| Full name: glucose-6-phosphate dehydrogenase | Alias Symbol: G6PD1 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 2539 | HGNC ID: HGNC:4057 | Ensembl Gene: ENSG00000160211 | OMIM ID: 305900 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of G6PD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | G6PD | 2539 | 202275_at | 0.6352 | 0.4880 | |
| GSE20347 | G6PD | 2539 | 202275_at | 0.4478 | 0.2093 | |
| GSE23400 | G6PD | 2539 | 202275_at | 0.7134 | 0.0004 | |
| GSE26886 | G6PD | 2539 | 202275_at | 0.5191 | 0.1884 | |
| GSE29001 | G6PD | 2539 | 202275_at | -0.0939 | 0.8737 | |
| GSE38129 | G6PD | 2539 | 202275_at | 0.8356 | 0.0032 | |
| GSE45670 | G6PD | 2539 | 202275_at | 0.7953 | 0.0200 | |
| GSE53622 | G6PD | 2539 | 3268 | 0.7350 | 0.0000 | |
| GSE53624 | G6PD | 2539 | 3594 | 0.4722 | 0.0000 | |
| GSE63941 | G6PD | 2539 | 202275_at | 1.2053 | 0.1134 | |
| GSE77861 | G6PD | 2539 | 202275_at | 1.4515 | 0.0832 | |
| GSE97050 | G6PD | 2539 | A_23_P34093 | 0.5609 | 0.1726 | |
| SRP007169 | G6PD | 2539 | RNAseq | 0.6805 | 0.0403 | |
| SRP008496 | G6PD | 2539 | RNAseq | 0.7633 | 0.0257 | |
| SRP064894 | G6PD | 2539 | RNAseq | 0.5558 | 0.0465 | |
| SRP133303 | G6PD | 2539 | RNAseq | 0.4680 | 0.0420 | |
| SRP159526 | G6PD | 2539 | RNAseq | 1.9235 | 0.0021 | |
| SRP193095 | G6PD | 2539 | RNAseq | 0.7875 | 0.0033 | |
| SRP219564 | G6PD | 2539 | RNAseq | 1.3495 | 0.0556 | |
| TCGA | G6PD | 2539 | RNAseq | 0.5091 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by G6PD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of G6PD:
No record found for this gene.
Somatic mutations of G6PD:
Generating mutation plots.
Highly correlated genes for G6PD:
Showing top 20/218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| G6PD | AXIN1 | 0.760224 | 3 | 0 | 3 |
| G6PD | SLC7A11 | 0.747357 | 10 | 0 | 10 |
| G6PD | FCHSD1 | 0.734065 | 3 | 0 | 3 |
| G6PD | CYP4F11 | 0.729966 | 11 | 0 | 11 |
| G6PD | TMEM163 | 0.72074 | 3 | 0 | 3 |
| G6PD | CD70 | 0.712841 | 3 | 0 | 3 |
| G6PD | DGKZ | 0.702772 | 3 | 0 | 3 |
| G6PD | AKR1C2 | 0.692656 | 9 | 0 | 8 |
| G6PD | GCLM | 0.689112 | 10 | 0 | 9 |
| G6PD | AKR1C3 | 0.67963 | 11 | 0 | 11 |
| G6PD | GPX2 | 0.668073 | 12 | 0 | 11 |
| G6PD | NQO1 | 0.666024 | 9 | 0 | 8 |
| G6PD | ADAP1 | 0.663437 | 3 | 0 | 3 |
| G6PD | NKX2-8 | 0.657555 | 3 | 0 | 3 |
| G6PD | POC1A | 0.645611 | 4 | 0 | 4 |
| G6PD | OSGIN1 | 0.642992 | 12 | 0 | 10 |
| G6PD | TRIM11 | 0.641321 | 4 | 0 | 3 |
| G6PD | PPFIA3 | 0.638184 | 4 | 0 | 3 |
| G6PD | PAK6 | 0.635682 | 4 | 0 | 3 |
| G6PD | PANX2 | 0.635346 | 6 | 0 | 5 |
For details and further investigation, click here
