| Full name: kaptin, actin binding protein | Alias Symbol: 2E4 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 11133 | HGNC ID: HGNC:6404 | Ensembl Gene: ENSG00000118162 | OMIM ID: 615620 |
| Drug and gene relationship at DGIdb | |||
Expression of KPTN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KPTN | 11133 | 220160_s_at | 0.4967 | 0.1030 | |
| GSE20347 | KPTN | 11133 | 220160_s_at | 0.1770 | 0.1301 | |
| GSE23400 | KPTN | 11133 | 220160_s_at | 0.1121 | 0.0248 | |
| GSE26886 | KPTN | 11133 | 220160_s_at | 0.5990 | 0.0055 | |
| GSE29001 | KPTN | 11133 | 220160_s_at | 0.2604 | 0.3336 | |
| GSE38129 | KPTN | 11133 | 220160_s_at | 0.3472 | 0.0009 | |
| GSE45670 | KPTN | 11133 | 220160_s_at | 0.4639 | 0.0014 | |
| GSE53622 | KPTN | 11133 | 5970 | 0.3661 | 0.0047 | |
| GSE53624 | KPTN | 11133 | 5970 | 0.6981 | 0.0000 | |
| GSE63941 | KPTN | 11133 | 220160_s_at | 0.6196 | 0.1864 | |
| GSE77861 | KPTN | 11133 | 220160_s_at | 0.0947 | 0.6998 | |
| GSE97050 | KPTN | 11133 | A_23_P67391 | -0.0584 | 0.9270 | |
| SRP007169 | KPTN | 11133 | RNAseq | -0.0323 | 0.9479 | |
| SRP064894 | KPTN | 11133 | RNAseq | 1.1181 | 0.0001 | |
| SRP133303 | KPTN | 11133 | RNAseq | 0.4585 | 0.0578 | |
| SRP159526 | KPTN | 11133 | RNAseq | 0.9874 | 0.0085 | |
| SRP193095 | KPTN | 11133 | RNAseq | 0.2365 | 0.0591 | |
| SRP219564 | KPTN | 11133 | RNAseq | 0.7189 | 0.0199 | |
| TCGA | KPTN | 11133 | RNAseq | 0.4535 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KPTN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KPTN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KPTN | 11133 | 4 | 4 | 22 | |
| GSE20123 | KPTN | 11133 | 4 | 3 | 23 | |
| GSE43470 | KPTN | 11133 | 3 | 10 | 30 | |
| GSE46452 | KPTN | 11133 | 45 | 1 | 13 | |
| GSE47630 | KPTN | 11133 | 8 | 7 | 25 | |
| GSE54993 | KPTN | 11133 | 17 | 4 | 49 | |
| GSE54994 | KPTN | 11133 | 4 | 14 | 35 | |
| GSE60625 | KPTN | 11133 | 9 | 0 | 2 | |
| GSE74703 | KPTN | 11133 | 3 | 7 | 26 | |
| GSE74704 | KPTN | 11133 | 4 | 1 | 15 | |
| TCGA | KPTN | 11133 | 14 | 18 | 64 |
Total number of gains: 115; Total number of losses: 69; Total Number of normals: 304.
Somatic mutations of KPTN:
Generating mutation plots.
Highly correlated genes for KPTN:
Showing top 20/345 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KPTN | FASTKD3 | 0.738489 | 3 | 0 | 3 |
| KPTN | RAC3 | 0.737247 | 3 | 0 | 3 |
| KPTN | NAPSA | 0.721961 | 3 | 0 | 3 |
| KPTN | UCN2 | 0.69228 | 3 | 0 | 3 |
| KPTN | ZNF628 | 0.680299 | 4 | 0 | 3 |
| KPTN | FMNL2 | 0.658722 | 3 | 0 | 3 |
| KPTN | TANGO2 | 0.656545 | 3 | 0 | 3 |
| KPTN | MYH10 | 0.654355 | 3 | 0 | 3 |
| KPTN | PPARD | 0.653788 | 4 | 0 | 4 |
| KPTN | INO80B | 0.651316 | 3 | 0 | 3 |
| KPTN | FCHSD1 | 0.647869 | 3 | 0 | 3 |
| KPTN | RUVBL2 | 0.645988 | 10 | 0 | 9 |
| KPTN | ZNF581 | 0.634841 | 3 | 0 | 3 |
| KPTN | FANCE | 0.631771 | 5 | 0 | 4 |
| KPTN | ASPHD1 | 0.630344 | 4 | 0 | 3 |
| KPTN | RTTN | 0.62419 | 4 | 0 | 4 |
| KPTN | INTS1 | 0.622968 | 8 | 0 | 5 |
| KPTN | DBN1 | 0.622689 | 3 | 0 | 3 |
| KPTN | ICE1 | 0.621848 | 5 | 0 | 4 |
| KPTN | OBSCN | 0.617606 | 5 | 0 | 4 |
For details and further investigation, click here
