MNAT1

 

Full name: MNAT1 component of CDK activating kinase Alias Symbol: MAT1|RNF66
Type: protein-coding gene Cytoband: 14q23.1
Entrez ID: 4331 HGNC ID: HGNC:7181 Ensembl Gene: ENSG00000020426 OMIM ID: 602659
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MNAT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MNAT1 4331 203565_s_at 0.5789 0.1713
GSE20347 MNAT1 4331 203565_s_at 1.0134 0.0000
GSE23400 MNAT1 4331 203565_s_at 0.6513 0.0000
GSE26886 MNAT1 4331 203565_s_at 1.4141 0.0000
GSE29001 MNAT1 4331 203565_s_at 0.7805 0.0199
GSE38129 MNAT1 4331 203565_s_at 0.8939 0.0000
GSE45670 MNAT1 4331 203565_s_at 0.5514 0.0066
GSE53622 MNAT1 4331 15676 0.6905 0.0000
GSE53624 MNAT1 4331 15676 0.9135 0.0000
GSE63941 MNAT1 4331 203565_s_at 0.7428 0.2219
GSE77861 MNAT1 4331 203565_s_at 0.7182 0.1097
GSE97050 MNAT1 4331 A_23_P32615 0.4078 0.2501
SRP007169 MNAT1 4331 RNAseq 0.8692 0.0297
SRP008496 MNAT1 4331 RNAseq 1.0448 0.0001
SRP064894 MNAT1 4331 RNAseq 0.7226 0.0000
SRP133303 MNAT1 4331 RNAseq 0.8477 0.0000
SRP159526 MNAT1 4331 RNAseq 0.6834 0.0497
SRP193095 MNAT1 4331 RNAseq 0.5498 0.0002
SRP219564 MNAT1 4331 RNAseq 0.5518 0.1451
TCGA MNAT1 4331 RNAseq 0.3152 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by MNAT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MNAT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MNAT1 4331 9 3 18
GSE20123 MNAT1 4331 8 3 19
GSE43470 MNAT1 4331 8 2 33
GSE46452 MNAT1 4331 16 3 40
GSE47630 MNAT1 4331 11 9 20
GSE54993 MNAT1 4331 3 9 58
GSE54994 MNAT1 4331 19 4 30
GSE60625 MNAT1 4331 0 2 9
GSE74703 MNAT1 4331 7 2 27
GSE74704 MNAT1 4331 4 2 14
TCGA MNAT1 4331 32 14 50

Total number of gains: 117; Total number of losses: 53; Total Number of normals: 318.  

 

Somatic mutations of MNAT1:

 

Generating mutation plots.

 

Highly correlated genes for MNAT1:

 

Showing top 20/1875 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MNAT1TIMM90.82544413013
MNAT1FMR10.81255303
MNAT1ZNF7070.788414303
MNAT1WDR540.786494606
MNAT1ATP11C0.772509303
MNAT1SLC38A60.76405311010
MNAT1PSMC10.76238210010
MNAT1JKAMP0.760688605
MNAT1PSMA30.76049511011
MNAT1EXOC60.758394303
MNAT1ZSCAN210.75583404
MNAT1KTN10.75541112012
MNAT1CDKN30.75172613012
MNAT1ERH0.75155612012
MNAT1G2E30.749033605
MNAT1ZNF6270.745838303
MNAT1TMTC10.743612303
MNAT1MRPS50.741694403
MNAT1ATP6V1C10.74102210010
MNAT1WDHD10.74069813012

For details and further investigation, click here