| Full name: FKBP prolyl isomerase 3 | Alias Symbol: FKBP-25|FKBP25 | ||
| Type: protein-coding gene | Cytoband: 14q21.2 | ||
| Entrez ID: 2287 | HGNC ID: HGNC:3719 | Ensembl Gene: ENSG00000100442 | OMIM ID: 186947 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FKBP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKBP3 | 2287 | 218003_s_at | -0.2838 | 0.6089 | |
| GSE20347 | FKBP3 | 2287 | 218003_s_at | -0.2273 | 0.1314 | |
| GSE23400 | FKBP3 | 2287 | 218003_s_at | 0.3875 | 0.0000 | |
| GSE26886 | FKBP3 | 2287 | 218003_s_at | 0.6135 | 0.0090 | |
| GSE29001 | FKBP3 | 2287 | 218003_s_at | 0.0919 | 0.7519 | |
| GSE38129 | FKBP3 | 2287 | 218003_s_at | 0.0365 | 0.7932 | |
| GSE45670 | FKBP3 | 2287 | 218003_s_at | 0.2461 | 0.0448 | |
| GSE53622 | FKBP3 | 2287 | 63222 | -0.0437 | 0.5311 | |
| GSE53624 | FKBP3 | 2287 | 63222 | 0.2556 | 0.0006 | |
| GSE63941 | FKBP3 | 2287 | 218003_s_at | 0.7322 | 0.1301 | |
| GSE77861 | FKBP3 | 2287 | 218003_s_at | 0.0457 | 0.9216 | |
| GSE97050 | FKBP3 | 2287 | A_23_P117558 | -0.3504 | 0.3311 | |
| SRP007169 | FKBP3 | 2287 | RNAseq | 0.8822 | 0.0549 | |
| SRP008496 | FKBP3 | 2287 | RNAseq | 0.5344 | 0.1851 | |
| SRP064894 | FKBP3 | 2287 | RNAseq | 0.3847 | 0.0687 | |
| SRP133303 | FKBP3 | 2287 | RNAseq | 0.1776 | 0.4118 | |
| SRP159526 | FKBP3 | 2287 | RNAseq | 0.2964 | 0.4206 | |
| SRP193095 | FKBP3 | 2287 | RNAseq | -0.3167 | 0.0650 | |
| SRP219564 | FKBP3 | 2287 | RNAseq | 0.1587 | 0.5925 | |
| TCGA | FKBP3 | 2287 | RNAseq | 0.2072 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FKBP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKBP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKBP3 | 2287 | 6 | 5 | 19 | |
| GSE20123 | FKBP3 | 2287 | 6 | 5 | 19 | |
| GSE43470 | FKBP3 | 2287 | 8 | 3 | 32 | |
| GSE46452 | FKBP3 | 2287 | 17 | 2 | 40 | |
| GSE47630 | FKBP3 | 2287 | 11 | 10 | 19 | |
| GSE54993 | FKBP3 | 2287 | 3 | 9 | 58 | |
| GSE54994 | FKBP3 | 2287 | 18 | 5 | 30 | |
| GSE60625 | FKBP3 | 2287 | 0 | 2 | 9 | |
| GSE74703 | FKBP3 | 2287 | 7 | 3 | 26 | |
| GSE74704 | FKBP3 | 2287 | 3 | 3 | 14 | |
| TCGA | FKBP3 | 2287 | 31 | 15 | 50 |
Total number of gains: 110; Total number of losses: 62; Total Number of normals: 316.
Somatic mutations of FKBP3:
Generating mutation plots.
Highly correlated genes for FKBP3:
Showing top 20/292 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKBP3 | FRA10AC1 | 0.75133 | 3 | 0 | 3 |
| FKBP3 | BTF3L4 | 0.740898 | 3 | 0 | 3 |
| FKBP3 | YWHAG | 0.732779 | 3 | 0 | 3 |
| FKBP3 | COX16 | 0.711926 | 5 | 0 | 5 |
| FKBP3 | NPHP3 | 0.682195 | 3 | 0 | 3 |
| FKBP3 | RPL24 | 0.682061 | 3 | 0 | 3 |
| FKBP3 | FAHD1 | 0.6815 | 3 | 0 | 3 |
| FKBP3 | SLU7 | 0.679308 | 3 | 0 | 3 |
| FKBP3 | CYTH2 | 0.675072 | 3 | 0 | 3 |
| FKBP3 | ANAPC4 | 0.657754 | 3 | 0 | 3 |
| FKBP3 | CWC22 | 0.655236 | 4 | 0 | 3 |
| FKBP3 | UBE2E1 | 0.648817 | 3 | 0 | 3 |
| FKBP3 | ZNF558 | 0.644309 | 3 | 0 | 3 |
| FKBP3 | YY1 | 0.643422 | 9 | 0 | 8 |
| FKBP3 | SCRN3 | 0.640039 | 3 | 0 | 3 |
| FKBP3 | NAA30 | 0.63778 | 6 | 0 | 5 |
| FKBP3 | MNAT1 | 0.637214 | 9 | 0 | 8 |
| FKBP3 | CAP1 | 0.634798 | 4 | 0 | 3 |
| FKBP3 | CHURC1 | 0.632943 | 7 | 0 | 6 |
| FKBP3 | FH | 0.631181 | 3 | 0 | 3 |
For details and further investigation, click here
