| Full name: FCH and double SH3 domains 1 | Alias Symbol: FLJ00007 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 89848 | HGNC ID: HGNC:25463 | Ensembl Gene: ENSG00000197948 | OMIM ID: 617555 |
| Drug and gene relationship at DGIdb | |||
Expression of FCHSD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCHSD1 | 89848 | 226698_at | 0.0514 | 0.8648 | |
| GSE26886 | FCHSD1 | 89848 | 226698_at | -0.1746 | 0.2593 | |
| GSE45670 | FCHSD1 | 89848 | 226698_at | 0.7016 | 0.0280 | |
| GSE53622 | FCHSD1 | 89848 | 11229 | 0.3746 | 0.0038 | |
| GSE53624 | FCHSD1 | 89848 | 11229 | 0.5590 | 0.0000 | |
| GSE63941 | FCHSD1 | 89848 | 226698_at | -0.3502 | 0.3627 | |
| GSE77861 | FCHSD1 | 89848 | 226699_at | 0.0199 | 0.8600 | |
| GSE97050 | FCHSD1 | 89848 | A_23_P343826 | 0.1772 | 0.3791 | |
| SRP007169 | FCHSD1 | 89848 | RNAseq | -0.0082 | 0.9906 | |
| SRP064894 | FCHSD1 | 89848 | RNAseq | 0.3967 | 0.0090 | |
| SRP133303 | FCHSD1 | 89848 | RNAseq | -0.3371 | 0.0508 | |
| SRP159526 | FCHSD1 | 89848 | RNAseq | -0.5396 | 0.1956 | |
| SRP193095 | FCHSD1 | 89848 | RNAseq | 0.5177 | 0.0029 | |
| SRP219564 | FCHSD1 | 89848 | RNAseq | -0.3517 | 0.3605 | |
| TCGA | FCHSD1 | 89848 | RNAseq | -0.0007 | 0.9953 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FCHSD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCHSD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCHSD1 | 89848 | 2 | 11 | 17 | |
| GSE20123 | FCHSD1 | 89848 | 3 | 11 | 16 | |
| GSE43470 | FCHSD1 | 89848 | 2 | 10 | 31 | |
| GSE46452 | FCHSD1 | 89848 | 0 | 27 | 32 | |
| GSE47630 | FCHSD1 | 89848 | 1 | 19 | 20 | |
| GSE54993 | FCHSD1 | 89848 | 9 | 1 | 60 | |
| GSE54994 | FCHSD1 | 89848 | 2 | 14 | 37 | |
| GSE60625 | FCHSD1 | 89848 | 0 | 0 | 11 | |
| GSE74703 | FCHSD1 | 89848 | 2 | 7 | 27 | |
| GSE74704 | FCHSD1 | 89848 | 2 | 5 | 13 | |
| TCGA | FCHSD1 | 89848 | 3 | 38 | 55 |
Total number of gains: 26; Total number of losses: 143; Total Number of normals: 319.
Somatic mutations of FCHSD1:
Generating mutation plots.
Highly correlated genes for FCHSD1:
Showing top 20/48 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCHSD1 | ZSWIM3 | 0.734211 | 3 | 0 | 3 |
| FCHSD1 | G6PD | 0.734065 | 3 | 0 | 3 |
| FCHSD1 | SPATA2L | 0.699119 | 3 | 0 | 3 |
| FCHSD1 | ATAD3C | 0.669848 | 3 | 0 | 3 |
| FCHSD1 | TTPAL | 0.656664 | 4 | 0 | 3 |
| FCHSD1 | ALOX12B | 0.655222 | 4 | 0 | 3 |
| FCHSD1 | AXIN1 | 0.649656 | 4 | 0 | 3 |
| FCHSD1 | KPTN | 0.647869 | 3 | 0 | 3 |
| FCHSD1 | TPH1 | 0.639101 | 3 | 0 | 3 |
| FCHSD1 | GPSM3 | 0.638471 | 3 | 0 | 3 |
| FCHSD1 | SPAG4 | 0.633909 | 6 | 0 | 5 |
| FCHSD1 | SIRT6 | 0.630438 | 4 | 0 | 3 |
| FCHSD1 | PPM1J | 0.62666 | 4 | 0 | 3 |
| FCHSD1 | BPIFC | 0.623876 | 4 | 0 | 3 |
| FCHSD1 | AICDA | 0.623676 | 4 | 0 | 3 |
| FCHSD1 | HOMER1 | 0.61676 | 4 | 0 | 3 |
| FCHSD1 | SPTBN5 | 0.61258 | 4 | 0 | 3 |
| FCHSD1 | APTX | 0.608111 | 4 | 0 | 3 |
| FCHSD1 | GOLGA7B | 0.607858 | 3 | 0 | 3 |
| FCHSD1 | SIL1 | 0.606578 | 5 | 0 | 4 |
For details and further investigation, click here
