| Full name: YY1 transcription factor | Alias Symbol: NF-E1|DELTA|UCRBP|YIN-YANG-1|INO80S | ||
| Type: protein-coding gene | Cytoband: 14q32.2 | ||
| Entrez ID: 7528 | HGNC ID: HGNC:12856 | Ensembl Gene: ENSG00000100811 | OMIM ID: 600013 |
| Drug and gene relationship at DGIdb | |||
Expression of YY1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YY1 | 7528 | 200047_s_at | 0.4056 | 0.1292 | |
| GSE20347 | YY1 | 7528 | 200047_s_at | 0.3079 | 0.0024 | |
| GSE23400 | YY1 | 7528 | 200047_s_at | 0.5682 | 0.0000 | |
| GSE26886 | YY1 | 7528 | 200047_s_at | 0.2618 | 0.0667 | |
| GSE29001 | YY1 | 7528 | 200047_s_at | 0.3413 | 0.0782 | |
| GSE38129 | YY1 | 7528 | 200047_s_at | 0.4283 | 0.0000 | |
| GSE45670 | YY1 | 7528 | 200047_s_at | 0.2944 | 0.0126 | |
| GSE53622 | YY1 | 7528 | 124604 | 0.1958 | 0.0081 | |
| GSE53624 | YY1 | 7528 | 6743 | 0.4162 | 0.0000 | |
| GSE63941 | YY1 | 7528 | 200047_s_at | 0.2581 | 0.3709 | |
| GSE77861 | YY1 | 7528 | 200047_s_at | 0.0236 | 0.9470 | |
| GSE97050 | YY1 | 7528 | A_33_P3315600 | -0.0255 | 0.9553 | |
| SRP007169 | YY1 | 7528 | RNAseq | -0.1401 | 0.6647 | |
| SRP008496 | YY1 | 7528 | RNAseq | -0.0516 | 0.7670 | |
| SRP064894 | YY1 | 7528 | RNAseq | 0.2506 | 0.0300 | |
| SRP133303 | YY1 | 7528 | RNAseq | 0.3540 | 0.0000 | |
| SRP159526 | YY1 | 7528 | RNAseq | 0.1197 | 0.5825 | |
| SRP193095 | YY1 | 7528 | RNAseq | 0.1052 | 0.2602 | |
| SRP219564 | YY1 | 7528 | RNAseq | -0.0239 | 0.9217 | |
| TCGA | YY1 | 7528 | RNAseq | 0.1259 | 0.0052 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by YY1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YY1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YY1 | 7528 | 9 | 5 | 16 | |
| GSE20123 | YY1 | 7528 | 9 | 4 | 17 | |
| GSE43470 | YY1 | 7528 | 7 | 4 | 32 | |
| GSE46452 | YY1 | 7528 | 17 | 3 | 39 | |
| GSE47630 | YY1 | 7528 | 11 | 8 | 21 | |
| GSE54993 | YY1 | 7528 | 3 | 8 | 59 | |
| GSE54994 | YY1 | 7528 | 21 | 4 | 28 | |
| GSE60625 | YY1 | 7528 | 0 | 2 | 9 | |
| GSE74703 | YY1 | 7528 | 6 | 3 | 27 | |
| GSE74704 | YY1 | 7528 | 5 | 3 | 12 | |
| TCGA | YY1 | 7528 | 31 | 18 | 47 |
Total number of gains: 119; Total number of losses: 62; Total Number of normals: 307.
Somatic mutations of YY1:
Generating mutation plots.
Highly correlated genes for YY1:
Showing top 20/1094 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YY1 | KPNB1 | 0.768 | 3 | 0 | 3 |
| YY1 | NOSIP | 0.766836 | 3 | 0 | 3 |
| YY1 | SLC7A6OS | 0.764211 | 3 | 0 | 3 |
| YY1 | LRRC58 | 0.747513 | 4 | 0 | 4 |
| YY1 | HEATR5A | 0.746365 | 3 | 0 | 3 |
| YY1 | ALG1 | 0.745221 | 3 | 0 | 3 |
| YY1 | TMEM14B | 0.742012 | 3 | 0 | 3 |
| YY1 | LEMD2 | 0.738912 | 3 | 0 | 3 |
| YY1 | AHCY | 0.738502 | 4 | 0 | 4 |
| YY1 | PIGK | 0.731414 | 4 | 0 | 3 |
| YY1 | VPS35 | 0.731308 | 3 | 0 | 3 |
| YY1 | UTP3 | 0.729165 | 3 | 0 | 3 |
| YY1 | LARS2 | 0.726501 | 4 | 0 | 4 |
| YY1 | OSBPL9 | 0.721046 | 4 | 0 | 4 |
| YY1 | BPNT1 | 0.719371 | 4 | 0 | 3 |
| YY1 | RCOR1 | 0.717525 | 4 | 0 | 4 |
| YY1 | HSPB11 | 0.716108 | 6 | 0 | 5 |
| YY1 | CDK5RAP2 | 0.71566 | 3 | 0 | 3 |
| YY1 | MRPS6 | 0.715108 | 4 | 0 | 3 |
| YY1 | CEBPZ | 0.714106 | 5 | 0 | 5 |
For details and further investigation, click here
