| Full name: RAD51 paralog D | Alias Symbol: R51H3|Trad|HsTRAD | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 5892 | HGNC ID: HGNC:9823 | Ensembl Gene: ENSG00000185379 | OMIM ID: 602954 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RAD51D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAD51D | 5892 | 209965_s_at | 0.2242 | 0.5670 | |
| GSE20347 | RAD51D | 5892 | 209965_s_at | 0.3767 | 0.0059 | |
| GSE23400 | RAD51D | 5892 | 37793_r_at | 0.0159 | 0.7733 | |
| GSE26886 | RAD51D | 5892 | 209965_s_at | 0.4487 | 0.0153 | |
| GSE29001 | RAD51D | 5892 | 37793_r_at | 0.0066 | 0.9936 | |
| GSE38129 | RAD51D | 5892 | 209965_s_at | 0.5092 | 0.0000 | |
| GSE45670 | RAD51D | 5892 | 209965_s_at | 0.3704 | 0.0170 | |
| GSE53622 | RAD51D | 5892 | 79813 | 0.1645 | 0.1129 | |
| GSE53624 | RAD51D | 5892 | 79813 | -0.3252 | 0.0295 | |
| GSE63941 | RAD51D | 5892 | 209965_s_at | 0.0493 | 0.8860 | |
| GSE77861 | RAD51D | 5892 | 209965_s_at | 0.2044 | 0.2296 | |
| GSE97050 | RAD51D | 5892 | A_33_P3210827 | 0.1516 | 0.5159 | |
| SRP007169 | RAD51D | 5892 | RNAseq | 2.4450 | 0.0000 | |
| SRP008496 | RAD51D | 5892 | RNAseq | 2.5145 | 0.0000 | |
| SRP064894 | RAD51D | 5892 | RNAseq | 1.0444 | 0.0000 | |
| SRP133303 | RAD51D | 5892 | RNAseq | 0.3565 | 0.0025 | |
| SRP159526 | RAD51D | 5892 | RNAseq | 1.0201 | 0.0022 | |
| SRP193095 | RAD51D | 5892 | RNAseq | 0.5930 | 0.0000 | |
| SRP219564 | RAD51D | 5892 | RNAseq | 0.6039 | 0.0381 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by RAD51D expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of RAD51D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAD51D | 5892 | 5 | 1 | 24 | |
| GSE20123 | RAD51D | 5892 | 5 | 1 | 24 | |
| GSE43470 | RAD51D | 5892 | 1 | 2 | 40 | |
| GSE46452 | RAD51D | 5892 | 34 | 0 | 25 | |
| GSE47630 | RAD51D | 5892 | 7 | 1 | 32 | |
| GSE54993 | RAD51D | 5892 | 3 | 3 | 64 | |
| GSE54994 | RAD51D | 5892 | 8 | 6 | 39 | |
| GSE60625 | RAD51D | 5892 | 4 | 0 | 7 | |
| GSE74703 | RAD51D | 5892 | 1 | 1 | 34 | |
| GSE74704 | RAD51D | 5892 | 3 | 1 | 16 | |
| TCGA | RAD51D | 5892 | 20 | 9 | 67 |
Total number of gains: 91; Total number of losses: 25; Total Number of normals: 372.
Somatic mutations of RAD51D:
Generating mutation plots.
Highly correlated genes for RAD51D:
Showing top 20/316 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAD51D | TRIM31 | 0.819832 | 3 | 0 | 3 |
| RAD51D | HPS1 | 0.769593 | 3 | 0 | 3 |
| RAD51D | FURIN | 0.738598 | 3 | 0 | 3 |
| RAD51D | DCAF12L2 | 0.737333 | 3 | 0 | 3 |
| RAD51D | C20orf144 | 0.732003 | 3 | 0 | 3 |
| RAD51D | GRK6 | 0.721218 | 3 | 0 | 3 |
| RAD51D | TOX2 | 0.718942 | 3 | 0 | 3 |
| RAD51D | PPP2R5D | 0.713494 | 4 | 0 | 3 |
| RAD51D | RUNDC3A | 0.710336 | 3 | 0 | 3 |
| RAD51D | ZNF526 | 0.709206 | 3 | 0 | 3 |
| RAD51D | GYPE | 0.7091 | 3 | 0 | 3 |
| RAD51D | WNT9A | 0.706464 | 3 | 0 | 3 |
| RAD51D | ARVCF | 0.705398 | 4 | 0 | 3 |
| RAD51D | DCAF15 | 0.702313 | 3 | 0 | 3 |
| RAD51D | FBXL15 | 0.696109 | 3 | 0 | 3 |
| RAD51D | TRAPPC9 | 0.690718 | 4 | 0 | 3 |
| RAD51D | TSPAN10 | 0.688841 | 3 | 0 | 3 |
| RAD51D | PKDCC | 0.686761 | 4 | 0 | 4 |
| RAD51D | RUFY4 | 0.681574 | 3 | 0 | 3 |
| RAD51D | ALKBH5 | 0.679191 | 4 | 0 | 3 |
For details and further investigation, click here
