| Full name: protein phosphatase 2 regulatory subunit Bbeta | Alias Symbol: PR55-BETA|PR52B|B55beta | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 5521 | HGNC ID: HGNC:9305 | Ensembl Gene: ENSG00000156475 | OMIM ID: 604325 |
| Drug and gene relationship at DGIdb | |||
PPP2R2B involved pathways:
Expression of PPP2R2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP2R2B | 5521 | 213849_s_at | -0.2963 | 0.7054 | |
| GSE20347 | PPP2R2B | 5521 | 205643_s_at | -0.0800 | 0.3328 | |
| GSE23400 | PPP2R2B | 5521 | 205643_s_at | -0.1652 | 0.0015 | |
| GSE26886 | PPP2R2B | 5521 | 213849_s_at | 0.2743 | 0.6961 | |
| GSE29001 | PPP2R2B | 5521 | 213849_s_at | -0.1640 | 0.7190 | |
| GSE38129 | PPP2R2B | 5521 | 205643_s_at | -0.1984 | 0.0065 | |
| GSE45670 | PPP2R2B | 5521 | 213849_s_at | -0.3255 | 0.4257 | |
| GSE53622 | PPP2R2B | 5521 | 11513 | -0.4098 | 0.0129 | |
| GSE53624 | PPP2R2B | 5521 | 11513 | -0.4859 | 0.0003 | |
| GSE63941 | PPP2R2B | 5521 | 213849_s_at | 0.4048 | 0.7342 | |
| GSE77861 | PPP2R2B | 5521 | 205643_s_at | -0.0845 | 0.3747 | |
| GSE97050 | PPP2R2B | 5521 | A_23_P213620 | -0.1860 | 0.5720 | |
| SRP064894 | PPP2R2B | 5521 | RNAseq | -0.3464 | 0.3920 | |
| SRP133303 | PPP2R2B | 5521 | RNAseq | 0.2548 | 0.2949 | |
| SRP159526 | PPP2R2B | 5521 | RNAseq | 1.7433 | 0.0493 | |
| SRP193095 | PPP2R2B | 5521 | RNAseq | 0.7059 | 0.0005 | |
| SRP219564 | PPP2R2B | 5521 | RNAseq | 0.0485 | 0.9434 | |
| TCGA | PPP2R2B | 5521 | RNAseq | -0.1994 | 0.6277 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PPP2R2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP2R2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP2R2B | 5521 | 1 | 12 | 17 | |
| GSE20123 | PPP2R2B | 5521 | 1 | 12 | 17 | |
| GSE43470 | PPP2R2B | 5521 | 2 | 9 | 32 | |
| GSE46452 | PPP2R2B | 5521 | 0 | 27 | 32 | |
| GSE47630 | PPP2R2B | 5521 | 0 | 20 | 20 | |
| GSE54993 | PPP2R2B | 5521 | 9 | 1 | 60 | |
| GSE54994 | PPP2R2B | 5521 | 2 | 15 | 36 | |
| GSE60625 | PPP2R2B | 5521 | 0 | 0 | 11 | |
| GSE74703 | PPP2R2B | 5521 | 2 | 7 | 27 | |
| GSE74704 | PPP2R2B | 5521 | 1 | 7 | 12 | |
| TCGA | PPP2R2B | 5521 | 3 | 40 | 53 |
Total number of gains: 21; Total number of losses: 150; Total Number of normals: 317.
Somatic mutations of PPP2R2B:
Generating mutation plots.
Highly correlated genes for PPP2R2B:
Showing top 20/416 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP2R2B | PAX3 | 0.767597 | 3 | 0 | 3 |
| PPP2R2B | C1orf61 | 0.740415 | 3 | 0 | 3 |
| PPP2R2B | ZNF81 | 0.715733 | 3 | 0 | 3 |
| PPP2R2B | TTBK1 | 0.706793 | 3 | 0 | 3 |
| PPP2R2B | FBXO24 | 0.70422 | 4 | 0 | 4 |
| PPP2R2B | PNLIPRP1 | 0.698846 | 5 | 0 | 5 |
| PPP2R2B | CALCR | 0.692783 | 4 | 0 | 4 |
| PPP2R2B | LAT | 0.692326 | 3 | 0 | 3 |
| PPP2R2B | NXNL1 | 0.690751 | 3 | 0 | 3 |
| PPP2R2B | KIF17 | 0.689925 | 3 | 0 | 3 |
| PPP2R2B | NNAT | 0.687457 | 5 | 0 | 5 |
| PPP2R2B | CHRND | 0.684342 | 4 | 0 | 4 |
| PPP2R2B | MYOG | 0.683917 | 3 | 0 | 3 |
| PPP2R2B | BTBD9 | 0.682325 | 3 | 0 | 3 |
| PPP2R2B | ROS1 | 0.679867 | 3 | 0 | 3 |
| PPP2R2B | PGAM2 | 0.676949 | 3 | 0 | 3 |
| PPP2R2B | AIRE | 0.674995 | 5 | 0 | 5 |
| PPP2R2B | ENGASE | 0.674509 | 3 | 0 | 3 |
| PPP2R2B | FUT7 | 0.67416 | 4 | 0 | 4 |
| PPP2R2B | GATA2 | 0.669563 | 3 | 0 | 3 |
For details and further investigation, click here
