| Full name: protein phosphatase, Mg2+/Mn2+ dependent 1J | Alias Symbol: FLJ35951|MGC19531|DKFZp434P1514|PP2Czeta|PPP2CZ | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 333926 | HGNC ID: HGNC:20785 | Ensembl Gene: ENSG00000155367 | OMIM ID: 609957 |
| Drug and gene relationship at DGIdb | |||
Expression of PPM1J:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPM1J | 333926 | 229484_at | -0.0381 | 0.9228 | |
| GSE26886 | PPM1J | 333926 | 229484_at | -0.1575 | 0.3684 | |
| GSE45670 | PPM1J | 333926 | 229484_at | 0.1051 | 0.2804 | |
| GSE53622 | PPM1J | 333926 | 6715 | -0.1289 | 0.4330 | |
| GSE53624 | PPM1J | 333926 | 6715 | 0.2061 | 0.0711 | |
| GSE63941 | PPM1J | 333926 | 229484_at | 0.5797 | 0.1458 | |
| GSE77861 | PPM1J | 333926 | 229484_at | -0.0339 | 0.8474 | |
| GSE97050 | PPM1J | 333926 | A_23_P201939 | 0.0349 | 0.8812 | |
| SRP007169 | PPM1J | 333926 | RNAseq | 0.0424 | 0.9347 | |
| SRP064894 | PPM1J | 333926 | RNAseq | 0.3165 | 0.2525 | |
| SRP133303 | PPM1J | 333926 | RNAseq | -0.5126 | 0.0838 | |
| SRP159526 | PPM1J | 333926 | RNAseq | -0.6283 | 0.1583 | |
| SRP219564 | PPM1J | 333926 | RNAseq | -0.9697 | 0.0385 | |
| TCGA | PPM1J | 333926 | RNAseq | 0.7467 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPM1J expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPM1J:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPM1J | 333926 | 0 | 10 | 20 | |
| GSE20123 | PPM1J | 333926 | 0 | 10 | 20 | |
| GSE43470 | PPM1J | 333926 | 0 | 8 | 35 | |
| GSE46452 | PPM1J | 333926 | 2 | 1 | 56 | |
| GSE47630 | PPM1J | 333926 | 9 | 5 | 26 | |
| GSE54993 | PPM1J | 333926 | 0 | 1 | 69 | |
| GSE54994 | PPM1J | 333926 | 7 | 4 | 42 | |
| GSE60625 | PPM1J | 333926 | 0 | 0 | 11 | |
| GSE74703 | PPM1J | 333926 | 0 | 7 | 29 | |
| GSE74704 | PPM1J | 333926 | 0 | 6 | 14 | |
| TCGA | PPM1J | 333926 | 8 | 27 | 61 |
Total number of gains: 26; Total number of losses: 79; Total Number of normals: 383.
Somatic mutations of PPM1J:
Generating mutation plots.
Highly correlated genes for PPM1J:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPM1J | ABCA2 | 0.788542 | 3 | 0 | 3 |
| PPM1J | TEKT2 | 0.752264 | 3 | 0 | 3 |
| PPM1J | CCL17 | 0.743166 | 3 | 0 | 3 |
| PPM1J | LTC4S | 0.725192 | 3 | 0 | 3 |
| PPM1J | FERD3L | 0.722941 | 3 | 0 | 3 |
| PPM1J | ITGA2B | 0.717219 | 3 | 0 | 3 |
| PPM1J | B9D1 | 0.71534 | 4 | 0 | 3 |
| PPM1J | CELF4 | 0.714869 | 3 | 0 | 3 |
| PPM1J | AKR7A3 | 0.703484 | 4 | 0 | 3 |
| PPM1J | CALHM3 | 0.703124 | 3 | 0 | 3 |
| PPM1J | GPR17 | 0.695937 | 4 | 0 | 4 |
| PPM1J | APOM | 0.694876 | 3 | 0 | 3 |
| PPM1J | ARMC7 | 0.692133 | 4 | 0 | 3 |
| PPM1J | HOXB5 | 0.689315 | 3 | 0 | 3 |
| PPM1J | LRRC46 | 0.688111 | 3 | 0 | 3 |
| PPM1J | LRFN2 | 0.686656 | 3 | 0 | 3 |
| PPM1J | SCARF2 | 0.685364 | 3 | 0 | 3 |
| PPM1J | TMEM52 | 0.684708 | 3 | 0 | 3 |
| PPM1J | IPO13 | 0.6789 | 3 | 0 | 3 |
| PPM1J | ADH6 | 0.676861 | 3 | 0 | 3 |
For details and further investigation, click here
