| Full name: fumarylacetoacetate hydrolase domain containing 1 | Alias Symbol: DKFZP566J2046 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 81889 | HGNC ID: HGNC:14169 | Ensembl Gene: ENSG00000180185 | OMIM ID: 616320 |
| Drug and gene relationship at DGIdb | |||
Expression of FAHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAHD1 | 81889 | 227960_s_at | -0.5279 | 0.5859 | |
| GSE26886 | FAHD1 | 81889 | 227960_s_at | 0.1763 | 0.5093 | |
| GSE45670 | FAHD1 | 81889 | 227960_s_at | 0.2053 | 0.2459 | |
| GSE53622 | FAHD1 | 81889 | 115129 | -0.1186 | 0.1111 | |
| GSE53624 | FAHD1 | 81889 | 115129 | -0.2417 | 0.0013 | |
| GSE63941 | FAHD1 | 81889 | 227960_s_at | 0.0532 | 0.9348 | |
| GSE77861 | FAHD1 | 81889 | 227960_s_at | -0.1335 | 0.8384 | |
| GSE97050 | FAHD1 | 81889 | A_23_P118300 | -0.2618 | 0.2526 | |
| SRP007169 | FAHD1 | 81889 | RNAseq | -0.5334 | 0.2346 | |
| SRP008496 | FAHD1 | 81889 | RNAseq | -0.5035 | 0.0437 | |
| SRP064894 | FAHD1 | 81889 | RNAseq | -0.2960 | 0.0961 | |
| SRP133303 | FAHD1 | 81889 | RNAseq | 0.1595 | 0.5008 | |
| SRP159526 | FAHD1 | 81889 | RNAseq | -0.1495 | 0.5965 | |
| SRP193095 | FAHD1 | 81889 | RNAseq | -0.5832 | 0.0000 | |
| SRP219564 | FAHD1 | 81889 | RNAseq | -0.2464 | 0.1672 | |
| TCGA | FAHD1 | 81889 | RNAseq | 0.0833 | 0.1745 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAHD1 | 81889 | 5 | 5 | 20 | |
| GSE20123 | FAHD1 | 81889 | 5 | 4 | 21 | |
| GSE43470 | FAHD1 | 81889 | 4 | 7 | 32 | |
| GSE46452 | FAHD1 | 81889 | 38 | 1 | 20 | |
| GSE47630 | FAHD1 | 81889 | 13 | 6 | 21 | |
| GSE54993 | FAHD1 | 81889 | 3 | 5 | 62 | |
| GSE54994 | FAHD1 | 81889 | 6 | 8 | 39 | |
| GSE60625 | FAHD1 | 81889 | 4 | 0 | 7 | |
| GSE74703 | FAHD1 | 81889 | 4 | 5 | 27 | |
| GSE74704 | FAHD1 | 81889 | 3 | 2 | 15 | |
| TCGA | FAHD1 | 81889 | 19 | 14 | 63 |
Total number of gains: 104; Total number of losses: 57; Total Number of normals: 327.
Somatic mutations of FAHD1:
Generating mutation plots.
Highly correlated genes for FAHD1:
Showing top 20/355 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAHD1 | EIF4G2 | 0.810405 | 3 | 0 | 3 |
| FAHD1 | DYNC1LI2 | 0.806194 | 3 | 0 | 3 |
| FAHD1 | RAB1A | 0.800121 | 3 | 0 | 3 |
| FAHD1 | STAMBP | 0.78667 | 4 | 0 | 4 |
| FAHD1 | HUS1 | 0.776293 | 3 | 0 | 3 |
| FAHD1 | ARL8B | 0.76836 | 4 | 0 | 4 |
| FAHD1 | ACBD3 | 0.764449 | 4 | 0 | 4 |
| FAHD1 | HSPA9 | 0.759374 | 3 | 0 | 3 |
| FAHD1 | DDX1 | 0.754943 | 3 | 0 | 3 |
| FAHD1 | SARNP | 0.741106 | 3 | 0 | 3 |
| FAHD1 | CBR4 | 0.740222 | 3 | 0 | 3 |
| FAHD1 | CUL2 | 0.737272 | 3 | 0 | 3 |
| FAHD1 | ALG13 | 0.73081 | 3 | 0 | 3 |
| FAHD1 | SIN3A | 0.729173 | 3 | 0 | 3 |
| FAHD1 | NKIRAS1 | 0.727281 | 3 | 0 | 3 |
| FAHD1 | PLEKHM3 | 0.727119 | 3 | 0 | 3 |
| FAHD1 | TRIP12 | 0.725844 | 4 | 0 | 3 |
| FAHD1 | MRPS18A | 0.725389 | 3 | 0 | 3 |
| FAHD1 | COMMD8 | 0.722611 | 4 | 0 | 4 |
| FAHD1 | BTBD1 | 0.720311 | 3 | 0 | 3 |
For details and further investigation, click here
