| Full name: secernin 3 | Alias Symbol: FLJ23142 | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 79634 | HGNC ID: HGNC:30382 | Ensembl Gene: ENSG00000144306 | OMIM ID: 614967 |
| Drug and gene relationship at DGIdb | |||
Expression of SCRN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCRN3 | 79634 | 222849_s_at | 0.1575 | 0.8758 | |
| GSE20347 | SCRN3 | 79634 | 219234_x_at | 0.0778 | 0.6668 | |
| GSE23400 | SCRN3 | 79634 | 219234_x_at | 0.0477 | 0.4501 | |
| GSE26886 | SCRN3 | 79634 | 222849_s_at | 0.0538 | 0.8518 | |
| GSE29001 | SCRN3 | 79634 | 219234_x_at | -0.0832 | 0.8568 | |
| GSE38129 | SCRN3 | 79634 | 219234_x_at | 0.2482 | 0.1260 | |
| GSE45670 | SCRN3 | 79634 | 222849_s_at | 0.4737 | 0.0148 | |
| GSE53622 | SCRN3 | 79634 | 67863 | -0.1273 | 0.0719 | |
| GSE53624 | SCRN3 | 79634 | 67863 | -0.2241 | 0.0003 | |
| GSE63941 | SCRN3 | 79634 | 222849_s_at | 0.0678 | 0.9136 | |
| GSE77861 | SCRN3 | 79634 | 222849_s_at | -0.0007 | 0.9984 | |
| GSE97050 | SCRN3 | 79634 | A_23_P17021 | -0.3758 | 0.3146 | |
| SRP007169 | SCRN3 | 79634 | RNAseq | -0.8017 | 0.0246 | |
| SRP008496 | SCRN3 | 79634 | RNAseq | -0.7225 | 0.0048 | |
| SRP064894 | SCRN3 | 79634 | RNAseq | -0.3826 | 0.0937 | |
| SRP133303 | SCRN3 | 79634 | RNAseq | -0.0104 | 0.9543 | |
| SRP159526 | SCRN3 | 79634 | RNAseq | -0.2921 | 0.4239 | |
| SRP193095 | SCRN3 | 79634 | RNAseq | -0.4744 | 0.0002 | |
| SRP219564 | SCRN3 | 79634 | RNAseq | -0.7384 | 0.0042 | |
| TCGA | SCRN3 | 79634 | RNAseq | 0.0271 | 0.6689 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCRN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCRN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCRN3 | 79634 | 10 | 0 | 20 | |
| GSE20123 | SCRN3 | 79634 | 10 | 0 | 20 | |
| GSE43470 | SCRN3 | 79634 | 6 | 1 | 36 | |
| GSE46452 | SCRN3 | 79634 | 1 | 4 | 54 | |
| GSE47630 | SCRN3 | 79634 | 5 | 3 | 32 | |
| GSE54993 | SCRN3 | 79634 | 0 | 5 | 65 | |
| GSE54994 | SCRN3 | 79634 | 11 | 4 | 38 | |
| GSE60625 | SCRN3 | 79634 | 0 | 3 | 8 | |
| GSE74703 | SCRN3 | 79634 | 5 | 1 | 30 | |
| GSE74704 | SCRN3 | 79634 | 6 | 0 | 14 | |
| TCGA | SCRN3 | 79634 | 29 | 5 | 62 |
Total number of gains: 83; Total number of losses: 26; Total Number of normals: 379.
Somatic mutations of SCRN3:
Generating mutation plots.
Highly correlated genes for SCRN3:
Showing top 20/216 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCRN3 | FAF2 | 0.854742 | 3 | 0 | 3 |
| SCRN3 | HSPA4 | 0.799525 | 3 | 0 | 3 |
| SCRN3 | MED4 | 0.74904 | 3 | 0 | 3 |
| SCRN3 | ANKHD1 | 0.723625 | 3 | 0 | 3 |
| SCRN3 | RBAK | 0.720234 | 3 | 0 | 3 |
| SCRN3 | RTN4IP1 | 0.715882 | 3 | 0 | 3 |
| SCRN3 | YTHDF3 | 0.713745 | 3 | 0 | 3 |
| SCRN3 | MAP3K1 | 0.711459 | 3 | 0 | 3 |
| SCRN3 | RB1CC1 | 0.702783 | 3 | 0 | 3 |
| SCRN3 | USP32 | 0.697791 | 4 | 0 | 4 |
| SCRN3 | TAOK3 | 0.697515 | 3 | 0 | 3 |
| SCRN3 | ASCC3 | 0.69607 | 4 | 0 | 3 |
| SCRN3 | C2orf68 | 0.694745 | 3 | 0 | 3 |
| SCRN3 | CGGBP1 | 0.694676 | 3 | 0 | 3 |
| SCRN3 | AP1G1 | 0.694363 | 4 | 0 | 3 |
| SCRN3 | ZNF394 | 0.691986 | 3 | 0 | 3 |
| SCRN3 | EXOC6B | 0.688965 | 4 | 0 | 4 |
| SCRN3 | SPG11 | 0.688717 | 4 | 0 | 3 |
| SCRN3 | TAB2 | 0.688296 | 3 | 0 | 3 |
| SCRN3 | UBLCP1 | 0.687197 | 4 | 0 | 3 |
For details and further investigation, click here
