| Full name: fibroblast growth factor 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.21 | ||
| Entrez ID: 2250 | HGNC ID: HGNC:3683 | Ensembl Gene: ENSG00000138675 | OMIM ID: 165190 |
| Drug and gene relationship at DGIdb | |||
FGF5 involved pathways:
Expression of FGF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGF5 | 2250 | 208378_x_at | 0.0676 | 0.7917 | |
| GSE20347 | FGF5 | 2250 | 210310_s_at | -0.0411 | 0.5886 | |
| GSE23400 | FGF5 | 2250 | 208378_x_at | -0.0619 | 0.0850 | |
| GSE26886 | FGF5 | 2250 | 210311_at | -0.3655 | 0.0112 | |
| GSE29001 | FGF5 | 2250 | 208378_x_at | -0.0857 | 0.6860 | |
| GSE38129 | FGF5 | 2250 | 210310_s_at | -0.1010 | 0.1137 | |
| GSE45670 | FGF5 | 2250 | 210310_s_at | 0.0536 | 0.4879 | |
| GSE53622 | FGF5 | 2250 | 116367 | -1.0561 | 0.0000 | |
| GSE53624 | FGF5 | 2250 | 116367 | -1.5911 | 0.0000 | |
| GSE63941 | FGF5 | 2250 | 210310_s_at | -1.4213 | 0.0084 | |
| GSE77861 | FGF5 | 2250 | 210310_s_at | -0.1632 | 0.1651 | |
| GSE97050 | FGF5 | 2250 | A_33_P3411907 | -1.1764 | 0.1075 | |
| SRP007169 | FGF5 | 2250 | RNAseq | -1.5584 | 0.0188 | |
| SRP064894 | FGF5 | 2250 | RNAseq | -2.9116 | 0.0000 | |
| SRP133303 | FGF5 | 2250 | RNAseq | -1.2897 | 0.0000 | |
| SRP159526 | FGF5 | 2250 | RNAseq | -4.0331 | 0.0000 | |
| SRP193095 | FGF5 | 2250 | RNAseq | -1.4935 | 0.0000 | |
| SRP219564 | FGF5 | 2250 | RNAseq | -2.5739 | 0.0000 | |
| TCGA | FGF5 | 2250 | RNAseq | -0.1913 | 0.7177 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by FGF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGF5 | 2250 | 0 | 10 | 20 | |
| GSE20123 | FGF5 | 2250 | 1 | 10 | 19 | |
| GSE43470 | FGF5 | 2250 | 0 | 13 | 30 | |
| GSE46452 | FGF5 | 2250 | 1 | 36 | 22 | |
| GSE47630 | FGF5 | 2250 | 1 | 19 | 20 | |
| GSE54993 | FGF5 | 2250 | 8 | 0 | 62 | |
| GSE54994 | FGF5 | 2250 | 0 | 9 | 44 | |
| GSE60625 | FGF5 | 2250 | 0 | 0 | 11 | |
| GSE74703 | FGF5 | 2250 | 0 | 11 | 25 | |
| GSE74704 | FGF5 | 2250 | 1 | 5 | 14 | |
| TCGA | FGF5 | 2250 | 11 | 34 | 51 |
Total number of gains: 23; Total number of losses: 147; Total Number of normals: 318.
Somatic mutations of FGF5:
Generating mutation plots.
Highly correlated genes for FGF5:
Showing top 20/511 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGF5 | HES5 | 0.906329 | 3 | 0 | 3 |
| FGF5 | FAM163B | 0.886289 | 3 | 0 | 3 |
| FGF5 | KRTAP20-1 | 0.864425 | 3 | 0 | 3 |
| FGF5 | OR2Z1 | 0.831409 | 3 | 0 | 3 |
| FGF5 | MFSD2B | 0.808125 | 3 | 0 | 3 |
| FGF5 | BARHL2 | 0.804624 | 3 | 0 | 3 |
| FGF5 | MUC22 | 0.797027 | 3 | 0 | 3 |
| FGF5 | NCCRP1 | 0.792597 | 3 | 0 | 3 |
| FGF5 | OR10G8 | 0.773438 | 3 | 0 | 3 |
| FGF5 | DHRS7C | 0.773123 | 3 | 0 | 3 |
| FGF5 | OTOP3 | 0.770668 | 3 | 0 | 3 |
| FGF5 | KPRP | 0.769171 | 3 | 0 | 3 |
| FGF5 | TEN1 | 0.764782 | 3 | 0 | 3 |
| FGF5 | MAFG | 0.75514 | 4 | 0 | 4 |
| FGF5 | ACOT8 | 0.75302 | 4 | 0 | 4 |
| FGF5 | GPX6 | 0.743745 | 3 | 0 | 3 |
| FGF5 | RNF222 | 0.740056 | 3 | 0 | 3 |
| FGF5 | TMPRSS11A | 0.739554 | 3 | 0 | 3 |
| FGF5 | KCNA7 | 0.739412 | 4 | 0 | 4 |
| FGF5 | CGA | 0.735585 | 3 | 0 | 3 |
For details and further investigation, click here
