| Full name: CD79a molecule | Alias Symbol: MB-1 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 973 | HGNC ID: HGNC:1698 | Ensembl Gene: ENSG00000105369 | OMIM ID: 112205 |
| Drug and gene relationship at DGIdb | |||
CD79A involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04662 | B cell receptor signaling pathway |
Expression of CD79A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD79A | 973 | 205049_s_at | -0.0991 | 0.9592 | |
| GSE20347 | CD79A | 973 | 205049_s_at | 0.0932 | 0.6757 | |
| GSE23400 | CD79A | 973 | 205049_s_at | -0.1252 | 0.1375 | |
| GSE26886 | CD79A | 973 | 205049_s_at | 0.1599 | 0.3660 | |
| GSE29001 | CD79A | 973 | 205049_s_at | -0.3034 | 0.1518 | |
| GSE38129 | CD79A | 973 | 205049_s_at | 0.0387 | 0.8984 | |
| GSE45670 | CD79A | 973 | 1555779_a_at | -0.0666 | 0.5956 | |
| GSE53622 | CD79A | 973 | 24813 | -0.1566 | 0.4927 | |
| GSE53624 | CD79A | 973 | 24813 | -0.7183 | 0.0000 | |
| GSE63941 | CD79A | 973 | 1555779_a_at | 0.1181 | 0.5158 | |
| GSE77861 | CD79A | 973 | 1555779_a_at | -0.0861 | 0.4007 | |
| GSE97050 | CD79A | 973 | A_23_P107735 | 1.2960 | 0.1726 | |
| SRP064894 | CD79A | 973 | RNAseq | 0.4398 | 0.3881 | |
| SRP133303 | CD79A | 973 | RNAseq | -0.3958 | 0.5303 | |
| SRP159526 | CD79A | 973 | RNAseq | -0.4219 | 0.7839 | |
| SRP219564 | CD79A | 973 | RNAseq | 1.3601 | 0.0464 | |
| TCGA | CD79A | 973 | RNAseq | -0.5563 | 0.1199 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CD79A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD79A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD79A | 973 | 4 | 4 | 22 | |
| GSE20123 | CD79A | 973 | 4 | 3 | 23 | |
| GSE43470 | CD79A | 973 | 3 | 11 | 29 | |
| GSE46452 | CD79A | 973 | 47 | 1 | 11 | |
| GSE47630 | CD79A | 973 | 8 | 6 | 26 | |
| GSE54993 | CD79A | 973 | 17 | 4 | 49 | |
| GSE54994 | CD79A | 973 | 7 | 12 | 34 | |
| GSE60625 | CD79A | 973 | 9 | 0 | 2 | |
| GSE74703 | CD79A | 973 | 3 | 7 | 26 | |
| GSE74704 | CD79A | 973 | 4 | 1 | 15 | |
| TCGA | CD79A | 973 | 14 | 15 | 67 |
Total number of gains: 120; Total number of losses: 64; Total Number of normals: 304.
Somatic mutations of CD79A:
Generating mutation plots.
Highly correlated genes for CD79A:
Showing top 20/306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD79A | POU2AF1 | 0.762582 | 4 | 0 | 4 |
| CD79A | FCRL5 | 0.760656 | 6 | 0 | 5 |
| CD79A | FCRL1 | 0.756082 | 5 | 0 | 5 |
| CD79A | FCRL3 | 0.732356 | 7 | 0 | 7 |
| CD79A | SH3BP1 | 0.728695 | 3 | 0 | 3 |
| CD79A | SLAMF6 | 0.723842 | 6 | 0 | 6 |
| CD79A | GPR174 | 0.718663 | 3 | 0 | 3 |
| CD79A | CD19 | 0.716281 | 11 | 0 | 11 |
| CD79A | INO80B | 0.712142 | 3 | 0 | 3 |
| CD79A | MZB1 | 0.710664 | 10 | 0 | 8 |
| CD79A | FGF6 | 0.70957 | 3 | 0 | 3 |
| CD79A | CLEC17A | 0.70928 | 3 | 0 | 3 |
| CD79A | SPIB | 0.709102 | 8 | 0 | 7 |
| CD79A | PNOC | 0.705149 | 8 | 0 | 6 |
| CD79A | TNFRSF17 | 0.698308 | 10 | 0 | 8 |
| CD79A | BANK1 | 0.69556 | 10 | 0 | 8 |
| CD79A | COL18A1-AS1 | 0.693894 | 3 | 0 | 3 |
| CD79A | SASH3 | 0.691698 | 9 | 0 | 8 |
| CD79A | OPCML | 0.691411 | 3 | 0 | 3 |
| CD79A | PTPRCAP | 0.689813 | 9 | 0 | 7 |
For details and further investigation, click here
