 2.0988 | 0.0000 | |
| GSE29001 | FBLN2 | 2199 | 203886_s_at | 0.7079 | 0.0541 | |
| GSE38129 | FBLN2 | 2199 | 203886_s_at | 0.0479 | 0.9181 | |
| GSE45670 | FBLN2 | 2199 | 203886_s_at | -1.2808 | 0.0046 | |
| GSE53622 | FBLN2 | 2199 | 111922 | -0.0849 | 0.4359 | |
| GSE53624 | FBLN2 | 2199 | 111922 | 0.0594 | 0.5332 | |
| GSE63941 | FBLN2 | 2199 | 203886_s_at | -4.0020 | 0.0003 | |
| GSE77861 | FBLN2 | 2199 | 203886_s_at | 0.2546 | 0.1601 | |
| GSE97050 | FBLN2 | 2199 | A_23_P143981 | -0.2009 | 0.6223 | |
| SRP007169 | FBLN2 | 2199 | RNAseq | 3.6156 | 0.0000 | |
| SRP008496 | FBLN2 | 2199 | RNAseq | 4.2974 | 0.0000 | |
| SRP064894 | FBLN2 | 2199 | RNAseq | -0.2769 | 0.4921 | |
| SRP133303 | FBLN2 | 2199 | RNAseq | 0.2294 | 0.5808 | |
| SRP159526 | FBLN2 | 2199 | RNAseq | -0.3106 | 0.4477 | |
| SRP193095 | FBLN2 | 2199 | RNAseq | 2.7771 | 0.0000 | |
| SRP219564 | FBLN2 | 2199 | RNAseq | 0.8799 | 0.2461 | |
| TCGA | FBLN2 | 2199 | RNAseq | -0.2795 | 0.0274 |
Upregulated datasets: 4; Downregulated datasets: 2.
Survival by FBLN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBLN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBLN2 | 2199 | 2 | 17 | 11 | |
| GSE20123 | FBLN2 | 2199 | 2 | 17 | 11 | |
| GSE43470 | FBLN2 | 2199 | 0 | 21 | 22 | |
| GSE46452 | FBLN2 | 2199 | 2 | 17 | 40 | |
| GSE47630 | FBLN2 | 2199 | 2 | 23 | 15 | |
| GSE54993 | FBLN2 | 2199 | 6 | 1 | 63 | |
| GSE54994 | FBLN2 | 2199 | 1 | 32 | 20 | |
| GSE60625 | FBLN2 | 2199 | 5 | 0 | 6 | |
| GSE74703 | FBLN2 | 2199 | 0 | 17 | 19 | |
| GSE74704 | FBLN2 | 2199 | 1 | 10 | 9 | |
| TCGA | FBLN2 | 2199 | 2 | 68 | 26 |
Total number of gains: 23; Total number of losses: 223; Total Number of normals: 242.
Somatic mutations of FBLN2:
Generating mutation plots.
Highly correlated genes for FBLN2:
Showing top 20/881 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBLN2 | ASB2 | 0.735672 | 4 | 0 | 4 |
| FBLN2 | FBN1 | 0.719207 | 11 | 0 | 10 |
| FBLN2 | CORO6 | 0.712621 | 3 | 0 | 3 |
| FBLN2 | PMP22 | 0.707873 | 12 | 0 | 11 |
| FBLN2 | OSR1 | 0.704326 | 4 | 0 | 4 |
| FBLN2 | LINC00888 | 0.703027 | 3 | 0 | 3 |
| FBLN2 | GPC3 | 0.700086 | 3 | 0 | 3 |
| FBLN2 | OLFML3 | 0.692011 | 13 | 0 | 11 |
| FBLN2 | NID2 | 0.692 | 9 | 0 | 8 |
| FBLN2 | ISLR | 0.688314 | 13 | 0 | 11 |
| FBLN2 | FSTL1 | 0.687004 | 13 | 0 | 13 |
| FBLN2 | LINC01279 | 0.686518 | 4 | 0 | 4 |
| FBLN2 | TIMP3 | 0.685647 | 11 | 0 | 10 |
| FBLN2 | COL5A1 | 0.68558 | 9 | 0 | 8 |
| FBLN2 | TSSC4 | 0.683398 | 3 | 0 | 3 |
| FBLN2 | EFEMP2 | 0.682688 | 13 | 0 | 12 |
| FBLN2 | OLFML1 | 0.681836 | 12 | 0 | 12 |
| FBLN2 | ARHGAP24 | 0.68183 | 4 | 0 | 4 |
| FBLN2 | LAMA4 | 0.680982 | 12 | 0 | 12 |
| FBLN2 | CTHRC1 | 0.678697 | 4 | 0 | 4 |
For details and further investigation, click here
