| Full name: tumor suppressing subtransferable candidate 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 10078 | HGNC ID: HGNC:12386 | Ensembl Gene: ENSG00000184281 | OMIM ID: 603852 |
| Drug and gene relationship at DGIdb | |||
Expression of TSSC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSSC4 | 10078 | 218612_s_at | -0.0622 | 0.8906 | |
| GSE20347 | TSSC4 | 10078 | 218612_s_at | -0.1362 | 0.1491 | |
| GSE23400 | TSSC4 | 10078 | 218612_s_at | -0.0098 | 0.8078 | |
| GSE26886 | TSSC4 | 10078 | 218612_s_at | 0.5700 | 0.0006 | |
| GSE29001 | TSSC4 | 10078 | 218612_s_at | 0.0241 | 0.9084 | |
| GSE38129 | TSSC4 | 10078 | 218612_s_at | -0.1633 | 0.1707 | |
| GSE45670 | TSSC4 | 10078 | 218612_s_at | 0.0876 | 0.4848 | |
| GSE53622 | TSSC4 | 10078 | 39416 | -0.1064 | 0.1296 | |
| GSE53624 | TSSC4 | 10078 | 39416 | -0.5287 | 0.0000 | |
| GSE63941 | TSSC4 | 10078 | 218612_s_at | -0.4291 | 0.2224 | |
| GSE77861 | TSSC4 | 10078 | 218612_s_at | 0.1010 | 0.6790 | |
| GSE97050 | TSSC4 | 10078 | A_33_P3325006 | -0.1897 | 0.3456 | |
| SRP007169 | TSSC4 | 10078 | RNAseq | -0.6893 | 0.0994 | |
| SRP008496 | TSSC4 | 10078 | RNAseq | -0.6095 | 0.0250 | |
| SRP064894 | TSSC4 | 10078 | RNAseq | -0.1467 | 0.6334 | |
| SRP133303 | TSSC4 | 10078 | RNAseq | -0.1692 | 0.2191 | |
| SRP159526 | TSSC4 | 10078 | RNAseq | -0.2147 | 0.3605 | |
| SRP193095 | TSSC4 | 10078 | RNAseq | -0.1287 | 0.2120 | |
| SRP219564 | TSSC4 | 10078 | RNAseq | 0.0027 | 0.9949 | |
| TCGA | TSSC4 | 10078 | RNAseq | -0.0280 | 0.6175 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TSSC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSSC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSSC4 | 10078 | 1 | 11 | 18 | |
| GSE20123 | TSSC4 | 10078 | 1 | 12 | 17 | |
| GSE43470 | TSSC4 | 10078 | 1 | 9 | 33 | |
| GSE46452 | TSSC4 | 10078 | 7 | 8 | 44 | |
| GSE47630 | TSSC4 | 10078 | 4 | 12 | 24 | |
| GSE54993 | TSSC4 | 10078 | 3 | 1 | 66 | |
| GSE54994 | TSSC4 | 10078 | 1 | 12 | 40 | |
| GSE60625 | TSSC4 | 10078 | 0 | 0 | 11 | |
| GSE74703 | TSSC4 | 10078 | 1 | 7 | 28 | |
| GSE74704 | TSSC4 | 10078 | 0 | 8 | 12 | |
| TCGA | TSSC4 | 10078 | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 119; Total Number of normals: 342.
Somatic mutations of TSSC4:
Generating mutation plots.
Highly correlated genes for TSSC4:
Showing top 20/79 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSSC4 | FAM181A | 0.696264 | 3 | 0 | 3 |
| TSSC4 | MAP7D1 | 0.694311 | 3 | 0 | 3 |
| TSSC4 | FBLN2 | 0.683398 | 3 | 0 | 3 |
| TSSC4 | BRD1 | 0.625114 | 3 | 0 | 3 |
| TSSC4 | SDC2 | 0.622359 | 3 | 0 | 3 |
| TSSC4 | TAF15 | 0.62196 | 4 | 0 | 3 |
| TSSC4 | NRK | 0.620948 | 4 | 0 | 3 |
| TSSC4 | KRTAP5-4 | 0.619328 | 3 | 0 | 3 |
| TSSC4 | NT5DC3 | 0.6123 | 3 | 0 | 3 |
| TSSC4 | GTF2F1 | 0.60545 | 5 | 0 | 3 |
| TSSC4 | NKX2-2 | 0.602306 | 3 | 0 | 3 |
| TSSC4 | TPBGL | 0.601682 | 3 | 0 | 3 |
| TSSC4 | RAI2 | 0.597711 | 4 | 0 | 3 |
| TSSC4 | C19orf47 | 0.596098 | 3 | 0 | 3 |
| TSSC4 | PPP1R9A | 0.595933 | 3 | 0 | 3 |
| TSSC4 | SHISA4 | 0.593574 | 6 | 0 | 6 |
| TSSC4 | C6orf226 | 0.590945 | 3 | 0 | 3 |
| TSSC4 | AGAP3 | 0.590812 | 3 | 0 | 3 |
| TSSC4 | GTPBP1 | 0.589087 | 4 | 0 | 3 |
| TSSC4 | NEUROG3 | 0.587309 | 4 | 0 | 3 |
For details and further investigation, click here
